Peltz Lab In the Department of Anesthesia

Peltz Lab Publications

sciencegenome_rescomputationalanesthesiology

93 papers as of 2/12/12

2011-12

M. Zheng, G. Peltz.  Genetic discovery: The prescription for chronic pain. Genomic Medicine 2:82-84, 2011.

Hasegawa M, Kawai K, Mitsui T, Taniguchi K, Monnai M, Wakui M, Ito M, Suematsu M, Peltz G, Nakamura M et al: The reconstituted 'humanized Liver' in TK-NOG mice is mature and functional. Biochem Biophys Res Commun2011, 405(3):405-410.

G. Peltz. Immunomodulation in perioperative medicine. Pain Management In press, 2011.

A.C.M. Boon, D. Finkelstein, G. Liao, M. Zheng, J. Allard, K. Klump, R. Webster, G. Peltz, R.J. Webby. Outcome of H5N1 influenza infection in genetically diverse mice is mediated at the level of viral load (2011) mBio 2(5). pii: e00171-11. PMID: 21896679

Peltz G, Zaas AK, Zheng M, Solis NV, Zhang MX, Liu H-H, Hu Y, Boxx GM, Phan QT, Dill D, and S. Filler. Next-Generation Computational Genetic Analysis: Multiple Complement Alleles Control Survival After Candida Albicans Infection and Immunity (2011): 79: 4472-79. PMID: 21875959

M. Zheng, M, Dill D., Peltz, G. A Better Prognosis for Genetic Association Studies in Mice Trends in Genetics (2012) 28 (2):62-69.

Sorge, R. E., T. Trang, R. Dorfman, S. B. Smith, S. Beggs, J. Ritchie, J.-S. Austin, D. V. Zaykin, H. V. Meulen, M. Costigan, T. A. Herbert, M. Yarkoni-Abitbul, D. Tichauer, J. Livneh, E. Gershon, M. Zheng, K. Tan, S. L. John, G. D. Slade, J. Jordan, C. J. Woolf, G. Peltz, W. Maixner, L. Diatchenko, Z. Seltzer, M. W. Salter, and J. S. Mogil.  Nature Medicine In Press 2012.

H-H. Liu, Y. Hu, M. Zheng, M.M. Suhoski, E.G. Engleman, D. Dill, M. Hudnall, J. Wang, R. Spolski, W.J. Leonard and G. Peltz. Cd14 SNPs Regulate the Innate Immune Response. Molecular Immunology, In Press, 2012.

2010

H.-H. Liu, P. Lu, Y. Guo, E. Farrell, X. Zhang, M. Zheng, B. Bosano, Z. Zhang, J. Allard, G. Liao, S. Fu, J. Chen, K. Dolim, A. Kuroda, J. Usuka, J. Cheng, W. Tao, K. Welch., Y. Liu, J. Pease, S.A. de Keczer, M. Masjedizadeh, J.-S. Hu, P. Weller, T. Garrow, and G. Peltz. Bhmt2 is a Genetic Susceptibility Factor For Acetaminophen-Induced Liver Toxicity. Genome Research, 20:28-35, 2010.

L. Gong, D. Hirschfeld, Y-C. Tan, J. H. Hogg, G. Peltz, Z. Avnur, P. Dunten. Discovery of potent and bioavailable GSK-3b inhibitors (2010). Bioorganic & Medicinal Chemistry Letters, 20:1693–1696.

X. Zhang, H-H. Liu, P. Weller, M. Zheng, J. Wang, G. Liao, M. Monshouwer and G. Peltz. In Silico and In Vitro Pharmacogenetics: Aldehyde Oxidase Rapidly Metabolizes a P38 Kinase Inhibitor.  The Pharmacogenomics Journal, In Press, 2010.

X. Li, P. Sahbaie, M. Zheng, J. Ritchie, G. Peltz, J.S. Mogil and J. D. Clark. Expression Genetics Identifies Spinal Mechanisms Supporting Formalin Late Phase Behaviors. 
Molecular Pain, 6:11, 2010.

M. Zheng, P. Ravindran, J. Wang, D. Chen, A. Butte and G. Peltz. An Optimistic Prognosis for the Clinical Utility of Laboratory Data. Anesthesia & Analgesia In press, 2010.

Y. Hu, D. Liang, X. Li, H-H. Liu, Xun Zhang, M. Zheng, D. Dill, X. Shi, Y. Qiao, D. Yeomans, B. Carvalho, M.S. Angst, J.D. Clark, G. Peltz. The Role of IL-1 in Wound Biology Part I: Murine in Silico and In vitro Experimental Analysis. Anesthesia & Analgesia In press, 2010.

Y. Hu, D. Liang, X. Li, H-H. Liu, Xun Zhang, M. Zheng, D. Dill, X. Shi, Y. Qiao, D. Yeomans, B. Carvalho, M.S. Angst, J.D. Clark, G. Peltz. The Role of IL-1 in Wound Biology Part II: In vivo and Human Translational Studies. Anesthesia & Analgesia.
In press, 2010.

J.S. Tregoning, Y. Yamaguchi, B. Wang, D. Mihm, J.A. Harker, E.S.C. Bushell, M. Zheng, G. Liao, G. Peltz and P.J.M. Openshaw. Genetic Susceptibility to the Delayed Sequelae of RSV Infection is MHC-Dependent, but Modified by Other Genetic Loci. J. Immunol. In press, 2010.

2009

Chu, L., Liang, D,L., Li, X., Sahbaie, P., D’Arcy, N., Liao, G., Peltz, G. and J. D, Clark.  From Mouse to Man: The 5HT3 Receptor Modulates Physical Dependence on Narcotic Drugs.  Pharmacogenetics and Genomics, 19:193-205, 2009.

M.L. LaCroix-Fralish, S.B. Smith, G. Mo, S.G. Sotocinal, J. Ritchie, J.-S. Austin, K. Melmed, T.H. Lee, D. Romanovsky, G. Liao, M.A. Behlke, D. J. Clark, G. Peltz, P. Séguéla, M. Dobretsov and J.S. Mogil. Genetic Variation within the b3 Subunit (Atp1b3) of the Na+,K+-ATPase Alters Inflammatory Pain Sensitivity. Pain, 144:294-302, 2009.

M. Zheng, S. Shafer, G. Liao, H-H Liu, and G. Peltz. Computational Genetic Mapping in Mice: ‘The Ship has Sailed.’ Science Translational Medicine. 1, 3ps4, 2009.

2008

E.Y. Kim, J.T. Battaile, A.C. Patel, E. Agapov, M.H. Grayson, Y. You, Y. Alevy, J. Tucker, S. Swanson, J.W. Tyner, J.D. Morton, M.Castro, G.A. Patterson, J.C. Woods, G. Reto, A. Schwendener, J.D. Allard, G. Peltz, and M.J. Holtzman (2008). Persistent activation of an innate NKT cell-macrophage immune axis translates respiratory viral infection into chronic inflammatory lung disease. Nature Medicine, 14:633-40, 2008.

Aimee Zaas, Guochun Liao, Jason Chien, Jonathan Usuka, Clarice Weinberg, David Shore, Steven Giles, Kieren Marr, Lauranell Burch, Lalith Perara, John Perfect, Gary Peltz, David Schwartz. Plasminogen Alleles Influence Susceptibility to Invasive Aspergillosis (2008).  PLOS Genetics, 4: 1-8, 2008.

Sabsovitch, I., Clark, J.D., Liao, G., Peltz, G., Lindsey, D.P., Jacobs, J.R., Yao, W., Guo, T-Z., W.S. Kingery.  Bone Microstructure and its Associated Genetic Variability in 12 Inbred Mouse Strains: µCT Study and In Silico Genome Scan. Bone, 42:439-51, 2008.

S.B. Smith, C.L. Marker, C. Perry, S.G. Sotocinal, J.-S. Austin, K. Melmed, G. Liao, G. Peltz, D.J. Clark, K. Wickman, and J.S. Mogil. Quantitative Trait Locus and Computational Mapping Identifies Kcnj9 (GIRK3) as a Candidate Gene Affecting Analgesia from Multiple Drug Classes (2008), Pharmacogenetics and Genomics, 18:231-41, 2008.

G. Liao, X. Zhang, J.D. Clark, G. Peltz.  A Genomic ‘Roadmap’ to ‘Better’ Drugs (2008).  Drug Metabolism Reviews, 40:225-39, 2008.

Moffett, S. P., Oakley, J. I., Cauley, J. A., Lui, L. Y., Ensrud, K. E., Taylor, B. C., Hillier, T. A., Hochberg, M. C., Li, J., Cayabyab, S., Lee, J. M., Peltz, G., Cummings, S. R., Zmuda, J. M. Osteoprotegerin Lys3Asn Polymorphism and the Risk of Fracture in Older Women. Journal of Clinical Endocrinology and Metabolism.  93: 2002-8, 2008.

G.J. Tranah, B.C. Taylor, Li-Y. Liu, J.M. Zmuda, J.A. Cauley, Kristine E. Ensrud, T.A. Hillier, M.C. Hochberg, J. Li, Brian Rhees, H. Erlich, M.D. Sternlicht, G. Peltz, and S. R.
Cummings, for the SOF Research Group (2008).  A candidate gene study of fracture risk and bone mineral density: results from the Study of Osteoporotic Fractures. Calcified Tissue International.  83:155-166.

Hiroshi Suemizu, Masami Hasegawa, Kenji Kawai, Kenji Taniguchi, Makoto Monnai, Masatoshi Wakui, Makoto Suematsu, Mamoru Ito, Gary Peltz and Masato Nakamura (2008).  Establishment of a humanized model of liver using NOD/Shi-scid IL2Rgnull mice.  Biochemical Biophysical Research Communications, 377:248-252.

2007

Yingying Guo, Erin Farrell, Peng Lu, Paul Weller, Jianmei Wang, Guochun Liao, Zhaomei Zhang, Steven Hu, John Allard, Steve Shafer, Jonathan Usuka, and Gary Peltz.  In silico and In vitro Computational Pharmacogenetics in mice.  Proceedings of the National Academy of Science (USA), 104:17735-40, 2007.

J.G. Koch, X. Gu, Y. Han, A. El-Naggar, D. Medina, D. J. Jerry, A. C. Blackburn, G. Peltz, C. Amos, and G. Lozano.  Mammary tumor modifiers in BALB/cJ mice heterozygous for p53.  Mammalian Genome, 18:300-309, 2007.

A.C. Blackburn, Hill, L.Z., Roberts A., Wang, J., Aud, D., Jung, J., Nikolcheva, T., Allard, J., Otis, C.N., Cao, J., Ricketts S.J.R., Naber, S.P., Dickinson E., Peltz, G.,  and D.J. Jerry. Low DMBT1 Expression Correlates with Breast Cancer Susceptibility in Mice and Humans. Am. J. Pathology, 170:2030-2041, 2007.

Cascio,  M., Xing, Y., Gong, D., Popovich, J., Eger, E., Saunak Sen, Peltz, G., Sonner, J.M.  Mouse chromosome 7 harbors a quantitative trait locus for isoflurane minimum alveolar concentration.  Anesthesia and Analgesia, 105: 381-385, 2007.

Moffett, S.P., Zmuda, J.M., Cauley J.A., Ensrud K.E., Hillier T.A., Hochberg M.C., Li J., Cayabyab S., Lee J. M, Peltz G., Cummings S.R. Association of the VDR translation start site polymorphism and fracture risk in older women. Journal of Bone and Mineral Research, 22: 730-6, 2007.

Adachi, K., Mirzadeh, Z., Sakaguchi, M., Yamashita. T., Nikolcheva, T., Peltz, G., Gong, L., Gotoh, Y., Alvarez-Buylla, A., Kawase,  T., Okano, H., and Sawamoto, K.  b-catenin Signaling Promotes Proliferation of Progenitor Cells in the Adult Mouse Subventricular Zone.  Stem Cells, 25: 2827-36, 2007.

Zheng, M., Lu, P., Liu, Y., Pease, J., Usuka, J., Peltz, G., and Guochun Liao.  An Automated Method for Analysis of 2-Dimensional 1H-13C NMR Spectra (2007). Bioinformatics, 21:2926-2933.

Sabsovitch, I., Clark, J.D., Liao, G., Peltz, G., Lindsey, D.P., Jacobs, J.R., Yao, W., Guo, T-Z., W.S. Kingery.  Bone Microstructure and its Associated Genetic Variability in 12 Inbred Mouse Strains: µCT Study and In Silico Genome Scan. Bone, 42:439-51, 2008.

2006

Guo, Y., Weller, P., Farrell, E., Cheung, P.,  Fitch, B., Clark, D., Wu,S.-Y., Wang, J., Liao, G., Zhang, Z., Allard, J., Cheng, J., Nguyen, A., Jiang, S., Shafer, S., Usuka, J., Masjedizadeh, M. and G. Peltz.  In Silico Pharmacogenetics: Warfarin Metabolism. Nature Biotechnology, 24: 531-536, 2006.

D-Y. Liang, G. Liao, G. Lighthall, G. Peltz and J. D. Clark (2006). Genetic Variants of the P-Glycoprotein Gene Abcb1b Modulate Opioid-Induced Hyperalgesia, Tolerance and Dependence. Pharmacogenetics and Genomics, 16: 825-835, 2006.

Liang, D., Liao, G., Wang, J., Usuka, J., Gou, J., Peltz, G. and Clark, D.J.  Genetic Analysis of Opioid-Induced Hyperalgesia in Mice. Anesthesiology, 104: 1054-1062, 2006.

A.C. Patel J.D. Morton, E.Y. Kim, Y. Alevy, S. Swanson, J. Tucker, G. Huang, E. Agapov, T.E. Phillips, J.D. Allard, K. Dabbagh, G. Peltz, and M.J. Holtzman.  Genetic segregation of airway disease traits despite redundancy of chloride channel calcium-activated (CLCA) family members.  Physiological Genomics.  25: 502-513, 2006.

D.Y. Liang, T. Guo, G. Liao, W. Kingery, G. Peltz and J.D. Clark.  Chronic Pain and Genetic Background Interact and Influence Opioid Analgesia, Tolerance and Physical Dependence.  Pain. 121: 232-240, 2006.

Y. Guo, P. Weller, J. Allard, J. Usuka, M. Masjedizadeh, S-Y. Wu, B. Fitch, D. Clark, J.D. Clark, S. Shafer, J. Wang, G. Liao and G. Peltz.  Understanding Our Drugs and Our Diseases.  Proceedings of the American Thoracic Society.  3: 409-412, 2006.

2005

Wang, J.; Liao,G.; Usuka, J.; Peltz, G.  Computational Genetics: From Mouse to Man? Trends in Genetics. 21: 526-532, 2005.

Wang,J.; Liao,G.; Chang,J.; Nguyen,A.; Guo,J.; Chou,S.; Hu,S.; Bach,C.; Allard,J.; Shafer,S.; Puech,A.; McPherson,J.D.; Foernzler,D.; Peltz,G.; Usuka,J.  Haplotypic Structure of the Mouse Genome.  Chapter 4 in Computational Genetics: New Tools for Disease Biology.  G. Peltz, editor. Trenton: Humana Press, 2005.

Peltz, G.  Computational Biology Are We There Yet? Chapter 1 in Computational Genetics: New Tools for Disease Biology.  G. Peltz, Editor. Trenton: Humana Press, 2005.

Wang, J., Peltz, G. Haplotype-Based Computationa Genetic Analysis in Mice. Chapter 3 in Computational Genetics: New Tools for Disease Biology.  G. Peltz, Editor. Trenton: Humana Press, 2005.

Usuka, J.; Peltz, G. From Mouse Genetics to Human Therapeutics.  Current Opinion in Drug Discovery and Development. 8: 253, 2005.

Moffett, S.P.; Zmuda, J.M.;  Oakley, J.M.; Beck, T.J.; Cauley, J.A.,Stone,K.L., Lui,L.Y.;Ensrud, K.E., Hillier,T.A., Hochberg, M.A.; Morin,P.; Peltz, G; Greene,D.; Cummings, S.R.Tumor Necrosis Factor Alpha Polymorphism, Bone Strength Phenotypes, and the Risk of Fracture in Older Women.  J. Clin. End. Metab. 90: 3492-3497, 2005.

Guo, Y.; Shafer, S.: Usuka, J.; Peltz, G. The Pharmacogenomic Road Ahead.  Pharmacogenetics.  6:857-864, 2005.

2004

Wang,J.; Liao,G.; Chang,J.; Nguyen,A.; Guo,J.; Chou,S.; Hu,S.; Allard,J.; Shafer,S.; Puech,A.; McPherson,J.D.; Foernzler,D.; Peltz,G.; Usuka,J.  In Silico Genetics: Identification of A Novel Functional Element Regulating H2-Ea Gene Expression.  Science 306:690-96, 2004.

Klein,R.F.; Alard,J.; Avnur,Z.; Nikolcheva,T.; Rotstein,D.; Carlos,A.S.; Shea,M.; Waters,R.V.; Belknap,J.K.; Peltz,G.; Orwoll,E.S.  Regulation of Bone Mass in Mice by the Lipoxygenase Gene Alox15Science.  303:229-232, 2004.

Savov, J.D., Whitehead,G.S., Foster,W.M.,Wang,J.,Liao,G., Usuka,J., Peltz,G., Schwartz,D.A.  O3-Induced Acute Pulmonary Injury in Inbred Mouse Strains.  Am. J. Resp. Cell Mol. Biol., 31: 69-77, 2004.

2000-2003

Karp,C.L.; Grupe,A.; Schadt,E.; Ewart,S.; Keane-Moore,M.; Cuomo,P.J; Kohl,J.; Wahl,L.; Kuperman,D.; Germer,S.; Aud,D.; Peltz,G.; Wills-Karp,M. Identification of Complement Factor 5 (C5) as a Susceptibility Factor for Experimental Allergic Asthma.  Nature Immunology. 1:221, 2000.

Grupe,A.; Germer,S.; Usuka,J; Aud,D.; Belknap,J.K.; Klein,R.F.; Ahluwalia,M.K.; Higuchi,R.; Peltz,G. In Silico Mapping of Complex Disease-Related Traits in Mice. Science.  292:1915, 2001.

Ewert,S.; Kuperman,D.; Schadt,E.; Tankersley,C.; Grupe,A.; Shubitowski,D.M.; Peltz,G.; Wills-Karp,M. Quantitative Trait Loci Controlling Allergen-Induced Airway Hyperresponsiveness in Inbred Mice. Am J Respir Cell Mol Biol.  23: 537-45, 2000.

Rozzo,S; Allard,J.D;Choubey,D; Vyse,T.;Izui,S.;Peltz,G.;Kotzin,B.L.  Evidence for an interferon-inducible gene, ifi202, in the susceptibility to Systemic Lupus.  Immunity.  15:1,2001.

Noble, J.A., White, Amy, M., Lazzeroni, L.C., Valdes, A.M., Mirel, D.B., Reynolds, R., Grupe, A., Aud, D., Peltz, G., Erlich, H.A. (2003).  A polymorphism in the TCF7 gene, C883A, is associated with type 1 diabetes. Diabetes. 52: 1579-82.

20th Century

Liu, H.-Y., Peltz, G.A., Leytus, S.P., Livingston, C., Brocklehurst, J., Mangel, W.F.. Sensitive assay for plasminogen activator of transformed cells. Proc. Natl. Acad. Sci (USA) 77:3796-800, 1980.

Mangel, W.F., Livingston, D.C., Brocklehurst, J.R., Liu, H.-Y., Peltz, G.A., Cannon, J.F., Leytus, S.P., Wehrly, J.A., Salter, B.L., Mosher, J.L. New assay for the plasminogen activator activity of transformed cells. Cold Spring Harbor Symposia on Quantitative Biology 44(1):669-80, 1980.

Mangel, W.F., Livingston, D.C., Brocklehurst, J.R., Cannon, J.F., Leytus, S.P., Peltz, S.W., Peltz, G.A., Liu, H.-Y. A new active-site titrant of serine proteases. Methods in Enzymology 80 Pt C:414-24, 1981.

Leytus, S.P., Peltz, G.A., Liu, H.-Y., Cannon, J.F., Peltz, S.W., Livingston, D.C., Brocklehurst, J.R., Mangel, W.F. A quantitative assay for the activation of plasminogen by transformed cells in situ and by urokinase. Biochemistry 20:4307-14, 1981.

Livingston, D.C., Brocklehurst, J.R., Cannon, J.F., Leytus, S.P., Wehrly, J.A., Peltz, S.W., Peltz, G.A., Mangel, W.F. Synthesis and characterization of a new fluorogenic active-site titrant of serine proteases. Biochemistry 20:4298-306, 1981.

Peltz, G., Kuczmarski, E. and J. Spudich.  Dictyostelium myosin: characterization of chymotryptic subfragments and localization of a heavy chain phosphorylation site.  J. Cell Biol. 89:104‑108, 1981.

Flicker, P., Peltz, G., Sheetz, M., Parham, P. and J. Spudich.  Site‑specific inhibition of myosin‑mediated motility in vitro by monoclonal antibodies.  J. Cell Biol. 100:1024‑1030, 1985.

Peltz, G., Spudich, J.A., Parham, P. Monoclonal antibodies against seven sites on the head and tail of Dictyostelium myosin. The Journal of Cell Biology 100:1016-23,1985.

Peltz, G.A., Gallis, B., Peterlin, B.M. Monoclonal antibody immunoprecipitation of cell membrane glycoproteins. Analytical Biochemistry 167:239-44, 1987.

Peltz, G., Trounstein, M. and K. Moore.  Cloned and expressed human Fc RII mediates anti‑CD3 induced lymphoproliferation.  J. Immunol. 141:1891‑1896, 1988.

Grundy, H.O., Peltz, G., Moore, K.W., Golbus, M.S., Jackson, L.G., Lebo, R.V. The polymorphic Fc gamma receptor II gene maps to human chromosome 1q. Immunogenetics29:331-9,1989.

Peltz, G., Grundy, H., Lebo, R., Yssel, H., Barsh, G. and K. Moore.  Human Fc RIII: cloning, expression and identification of the chromosomal locus of two Fc receptors for IgG.  Proc. Natl. Acad. Sci. 86:1013‑1017, 1989. 

Peltz, G., Frederick, K., Anderson, C.L., Peterlin-B.M. Characterization of the human monocyte high affinity Fc receptor (hu FcRI). Molecular immunology 25:243-50,1988.

Trounstine, M.L., Peltz, G.A., Yssel, H., Huizinga, T.W., von dem Borne,A.E., Spits, H., Moore, K.W. Reactivity of cloned, expressed human Fc gamma RIII isoforms with monoclonal antibodies which distinguish cell-type-specific and allelic forms of Fc gamma RIII.  International Immunology 2:303-10, 1990.

Mensi, N., Webb, D.R., Turck, C.W., Peltz, G.A.  Characterization of Borrelia burgdorferi proteins reactive with antibodies in synovial fluid of a patient with Lyme arthritis. Infection and Immunity 58:2404-7, 1990.

Yssel, H., Nakamoto, T., Schneider, P., Freitas, V., Collins, C., Webb, D., Mensi, N., Soderberg, C., Peltz, G. Analysis of T lymphocytes cloned from the synovial fluid and blood of a patient with Lyme arthritis. International Immunology 2:1081-9,1990.

Yssel, H., Shanafelt, M.-C., Soderberg, C., Schneider, P., Anzola, J., and G. Peltz.  B. burgdorferi activates a TH1-like T cell subset in Lyme arthritisJ. Exp. Med. 174:593-601, 1991.

Shanafelt, M.C., Hindersson, P., Soderberg, C., Mensi, N., Turck, C.W., Webb, D., Yssel, H., Peltz, G.   T cell and antibody reactivity with the Borrelia burgdorferi 60-kDa heat shock protein in Lyme arthritis.  Journal of Immunology 146: 3985-92, 1991.

Peltz, G. A role for CD4+ T cell subsets producing a selective pattern of lymphokines in the pathogenesis of human chronic inflammatory and allergic diseases. Immunol. Rev. 123:23-35, 1991.

Collins, C., Peltz, G.  Immunoreactive epitopes on an expressed recombinant flagellar protein of Borrelia burgdorferi. Infection and Immunity 59:514-20, 1991.

Shanafelt, M.C.,  Anzola, J., Soderberg, C., Yssel, H., Turck, C., and G. Peltz. Epitopes on the outer surface protein A of Borrelia burgodorferi recognized by antibodies and T cells of Lyme arthritis patients.  J. Immunol. 146:3985-3992, 1992.

Anzola, J., Luft, B.J., Gorgone, G., Peltz, G. Characterization of a Borrelia burgdorferi dnaJ homolog. Infection and Immunity 60:4965-8, 1992.

Anzola, J., Luft, B.J., Gorgone, Dattwyler, R.J., Soderberg C., Lahesmaa, R., Peltz, G. Borrelia burgdorferi HSP70 homolog: characterization of an immunoreactive stress protein. Infection and Immunity 60:3704-13 1992.

Lahesmaa, R., Yssel, H., Batsford, S., Luukkainen, R., Möttönen, T., Steinman, L., Peltz, G.
Yersinia enterocolitica activates a T helper type 1-like T cell subset in reactive arthritis.  Journal of Immunology 148:3079-85, 1992.

Lahesmaa, R, Shanafelt, M.C., Steinman, L., Peltz, G.  Immunopathogenesis of human inflammatory arthritis: lessons from Lyme and reactive arthritis. J. Inf. Dis. 170:978-85, 1994.

Begovich, A.B., Klitz, W., Moonsamy, P.V., Van de Water J., Peltz, G., Gershwin, M.E. Genes within the HLA class II region confer both predisposition and resistance to primary biliary cirrhosis. Tissue Antigens 43: 71-7, 1994.

Lahesmaa, R., Soderberg, C., Bliska, J., Leirisalo-Repo, M., Luukkainen, R., Steinman, L., and G. Peltz. Pathogen antigen and superantigen-responsive T cells in reactive arthritis. J. Inf. Dis.  172:1290-97, 1995.

Shanafelt, M-C., Soderberg, C., Allsup, A., Adelman, D., Peltz, G., and Lahesmaa, R. Costimulatory signals can selectively modulate cytokine production by CD4+ T cells.  J. Immunol.  154:1684-90, 1995.

Jackman, J., Motto, D., Sun, Q., Tanemoto, M., Turck,C.W., Peltz, G.A., Koretzky, G.A., Findell, P.R.  Molecular  cloning of SLP76, a 76 kDa tyrosine phosphoprotein associated with Grb2 in T cells.  J. Biol. Chem. 240:2029-32, 1995.

Lahesmaa, R., Shanafelt, M.C., Allsup, A., Soderberg, C., Anzola, J., Freitas, V., Turck, C., Steinman, L., Peltz, G.  Preferential usage of T cell antigen receptor V region gene segment V beta 5.1 by Borrelia burgdorferi antigen-reactive T cell clones isolated from a patient with Lyme disease.  Journal of Immunology 150: 4125-35, 1993.

Shanafelt, M-C., Yssel, H.,  Soderberg, C., Steinman, L., Adelman, D., Peltz, G., and R. Lahesmaa.  CD45 isoforms on human T cell subsets.  J. Allergy Clin. Immunol. 98:433-40, 1996.

Lahesmaa,R., Allsup,A., Soderberg, C., Jackman, J., Findell, P., and G. Peltz.  Modulation of the grb2-associated protein complex in human CD4+ Tcells by receptor activation. J. Immunol. 155:3815-22, 1995.

Turcovski-Corrales,S.M., Fenton, R.G., Peltz., G, Taub, D.D. CD28:B7 interactions promote T cell adhesion. European Journal of Immunology 25:3087-93,1995.

Peltz,G.  Transcription factors in immune-mediated disease.  Current Opin. Biotech. 8:467-73, 1997.

Ranganath S. Ouyang WJ. Bhattarcharya D. Sha WC. Grupe A. Peltz G. Murphy KM (1998) Gata-3-dependent enhancer activity in IL-4 gene regulation. Journal of Immunology161, 3822-3826.

Guler ML. Gorham JD. Dietrich WF. Murphy TL. Steen RG. Parvin CA. Fenoglio D. Grupe A. Peltz G. Murphy KM. (1999) Tpm1, a locus controlling IL-12 responsiveness, acts by a cell-autonomous mechanism. Journal of Immunology 162, 1339-1347.

Ranganath,S.; Ouyang,W.; Bhattarcharya,D.; Sha,W.C.; Grupe,A.; Peltz,G.; Murphy,K.M. GATA-3-dependent enhancer activity in IL-4 gene regulation.  J. Immunol.   161:3822-26,1998.

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