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James FerrellAcademic Appointments
Appointment
Organization
Professor
Professor
Member
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Administrative Appointments
Title
Organization
Start Year
End Year
Chair
Stanford University School of Medicine - Chemical & Systems Biology
2006
-
Professional Education
Degree
Awarding Institution
Field of Study
Year of Graduation
B.A.
Williams College
Physics, Chemistry, Mathematics
1976
Ph.D.
Stanford University
Chemistry
1984
M.D.
Stanford University
1986
Postdoctoral Advisees
Sun Kim,
Silvia Magalhaes Dos Santos
Web Site Links
Research/Lab website:
http://www.stanford.edu/group/ferrelllab/
Research Interests
Our research centers on the signal transduction circuits that trigger the entry into mitotic and meoitic M-phase, the progression through these phases, and the exit from M-phase to interphase.
Some of our work is aimed at identifying as-yet unidentified components of these regulatory circuits. The rest of our work is aimed at understanding the systems level logic of these circuits--how cells build reliable switches, oscillators, and response networks out of imperfect components.
Some of our work is aimed at identifying as-yet unidentified components of these regulatory circuits. The rest of our work is aimed at understanding the systems level logic of these circuits--how cells build reliable switches, oscillators, and response networks out of imperfect components.
Community and International Work
- PRD-1-Day Band Performance, Opening Ceremony, Guangzhou Triennial, Guangzhou, China More »
Publications
- Ferrell JE, "Feedback regulation of opposing enzymes generates robust, all-or-none bistable responses." Curr Biol 2008; 18: 6: R244-5 More »
- Hendrickson DG, Hogan DJ, Herschlag D, Ferrell JE, Brown PO "Systematic Identification of mRNAs Recruited to Argonaute 2 by Specific microRNAs and Corresponding Changes in Transcript Abundance." PLoS ONE 2008; 3: 5: e2126 More »
- Tsai TY, Choi YS, Ma W, Pomerening JR, Tang C, Ferrell JE "Robust, Tunable Biological Oscillations from Interlinked Positive and Negative Feedback Loops." Science 2008; 321: 5885: 126-129 More »
- Pomerening JR, Ubersax JA, Ferrell JE "Rapid Cycling and Precocious Termination of G1 Phase in Cells Expressing CDK1AF." Mol Biol Cell 2008; More »
- Gong D, Pomerening JR, Myers JW, Gustavsson C, Jones JT, Hahn AT, Meyer T, Ferrell JE "Cyclin A2 regulates nuclear-envelope breakdown and the nuclear accumulation of cyclin b1." Curr Biol 2007; 17: 1: 85-91 More »
82 publications: view full list
