8:00 AM - 9:00 AM
Pediatric Grand Rounds (CME) - New Therapies and Diagnostics for Cardiac Arrest and Traumatic Brain Injury: Studies from the Safar Center for Resuscitation Research
Patrick Kochanek, MD, MCCM - University of Pittsburgh
In this lecture, we will provide a summary of recent studies from investigators in the Safar Center for Resuscitation Research at the UPMC Children’s Hospital of Pittsburgh. Translational investigations at the Safar Center are focused on pediatric neurocritical care and resuscitation research targeting new therapy and biomarker development for both cardiac arrest and traumatic brain injury.
Patrick Kochanek, MD, MCCM
Professor of Critical Care Medicine, Anesthesiology and Pediatrics
Ake N. Grenvik Endowed Chair in Critical Care Medicine
Director, Safar Center for Resuscitation Research
Director, Training in Pediatric Neurointensive Care and Resuscitation Research
In this lecture a summary of recent studies from investigators in the Safar Center for Resuscitation Research at the UPMC Children’s Hospital of Pittsburgh will be provided. Translational investigations at the Safar Center are focused on pediatric neurocritical care and resuscitation research targeting new therapy and biomarker development for both cardiac arrest and traumatic brain injury. Research spanning bench and bedside will be presented across the continuum of care from the field through the ICU and rehabilitation. Key topics of investigation include novel approaches targeting cerebral edema, oxidative stress, and mitochondrial failure, strategies to develop phenotype-based therapies for both traumatic brain injury and cardiac arrest, the development of serum biomarkers for diagnostic, prognostic, and theranostic applications in neurocritical care, and novel investigations that are being developed to enhance the neuroprotective potential of therapeutic hypothermia through an enhanced understanding of its molecular underpinnings.
- To become familiar with new treatments being developed for severe traumatic brain injury in children
- To understand the role of therapeutic hypothermia in cerebral resuscitation and become aware of novel potential adjuncts to improve its efficacy.
- To recognize new therapies that are being tested to prevent the development of cerebral edema across the spectrum of acute brain injury
- To understand the role of hypoperfusion in secondary brain injury after cardiac arrest and become familiar with new potential therapies to improve cerebral perfusion.
Lucile Packard Children's Hospital, West Building Auditorium725 Welch Road
Stanford CA, 94304
The Stanford University School of Medicine is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
The Stanford University School of Medicine designates this live activity for a maximum of 1.00 AMA PRA Category 1 Credit(s)TM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Cultural and Linguistic Competency
California Assembly Bill 1195 requires continuing medical education activities with patient care components to include curriculum in the subjects of cultural and linguistic competency. The planners and speakers of this CME activity have been encouraged to address cultural issues relevant to their topic area. The Stanford University School of Medicine Multicultural Health Portal also contains many useful cultural and linguistic competency tools including culture guides, language access information and pertinent state and federal laws. You are encouraged to visit the portal: http://lane.stanford.edu/portals/cultural.html
Planner and Faculty Disclosure to Learners
In accordance with the standards of the Accreditation Council for Continuing Medical Education (ACCME), all speakers, planners and/or persons who can influence the CME content must disclose to learners any relationships with commercial interests providing products or services that are relevant to the content of the presentation. The following individual(s) HAVE indicated the following relationships:
Bertil Glader, MD
Contracted Research: Agios
The following speakers, planning committee members and/or persons who can influence CME content have indicated they have NO relationships with commercial industry to disclose relevant to the content of this CME activity:
Alan Schroeder, MD, Associate Chief for Research, Division of Pediatric Hospital Medicine
Mary Leonard, MD, MSCE, Chair Department of Pediatrics
Matthew Porteus, MD, PhD, Associate Professor, Division of Stem Cell Transplantation and Regenerative Medicine
Neville H. Golden, MD, Chief, Division of Adolescent Medicine
Lisa Chamberlain, MD, MPH, Associate Professor, General Pediatrics
Minnie Dasgupta, MD, Chief Resident, Pediatric Residency Program
Patrick Kochanek, MD, MCCM