PHIND Seminar Series - Michael L. Eisenberg, MD

Infertility impacts approximately 1 in 7 couples in the U.S. Nearly 50% of infertile couples will have a male factor to explain reproductive difficulties. Importantly, male fertility may provide a window into future health with data suggesting that men with infertility have higher rates of cancer, metabolic disease, and mortality. Select comorbid conditions (e.g. obesity, smoking) are known to impact male fertility and health; however, the etiology of the association remains unknown. Data suggests genetic, in utero, and hormonal factors may contribute. The findings suggest an opportunity to positively affect men’s health. If infertility is confirmed as an early marker of chronic disease, screening practices could be adjusted, as they are for patients with a family history of malignancy.