Lawrence Chu, MD, MS
Academic Appointments
- Assistant Professor - Med Center Line, Anesthesia
Contact Information
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Clinical Offices
Department of Anesthesia 300 Pasteur Dr H3580 MC 5640 Stanford, CA 94305 Tel Work (650) 724-2970 Fax (650) 725-8544Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
- Academic Offices
Administrative Contact Erin Reiland Administrative Assistant Email Tel Work 650-723-5439Not for medical emergencies or patient use
Professional Snapshot
Clinical Focus
- Anesthesia
Administrative Appointments
- Member, Committee on Admissions, Stanford University School of Medicine (2007 - present)
- Member, Web Site Committee, American Pain Society (2007 - present)
- Member, Educational Resources Committee, Society for Education in Anesthesia (2003 - present)
- Member, Editorial Board, MDNetGuide (1999 - present)
- Trustee, California Medical Association (2003 - 2004) View All 6administrative appointments of Lawrence Chu
Honors and Awards
- Career Development Award, National Institutes of Health (8/2004-8/2009)
- Clinical Loan Repayment Program, National Institutes of Health (7/2003 - Present)
- Research Fellowship Grant, Foundation for Anesthesia Education and Research (1/2003-6/2004)
- Excellence in Teaching Award, Stanford University Department of Biological Sciences (1998)
Professional Education
| Board Certification: | Anesthesia, American Board of Anesthesiology (2004) |
| Fellowship: | SUMC - Graduate Medical Education, CA (2004) |
| Residency: | SUMC - Graduate Medical Education, CA (2003) |
| Internship: | St. Mary's Hospital and Medical Center, CA USA (2000) |
| Medical Education: | Stanford University School of Medicine, CA (1999) |
Graduate & Fellowship Program Affiliations
Web Site Links
Scientific Focus
Current Research Interests
My research focuses on the study opiate-induced hyperalgesia in patients suffering from chronic pain.
I am currently conducting an NIH-funded five year double-blinded randomized controlled clinical study (NIGMS award 1K23GM071400-01) that prospectively examines the following hypotheses: 1) pain patients on chronic opioid therapy develop dose-dependent tolerance and/or hyperalgesia to these medications over time, 2) opiate-induced tolerance and hyperalgesia develop differently with respect to various types of pain, 3) opioid-induced hyperalgesia occurs independently of withdrawal phenomena, and 4) opiate-induced tolerance and hyperalgesia develop differently based on gender and/or ethnicity.
The study is the first quantitative and prospective examination of tolerance and hyperalgesia in pain patients and may have important implications for the rational use of opioids in the treatment of chronic pain.
Clinical Trials
- Effect of Beta Blockade on Opioid-Induced Hyperalgesia in Humans Recruiting
- Inflammatory Responses to Acute and Chronic Opioid Exposure in Humans Recruiting
- POWS: Palonosetron/Ondansetron Opioid Withdrawal Study Recruiting
- fMRI Imaging of Opioid Withdrawal in Healthy Human Volunteers Enrolling by Invitation
Publications
- Anesthesia 2.0: Internet-based information resources and Web 2.0 applications in anesthesia education. Curr Opin Anaesthesiol. 2010
- Molecular Basis and Clinical Implications of Opioid Tolerance and Opioid-induced Hyperalgesia Acute Pain Management, Cambridge University Press, New York, New York. 2009
- Ondansetron: an effective treatment for the withdrawal symptoms of opioids? Therapy. 2009; (5): 637-640
- Bilateral infraorbital nerve blocks decrease postoperative pain but do not reduce time to discharge following outpatient nasal surgery. Can J Anaesth. 2009; (8): 584-9
- Anesthesia-controlled time and turnover time for ambulatory upper extremity surgery performed with regional versus general anesthesia. J Clin Anesth. 2009; (4): 253-7
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