Jan van Riggelen
Academic Appointments
- Postdoctoral Research fellow, School of Medicine
Professional Snapshot
Honors and Awards
- Postdoc Fellowship, Lymphoma Research Foundation (2006-2008)
Professional Education
| Diploma: | University of Heidelberg, Molecular Biology (2000) |
| Doctor of Philosophy: | Ruprecht Karl Universitat Heidelberg, (2005) |
Faculty Advisor
Graduate & Fellowship Program Affiliations
Web Site Links
Scientific Focus
Research Interests
The Impact of Epigenetics on MYC-induced Tumorigenesis
Publications
- Cellular senescence is an important mechanism of tumor regression upon c-Myc inactivation. Proc Natl Acad Sci U S A. 2007; (32): 13028-33
- Sustained regression of tumors upon MYC inactivation requires p53 or thrombospondin-1 to reverse the angiogenic switch. Proc Natl Acad Sci U S A. 2006; (44): 16266-71
- Loss of net as repressor leads to constitutive increased c-fos transcription in cervical cancer cells. J Biol Chem. 2005; (5): 3286-94
- Ectopic expression of nonliganded retinoic acid receptor beta abrogates AP-1 activity by selective degradation of c-Jun in cervical carcinoma cells. J Biol Chem. 2004; (44): 45408-16
- Disturbance of tumor necrosis factor alpha-mediated beta interferon signaling in cervical carcinoma cells. J Virol. 2002; (1): 280-91
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