Holden Maecker
Academic Appointments
- Associate Professor (Research), Microbiology & Immunology
- Member, Bio-X
Key Documents
Contact Information
- Academic Offices
Personal Information Email Tel (650) 723-1671
Professional Overview
Administrative Appointments
- Director, Human Immune Monitoring Center (2009 - present)
Professional Education
| PhD: | Stanford University, Cancer Biology (1988) |
| BS: | Purdue University, Microbiology (1984) |
Graduate & Fellowship Program Affiliations
Community and International Work
- Human Immunophenotyping Consortium, International
Internet Links
Scientific Focus
Current Research Interests
My research focuses on cellular immune responses to pathogens, and the correlation of those responses with protection from clinical disease. Most of my work and collaborations involve systems-level assays for immune monitoring of diseases like cytomegalovirus (CMV), HIV, and cancer. I'm interested in determining immune correlates of protection for such diseases, where cellular immunity is important. This in turn would enable better vaccine development and monitoring of individuals undergoing immunotherapy.
Publications
- Apoptosis and other immune biomarkers predict influenza vaccine responsiveness. Mol Syst Biol. 2013: 659
- Experimental pain and opioid analgesia in volunteers at high risk for obstructive sleep apnea. PLoS One. 2013; (1): e54807
- Mass cytometry: protocol for daily tuning and running cell samples on a CyTOF mass cytometer. J Vis Exp. 2012; (69): e4398
- NK cells are dysfunctional in human chronic myelogenous leukemia before and on imatinib treatment and in BCR-ABL-positive mice. Leukemia. 2012; (3): 465-74
- New tools for classification and monitoring of autoimmune diseases. Nat Rev Rheumatol. 2012; (6): 317-28
- Reducing variability in flow cytometry. Nat Rev Immunol. 2012; (5): 396
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