Key Documents
Dritan Agalliu PhD
Academic Appointments
- Postdoctoral Research fellow, Neurobiology
Contact Information
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Academic Offices
Personal Information Email Tel (650) 498-7901
Professional Snapshot
Professional Education
| Doctor of Philosophy: | Columbia University, (2006) |
| B.S.: | University of Minnesota, Genetics and Cell Biology (1998) |
Faculty Advisor
Scientific Focus
Research Interests
I am interested in understanding the signaling pathways that regulate the development of specialized tight junctions in brain endothelial cells responsible for forming the blood-brain barrier. The identification of these signals is important for elucidating the mechanisms that regulate the entry of distinct compounds or drugs into the Central Nervous System (CNS) and the etiology of pathological CNS conditions associated with blood-brain barrier breakdown.
Publications
- Myelin gene regulatory factor is a critical transcriptional regulator required for CNS myelination. Cell. 2009; (1): 172-85
- Heterogeneity in the developmental potential of motor neuron progenitors revealed by clonal analysis of single cells in vitro. Neural Dev. 2009: 2
- Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis. Proc Natl Acad Sci U S A. 2009; (2): 641-6
- Motor neurons with axial muscle projections specified by Wnt4/5 signaling. Neuron. 2009; (5): 708-20
- Wnt5a signaling induces proliferation and survival of endothelial cells in vitro and expression of MMP-1 and Tie-2. Mol Biol Cell. 2006; (12): 5163-72
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