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Firdaus DhabharAcademic Appointments
Appointment
Organization
Associate Professor
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Honors & Awards
Title
Organization
Date(s)
Young Investigator Award
PsychoNeuroImmunology Research Society
2000
Distinguished Dissertation Award - Life Sciences
Council of Graduate Schools
1997
Administrative Appointments
Title
Organization
Start Year
End Year
Director of Research
Stanford Center on Stress & Health
2006
-
Professional Education
Degree
Awarding Institution
Field of Study
Year of Graduation
Ph.D.
The Rockefeller University
Biomedical Sciences -- Neuroimmunology
1996
AB
Dartmouth College
Biological Science
1990
AB
Dartmouth College
Government
1990
Research Interests
Although stress has a bad reputation, a physiological stress is response is nature's fundamental survival system. I am interested in identifying biological mechanisms that mediate and differentiate the recently appreciated immunoenhancing effects of short-term stress from the long-known immunosuppressive effects of chronic stress. We examine stress effects on leukocyte trafficking, innate/adaptive immunity, and cytokine gene/protein expression using models of skin immunity, surgery, and cancer.
By elucidating the mechanisms under investigation we hope to develop behavioral and/or pharmacologic interventions designed to harness a patient’s psycho-physiology to selectively enhance (during vaccination, surgery, infection, or cancer) or suppress (during inflammatory and autoimmune disease) an immune response depending on the clinical needs of the patient.
By elucidating the mechanisms under investigation we hope to develop behavioral and/or pharmacologic interventions designed to harness a patient’s psycho-physiology to selectively enhance (during vaccination, surgery, infection, or cancer) or suppress (during inflammatory and autoimmune disease) an immune response depending on the clinical needs of the patient.
Community and International Work
- Institute of Medicine Committee: Interactions Among Social, Behavioral and Genetic Factors In Health More »
- Institute for Laboratory Animal Research Committee: Humane Transport of Laboratory Animals More »
- Scientific Council Member, Psychoneuroimmunology Research Society More »
- Institute of Medicine Committee: Health Effects of Exposures Experienced During The Gulf War (I). More »
Publications
- Antoni MH, Lutgendorf SK, Cole SW, Dhabhar FS, Sephton SE, McDonald PG, Stefanek M, Sood AK "The influence of bio-behavioural factors on tumour biology: pathways and mechanisms." Nat Rev Cancer 2006; 6: 3: 240-8 More »
- Saul AN, Oberyszyn TM, Daugherty C, Kusewitt D, Jones S, Jewell S, Malarkey WB, Lehman A, Lemeshow S, Dhabhar FS "Chronic stress and susceptibility to skin cancer." J Natl Cancer Inst 2005; 97: 23: 1760-7 More »
- Dhabhar FS, Viswanathan K "Short-term stress experienced at time of immunization induces a long-lasting increase in immunologic memory." Am J Physiol Regul Integr Comp Physiol 2005; 289: 3: R738-44 More »
- Viswanathan K, Daugherty C, Dhabhar FS "Stress as an endogenous adjuvant: augmentation of the immunization phase of cell-mediated immunity." Int Immunol 2005; 17: 8: 1059-69 More »
- Viswanathan K, Dhabhar FS "Stress-induced enhancement of leukocyte trafficking into sites of surgery or immune activation." Proc Natl Acad Sci U S A 2005; 102: 16: 5808-13 More »
47 publications: view full list
