Luis de Lecea
Academic Appointments
- Professor, Psychiatry & Behavioral Science - Sleep Center
- Member, Bio-X
Key Documents
Contact Information
- Academic Offices
Personal Information EmailAlternate Contact Kerry Breuer Email
Professional Overview
Honors and Awards
- Integrative Behavioral Neuroscience Prize, ACNP (2010)
- Member. Board of Scientific Counselors, NIDA (2006-)
- Member, Faculty of 1000 (2008-)
Professional Education
| Postdoc: | The Scripps Research Institute, Molecular Neurobiology (1996) |
| Ph.D.: | University of Barcelona, Molecular Biology (1991) |
| B.Sc.: | University of Barcelona, Biology (1987) |
Postdoctoral Advisees
Patricia Bonnavion, Ada Eban-Rothschild, Simal Ozen Irmak, Clara Tourino Raposo
Graduate & Fellowship Program Affiliations
Internet Links
Scientific Focus
Current Research Interests
My lab uses molecular, optogenetic, anatomical and behavioral methods to identify and manipulate the neuronal circuits underlying brain arousal, with particular attention to sleep and wakefulness transitions. We are also interested in the changes that occur in neuronal circuits in conditions of hyperarousal such as stress and drug addiction.
Publications
- Optogenetic disruption of sleep continuity impairs memory consolidation. Proc Natl Acad Sci U S A. 2011; (32): 13305-10
- Optogenetic interrogation of dopaminergic modulation of the multiple phases of reward-seeking behavior. J Neurosci. 2011; (30): 10829-35
- Tuning arousal with optogenetic modulation of locus coeruleus neurons. Nat Neurosci. 2010; (12): 1526-33
- Phasic firing in dopaminergic neurons is sufficient for behavioral conditioning. Science. 2009; (5930): 1080-4
- Neural substrates of awakening probed with optogenetic control of hypocretin neurons. Nature. 2007; (7168): 420-4
- Transgenic mice with a reduced core body temperature have an increased life span. Science. 2006; (5800): 825-8
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