Miriam B. Goodman
Key Documents
Contact Information
- Academic Offices
Personal Information Email Tel (650) 721-5976 Tel (650) 723-8580Alternate Contact Jzesern Tan Administrative Assistant Email Tel Work 723-4900
Professional Overview
Administrative Appointments
- Associate Chair, Molecular and Cellular Physiology (2010 - present)
Honors and Awards
- Excellence in Graduate Teaching, Stanford School of Medicine (2011)
- Klingenstein Fellow in Neuroscience, The Klingenstein Fund (2005-2008)
- McKnight Scholar Award, McKnight Endowment (2005-2008)
- Prize in Neurobiology, Eppendorf & Science (2004)
- Alfred P. Sloan Fellow, Alfred P. Sloan Foundation (2002-2004)
Professional Education
| Ph.D.: | The University of Chicago, Neurobiology (1995) |
| Sc.B.: | Brown University, Biochemistry (1986) |
Postdoctoral Advisees
Amy Eastwood, Michael Krieg, Samuel Lasse, Valeria Vasquez, Dong Wang
Graduate & Fellowship Program Affiliations
Internet Links
Scientific Focus
Current Research Interests
We study the molecular events that give rise to the sensation of touch and temperature using C. elegans nematodes as a model system. To do this, we use a combination of quantitative behavioral analysis, genetics, in vivo electrophysiology, and heterologous expression of ion channels. We also collaborate with Pruitt's group in Mechanical Engineering (http://microsystems.stanford.edu) to develop and fabricate novel devices for the study of sensory transduction.
Publications
- Electrophysiological Methods for Caenorhabditis elegans Neurobiology. Methods Cell Biol. 2012: 409-36
- Alternatively spliced domains interact to regulate BK potassium channel gating. Proc Natl Acad Sci U S A. 2011; (51): 20784-9
- Caenorhabditis elegans body mechanics are regulated by body wall muscle tone. Biophys J. 2011; (8): 1977-85
- DEG/ENaC but not TRP channels are the major mechanoelectrical transduction channels in a C. elegans nociceptor. Neuron. 2011; (5): 845-57
- Heat avoidance is regulated by transient receptor potential (TRP) channels and a neuropeptide signaling pathway in Caenorhabditis elegans. Genetics. 2011; (1): 91-103
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