Research & Quality


We are committed to developing clinician scientists and clinician educators and ensure that all of our fellows are actively engaged in the scientific discovery process throughout their fellowship. Fellows begin by identifying a research mentor and project in their first 6 months of fellowship training.

Unique and Flexible Opportunities for Dual Training

We strive to help fellows identify their passions and then work to provide the mentorship and resources to enable their success. 

We also take pride in being creative and have facilitated combined advanced training for many fellows. These have taken advantage of many of the amazing opportunities available at Stanford and beyond. Recent examples have included:

- Opportunities to spend months abroad for global health (even during the first year of training) (Ali Arastu-India, Class of 2020, Matt Marx and Zack Smith, Class of 2022)

Other possibilities include PCCM-peds oncology, PCCM-peds anesthesia, PCCM-neurocritical care, PCCM-Bioethics, amongst many others.

Our PCCM fellows are diverse in their scholarly interests! Read their bios below to appreciate the scope of their interests, scholarly research and quality improvement endeavors, and funding sources. Fellows have presented their research at national scientific meetings held by the Pediatric Academic Societies, American Academy of Pediatrics, the Society of Critical Care Medicine, the American Thoracic Society, Pediatric Cardiac Intensive Care Society, and the Pediatric Critical Care World Congress. 

Our faculty members have mentored fellows in basic science and translational research projects, global health, quality improvement, and palliative care research. 

Senior Faculty Basic Science programs: 

-       Investigation of the role of BFKB in pulmonary angiogenesis and vascularization, discovering novel proteins in the developing lung secretome - Alvira Lab

-       Investigation of pulmonary vascular tone regulation and oxygen sensing, regulation of pulmonary barrier functions, understanding the role of hypoxia-inducible factor-1 in lung development - Cornfield Lab 

-       Elucidating the mechanisms and management of opioid-induced tolerance/withdrawal, and developing novel measures of chronic stress - Anand Lab

Clinical and translational research programs including:

     - Clinical pharmacology and pharmacometrics 

     - REVIVE resuscitation and simulation

     - Solid organ transplantation 

     - Biomedical informatics

     - Global health initiatives

     - Quality and process improvement

     - Palliative care and BioEthics

Stanford Programs our PCCM Fellows have participated in during fellowship: 

     - Clinical Effectiveness Leadership Training Program

     - Intensive Course in Clinical Research 

     - Biodesign Innovation Fellowship 

     - Clinical Excellence Research Center Design Fellowship

     - Stanford Society of Physician Scholars

     - Masters Program in Health Research and Policy

     - Stanford EM Ultrasound Fellowship

Other Research Opportunities available to PCCM Fellows: 

The PCCM division is nested in a renowned Children's Hospital, at a leading Medical School and a premier University - thereby allowing unparalleled opportunities for research and collaboration, with access to distinguished mentors in every field for our PCCM fellows.

The Stanford Center for Clinical and Translational Research and Education sponsors a variety of mentored career development and research training programs including an NIH KL2. The Department of Pediatrics offers competitive Masters Degree Programs (Education, Health Research Policy, Biomedical Informatics, Epidemiology & Clinical Research, Community Health & Prevention Research). The PCCM Division is also involved in multi-center clinical trials in collaboration with the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) network and other leading research groups. 

The Department of Pediatrics at Stanford University creates a comprehensive research training program designed to provide outstanding training to prepare our fellows to excel as sub-specialty clinicians, researchers, teachers, and become leaders within the field of pediatrics. More information regarding these programs can be found on the Department of Pediatrics website: https://med.stanford.edu/pedsfellowships.html

Pediatric Critical Care Fellows

Sherry Gu, MD

"Comprehensive Genotype-Phenotype Analysis of Patients with TOF/PA/MAPCAs"

Presentations:

  • Singh, D., Dyer, A., Gu, S.; McCarville, P., Hess, A., Akingbola, O., El-Dahr, J., Nelson, S. (April 19th, 2017).  An Unusual Cause of Frequent, Sudden, Transient, Unexplained Falls and New-Onset Status Epilepticus: Case Report and Mini-Review. Clinical Pediatrics.
  • Gu, S., Barbiero, L., Nelson, S.  The Trouble with Letting Go: Neonate with Hypotonia. Presenting at Southern Regional Meeting. February 22nd 2018.
  • Gu, S., Nelson, S. Hashimoto’s Encephalopathy—When to consider? Presented at Southern Regional Meeting. February 11th 2017
  • Gu, S., Carroll, V. A New Player in Lemierre’s. Presented at The Pediatric Hospital Medicine Meeting. July 22, 2017.
  • Gu, S., Glaug, N., Cnaan, A., Packer R., Avery R. (March 10, 2014). Ganglion cell layer-inner plexiform layer thickness and vision loss in young children with optic pathway gliomas.Investigative Ophthalmology & Visual Science,  55(3), 1402-1408.
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Hannah Canty, MD

"Quantifying the Number of Patients Affected with Pediatric Post Intensive Care Syndrome and Parents' Perspectives on How to Mitigate its Development"

Publications:

Canty HR, Sauter A, Zuckerman K, Cobian M, Grigsby T. Mothers’ perspectives on follow-up for postpartum depression screening in primary care. J Dev Behavior Pediatr. 2018.

Presentations:

Canty, H.R., McDermott-Burnside, G., Sanders, L. (2020, Feb). Family Characteristics associated with PTSD in children and caregivers after PICU admission. Work in Progress Presentation American Pediatric Association Regions 9 & 10 Meeting, Monterey. 

Sub-Group Presentation Pediatric Acute Lung Injury and Sepsis Investigators, New Orleans.

Poster Presentation Pediatric Academic Societies.

Amrita Sinha, MD

"Reliability and Validity of the CLOC time: A Novel EHR Metric to Indicate Physician Burnout"

Publications:

Amrita Sinha MD, Maroun Mhanna MD MPH, Reema Gulati MD. Clinical Characteristics of Children Needing Inpatient Treatment after Failed Outpatient Treatment for Fecal Impaction. Pediatr Gastroenterol Hepatol Nutr. 2018 Jul;21(3):196-202. doi: 10.5223/pghn.2019.21.3.196. Epub 2018 Jun 28. . Department of Pediatrics, MetroHealth Medical Center (MHMC), Case Western Reserve University, Cleveland.

Natalie Wilson, MD

"Risk of Delirium in PICU Patients With a Change in Functional Outcome During Admission"

Presentations:

Clinical Conundrums "An ImPRESsive Case of Glomerulonphritis" Pediatric Hosptialist Medicine Conference, Chicago, IL. July 30, 2018.

“Simulation-based Curriculum to Improve Central Venous Line Preparation and Placement Times” Oral Abstract Presentation Association of Pediatric Program Directors San Diego, CA (2020)

“Measuring Outcomes in Critically-ill Children: Implementation of a Functional Outcome Score as Standard of Care” Poster Presentation Pediatric Academic Societies Philadelphia, PA (2020)

Thomas LaRocca, MD, PhD

"Elucidation of the Role of Cardiac Myocyte mAKAPβ-SIK1 Signalosome on Pathological Remodeling Mechanisms in Murine Models of Heart Failure"

LaRocca TJ,  Beyersdorf, G., Li, W.,  Foltz, R., Patel, A., Tanel, RE. Distinct Electrophysiologic Profiles in  Pediatric Patients with Incidentally Identified Pre-excitation Compared to Wolff-Parkinson-White Syndrome.  American Journal of Cardiology, Accepted.  May 2019

LaRocca TJ, Altman P, Jarrah AA, Gordon R, Wang E, Hadri L, Burke MW, Haddad GE, Hajjar RJ, Tarzami ST.  CXCR4 Cardiac Specific Knock-out Mice Develop a Progressive Dilated Cardiomyopathy. Int J Mol Sci. 2019 May 8;20(9)

LaRocca TJ,  Arias, T. Mukete, B., Wu, J., Hajjar RJ. Lebeche, D., Karakikes, I. Pharmacological Silencing of Micro-RNA 152 protects the heart from pressure overload induced heart failure.   Submitted: Journal of American Heart Association, May  2019. 

Jarrah AA, Schwarskopf M, Wang ER, LaRocca T, Dhume A, Zhang S, Hadri L, Hajjar RJ, Schecter AD, Tarzami ST.  SDF-1 induces TNF-mediated apoptosis in cardiac myocytes. Apoptosis. 2018 Jan;23(1):79-91 

 

Zachary Smith, MD

"Mixed-Methods Evaluation of an mHealth Adaptive Learning Training Module for Pediatric Healthcare Workers in Tanzania"

Publications:

Bjornstad EC, Muronya W, Kamija M, Smith ZH, Munthali CK, Gibson K, Mottl AK, Charles A, Marshall SW, Golightly YM, Gower EW. Validity of Urine NGALds® Dipstick for Acute Kidney Injury in a Malawian Trauma Cohort. Kidney International Reports. 2020. Accepted.

Bjornstad EC, Muronya W, Smith ZH, Gibson K, Mottl AK, Charles A, Marshall SW, Golightly YM, Munthali CK, Gower EW. Incidence and epidemiology of acute kidney injury in a pediatric Malawian trauma cohort: a prospective observational study. BMC Nephrology. 2020 Mar 14.

Presentations:

“Digital Auscultation and Computerized Lung Sound Analysis for the Evaluation of Pediatric Pneumonia: Fogarty Global Health Postdoctoral Research Presentation” Fogarty International Center; National Heart, Lung, and Blood Institute National Institutes of Health Bethesda, MD

“Evidence-Based Guidelines for Paediatric Shock in LMICs.” Bugando Medical Center Department of Paediatrics Mwanza, Tanzania

Monica Ruiz, MD, MPH

"Pediatric Anxiety and Cortisol concentrations from Experiencing Stress (PACES): Hair cortisol concentration (HCC) as a biomarker of anxiety in immigrant and non-immigrant children"

Publications:

Marcela Lopez, Monica O. Ruiz, Cynthia R. Rovnaghi, Grace K-Y. Tam, Jitka Hiscox, Donald A. Barr, Ian H. Gotlib, Victor G. Carrion, Kanwaljeet J. S. Anand. The Social Ecology of Childhood and Early Life Adversity. Pediatric Research (Currently under review). June 2020.

Cynthia R. Rovnaghi, MS. ; Joseph Rigdon, PhD.; Jean-Michel Roué MD, PhD.; Monica O. Ruiz, MD, MPH; Kanwaljeet J. S. Anand, MBBS, D. Phil. Longitudinal Trajectories of Hair Cortisol to Assess HPA-Axis Function in Early Childhood. Psychoneuroendocrinology (Revisions under review). May 2020.

Elizabeth Dowart, DO

"Analysis of a PICU to ED Audiovisual Telemedicine Intervention on Risk of Mortality as measured by PIM2/3 scores."

Presentations:

Dorwart E, Marcin J, Su F, Wen A, et al. The Impact of PICU to ED Telemedicine on Changes in Severity of Illness. Abstract submitted to SEARCH telehealth conference. (2020).

Ghassemzadeh R, Dorwart E, Knight L, Berg, M. In Situ Mock Codes in the PICU during low census seasons. IPSSW. Toronto, CAN (2019)

Anne Durstenfeld, MD

"Prevalence of Anemia in Infants in Rural Sichuan and Association with Health-seeking Behavior"

Presentations:

Bochner R, Duh-Leong C, Durstenfeld A, Rabin M. Poster Presentation. The PRICE is Right: The Impact of the Pediatric Residents Improving Cost-Effectiveness (PRICE) Workshop. Architecture of High Value Healthcare National Conference, Baltimore, November 2019.