Mary Polan
Academic Appointments
- Emeritus Faculty, Acad Council, Obstetrics & Gynecology
- Member, Bio-X
Key Documents
Contact Information
- Academic Offices
Personal Information Email
Professional Overview
Administrative Appointments
- Chair, Stanford University School of Medicine - Obstetrics & Gynecology (1999 - present)
Scientific Focus
Current Research Interests
Dr. Polan's research has centered around ovarian function during both the follicular and luteal phases. Studies of steroidogenesis, LH receptor synthesis, and the involvement of the plasminogen activator system in ovarian events have been performed. In addition, this laboratory has investigated the synthesis and secretion of interleukin-1 by human peripheral monocytes as well as by human granulosa-luteal cells isolated from IVF patients. More recently this laboratory has focused on the role of IL-1, IL-1ra, and IL-1 type 1 receptor, as well as collagenase and TIMPs, in the process of embryonic implantation. Studies with IL-1 receptor antagonist have documented its ability to prevent implantation in the mouse model.
Publications
- The role of counseling for obstetric fistula patients: lessons learned from Eritrea. Patient Educ Couns. 2010; (2): 262-5
- Transforming growth interacting factor expression in leiomyoma compared with myometrium. Fertil Steril. 2010; (3): 1078-83
- Is lysyl oxidase-like protein-1, alpha-1 antitrypsin, and neutrophil elastase site specific in pelvic organ prolapse? Int Urogynecol J Pelvic Floor Dysfunct. 2009; (12): 1423-9
- Relaxin increases elastase activity and protease inhibitors in smooth muscle cells from the myometrium compared with cells from leiomyomas. Fertil Steril. 2009; (4 Suppl): 1351-4
- Effect of relaxin on TGF-beta1 expression in cultured vaginal fibroblasts from women with stress urinary incontinence. Reprod Sci. 2008; (3): 312-20
- Is alpha2-macroglobulin important in female stress urinary incontinence? Hum Reprod. 2008; (2): 387-93
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