 |
 |
 |
Eric I. Knudsen
Academic Appointments
Appointment
Organization
Professor
Graduate & Fellowship Program Affiliations
|
|
|
Honors & Awards
Title
Organization
Date(s)
Peter Gruber Prize in Neuroscience
Society for Neuroscience
2005
Member
National Academy of Sciences
2002
Edward C. and Amy H. Sewall Professorship
Stanford University School of Medicine
1995
Troland Research Award
National Academy of Sciences
1988
Young Investigator Award
Society for Neuroscience
1984
Administrative Appointments
Title
Organization
Start Year
End Year
Chair
Stanford University School of Medicine - Neurobiology
2001
2005
Professor
Stanford University School of Medicine - Neurobiology
1988
-
Professional Education
Degree
Awarding Institution
Field of Study
Year of Graduation
B.A.
UC, Santa Barbara
Zoology
1971
M.A.
UC, Santa Barbara
Neuroscience
1973
Ph.D.
UC, San Diego
Neuroscience
1976
Research Interests
We study mechanisms of attention, learning and strategies of information processing in the central auditory system of developing and adult barn owls, using neurophysiological, pharmacological, anatomical and behavioral techniques. Studies focus on the process of sound localization. Sound localization is shaped powerfully by an animal's auditory and visual experience. Experiments are being conducted to elucidate developmental influences, extent and time course of this learning process, and its dependence on visual feedback. The cellular mechanisms that underlie this example of learning are being studied to determine how experience adaptively alters the anatomical, pharmacological and functional properties of the brain in developing and adult animals. In addition, we study mechanisms of attention (gain control of sensory responses) and the rules by which auditory and visual information is combined into a single representation in the brain. Techniques offered in this laboratory include acoustic stimulation, extracellular recording, microstimulation, neuropharmacology, immunohistochemistry, anatomical pathway tracing, and behavioral analysis.
Community and International Work
-
National Scientific Council on the Developing Child, Washington D.C. More »
Publications
-
Knudsen EI,
"Fundamental Components of Attention."
Annu Rev Neurosci
2007;
More »
-
Keuroghlian AS,
Knudsen EI
"Adaptive auditory plasticity in developing and adult animals."
Prog Neurobiol
2007;
82:
3:
109-21
More »
-
Goddard CA,
Knudsen EI, Huguenard JR
"Intrinsic Excitability of Cholinergic Neurons in the Rat Parabigeminal Nucleus."
J Neurophysiol
2007;
More »
-
Winkowski DE,
Knudsen EI
"Top-down control of multimodal sensitivity in the barn owl optic tectum."
J Neurosci
2007;
27:
48:
13279-91
More »
-
Winkowski DE,
Knudsen EI
"Top-down gain control of the auditory space map by gaze control circuitry in the barn owl."
Nature
2006;
439:
7074:
336-9
More »