Key Documents
Martin S. Angst
Academic Appointments
- Associate Professor - Med Center Line, Anesthesia
Contact Information
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Clinical Offices
Anesthesia 300 Pasteur Dr S276A MC 5117 Stanford, CA 94305 Tel Work (650) 498-5109 Fax (650) 725-8052
- Academic Offices
Personal Information EmailAdministrative Contact Jenny Hu Administrative Associate Email Tel Work (650) 723-9896Not for medical emergencies or patient use
Professional Snapshot
Clinical Focus
- Anesthesia
- Anesthesia for Liver Transplantation
- Neuroanesthesia
Professional Education
| Board Certification: | Anesthesia, Swiss Board of Anesthesiologists (1993) |
| Fellowship: | SUMC - Graduate Medical Education, CA (1996) |
| Residency: | University of Bern - Switzerland, Switzerland (1994) |
| Residency: | Regionalspital Burgdorf, Switzerland (1990) |
| Board Certification: | Anesthesia, European Board of Anesthesiologists |
Industry Relationships
Stanford is committed to ethical and transparent interactions with our industry partners. It is our policy to disclose payments of $5,000 or more, equity valued at $5,000 or more in a publicly traded company, or any equity in a privately held company, to physicians and scientists employed by Stanford University from companies or other commercial entities with which they interact as part of their professional activities. View Full Information
| Consulting: | Cortex Pharmaceuticals Inc. , Gowling Lafleur Henderson LLP , Sidley Austin LLP , Trigemina INc. , Vertex Pharmaceuticals LLC |
| Royalty Payments: | Trigemina INc. |
| Equity: | Cytonics Inc. , Trigemina INc. |
Scientific Focus
Current Research Interests
The human pain research laboratory was launched in 1995 as a translational research unit assisting the transfer of knowledge between basic and clinical sciences. Engaged in a bidirectional approach the lab is well positioned to examine how findings in the basic sciences apply to human biology, and to explore the validity and mechanistic implications of intriguing clinical observations under well controlled, “bench-like” conditions.
Our laboratory is active in three major and inter-related areas: the identification of pain biomarkers and potential analgesic targets, the early validation or rejection of novel analgesic interventions, and the pharmacogenomics and proteomics of opioid-analgesics. Pertinent questions are addressed with aid of experimental and clinical pain models (e.g. calibrated sunburns or surgical wounds), pharmacological tools (e.g. computer-controlled infusion algorithms), proteomic and genomic approaches (e.g. micro-catheter based techniques for tissue-specific sampling and analysis of cytokine and chemokine profiles), and imaging techniques (e.g. laser doppler imaging). The overarching goal of our research is to move towards a mechanism-based and individualized diagnosis and therapy of pain.
Clinical Trials
- Heritability of Opioid Effects: A Twin Study Recruiting
- A human in-vivo model for the detection of inflammatory and nociceptive biomarkers Completed
- Analgesic and Anti-inflammatory Effects of Electromagnetic Therapy (TMR) in Humans Completed
- Effects of a peripheral nerve block on biomarkers of pain and inflammation Completed
Publications
- Opioid Pharmacotherapy for Chronic Non-cancer Pain. J Pain. In Press
- Selective antagonism of opioid-induced ventilatory depression by an ampakine molecule in humans without loss of opioid analgesia. Clin Pharmacol Ther. 2010; (2): 204-11
- No evidence for the development of acute tolerance to analgesic, respiratory depressant and sedative opioid effects in humans. Pain. 2009; (1-2): 17-26
- Determining heat and mechanical pain threshold in inflamed skin of human subjects. J Vis Exp. 2009; (23)
- Epidural interferon gamma-immunoreactivity: a biomarker for lumbar nerve root irritation. Spine (Phila Pa 1976). 2009; (21): 2311-7
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