2:30 PM - 3:30 PM
Seminar Series: John Groopman
The Changing Etiology and Rise of Liver Cancer: Opportunities for Prevention in High-Risk Communities
Collectively liver cancer, including hepatocellular carcinoma (HCC) and cholangiocarcinoma, accounts for 9.1% of all reported cancer deaths and is the second most common cause of cancer mortality worldwide. The incidence of liver cancer varies enormously globally and unfortunately the burden of this nearly always fatal disease is much greater in the less economically developed countries of Asia and sub-Saharan Africa . HCC is also the most rapidly rising solid tumor in the US and Central America and is overrepresented in minority communities, including African-Americans, Hispanic/Latino-Americans and Asian-Americans .
Overall, there are more than 750,000 new cases each year and more than 300,000 deaths annually in the People’s Republic of China (P.R.C.) alone . In contrast with most common cancers in the economically developed world where over 90% of cases are diagnosed after the age of 45, in high-risk regions for liver cancer onset begins to occur in both men and women by 20 years of age and peaks between 40-49 years of age in men and between 50-59 years of age in women.