Heike Daldrup-Link
Academic Appointments
- Associate Professor, Radiology - Pediatric Radiology
- Member, Child Health Research Institute
- Member, Bio-X
- Member, Stanford Cancer Institute
Key Documents
Contact Information
-
Clinical Offices
Pediatric Radiology 725 Welch Road, Ste 1679 MC 5913 Palo Alto, CA 94304 Tel Work (650) 725-2548 Fax (650) 497-8745Practices at Stanford Hospital and Clinics and Lucile Packard Children's Hospital
- Academic Offices
Alternate Contact Danielle Beecham Administrative Assistant Email Tel Work (650) 723-8406Not for medical emergencies or patient use
Professional Overview
Clinical Focus
- Radiology
- Pediatric Radiology
- Pediatric Oncology Imaging
Administrative Appointments
- Co-Chair (with S. Voss, MGH), ACR Committee on Pediatric Imaging Research, American College of Radiology (2013 - present)
- Category Chair for “Stem Cell and Immune Cell Tracking", WMIC, World Molecular Imaging Congress (2012 - present)
- Member, SPR Bylaws Committee, Society for Pediatric Radiology (2012 - present)
- Associate Editor/Contrast Media, Radiology (2011 - present)
- Elected Member, Board of Directors of the SPR, Society for Pediatric Radiology (2010 - present)
- NIH Study Section Member, Cancer Immunopathology and Immunotherapy Study Section (CII) (2010 - 2016)
Honors and Awards
- R.O.S.E. Award (Recognition of Service Excellence), Lucile Packard Children's Hospital, Stanford University (2012)
- Distinguished Investigator Award, Academy of Radiology Research (2012)
- Berdon Award for the best basic science paper, published in Pediatric Radiology in 2011, Society for Pediatric Radiology (2012)
- Research featured on the cover of the September issue, Clinical Cancer Research (2011)
- Author of the 10th and 17th most cited articles (out of 1,100 articles), Journal of Visualized Experiments (2011)
- Distinguished Reviewer, Journal of Magnetic Resonance Imaging, International Society for Magnetic Resonance in Medicine (2011)
Professional Education
| Residency: | University of Munster, Medical School, Germany (03/31/2000) |
| Internship: | University of Munster, Medical School, Germany (12/31/1995) |
| Fellowship: | Schwabing Children's Hospital (Kinderklinkik Schwabing), Germany (05/30/2003) |
| Residency: | Technical University of Munich, Germany (05/31/2001) |
| Fellowship: | UCSF Department/Division of Radiology CA (02/28/1997) |
| Medical Education: | University of Munster, Medical School, Germany (11/25/1993) |
Postdoctoral Advisees
Celina Ansari, Christopher Klenk, Hossein Nejadnik, Tarsheen Sethi, Qiaoyun Shi
Graduate & Fellowship Program Affiliations
Community and International Work
Internet Links
Scientific Focus
Current Research Interests
Cells are the basic units of life. They determine normal organ function and disease development. Observations of living cells are vital to understanding, diagnosing, and successfully treating disease. Our research group develops cell specific contrast agents and non-invasive imaging techniques that can generate detailed information about specific cells in the body. Our research program focuses on two main applications
1. Cancer Imaging
2. Stem Cell Imaging
mostly utilizing MR imaging technology. We investigate the value of clinically applicable macrophage-targeted nanoparticles for improved tumor detection and for the diagnosis of tumor-associated inflammation. In addition, we explore the value of novel cell-targeted contrast agents and "smart", activatable contrast agents for diagnosing successful or unsuccessful stem cell therapies. And we develop immune cell tracking techniques for non-invasive diagnosis of stem cell transplant rejection. Currently, the diagnosis of diseases and their treatment almost always involves acquiring and repeating multiple imaging tests, which are time-consuming, cause direct and indirect accumulated expenses and accumulated radiation exposures. We ultimately aim to combine tailored cell specific contrast agents with whole body imaging techniques in order to create one single diagnostic test, which provides comprehensive "one-stop" evaluations of tumor and stem cell therapies.
Weblink: http://mips.stanford.edu/research/daldrup-link-lab.html
Publications
- Evaluation of the novel USPIO GEH121333 for MR imaging of cancer immune responses. Contrast Media Mol Imaging. 2013 May-Jun; (3): 281-8
- Ferumoxytol: a new, clinically applicable label for stem-cell tracking in arthritic joints with MRI. Nanomedicine (Lond). 2013
- Differentiation of normal thymus from anterior mediastinal lymphoma and lymphoma recurrence at pediatric PET/CT. Radiology. 2012; (2): 613-22
- Intravenous ferumoxytol allows noninvasive MR imaging monitoring of macrophage migration into stem cell transplants. Radiology. 2012; (3): 803-11
- Somatic differentiation and MR imaging of magnetically labeled human embryonic stem cells. Cell Transplant. 2012; (12): 2555-67
- MRI of tumor-associated macrophages with clinically applicable iron oxide nanoparticles. Clin Cancer Res. 2011; (17): 5695-704
Help