Bill Burkholder
Academic Appointments
Appointment
Organization
Assistant Professor
Member
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Web Site Links
Research/Lab website:
Burkholder lab web site
Research Interests
Our lab is interested in how bacteria monitor and coordinate cell cycle events. We are focused on identifying and characterizing signal transduction pathways used by the bacterium Bacillus subtilis to regulate cell cycle progression and development in response to chromosome status. Our goal is to understand how these pathways work mechanistically and how they contribute to normal growth, development, and genome stability.
Publications
- Rowland SL, Burkholder WF, Cunningham KA, Maciejewski MW, Grossman AD, King GF "Structure and mechanism of action of Sda, an inhibitor of the histidine kinases that regulate initiation of sporulation in Bacillus subtilis." Mol Cell 2004; 13: 5: 689-701 More »
- Burkholder WF, Kurtser I, Grossman AD "Replication initiation proteins regulate a developmental checkpoint in Bacillus subtilis." Cell 2001; 104: 2: 269-79 More »