Recent Faculty Publications
2019 Publications
Allergy / Immunology
Gernez Y, de Jesus AA, Alsaleem H, Macaubas C, Roy A, Lovell D, Jagadeesh KA, Alehashemi S, Erdman L, Grimley M, Talarico S, Bacchetta R, Lewis DB, Canna SW, Laxer RM, Mellins ED, Goldbach-Mansky R, Weinacht KG. Severe autoinflammation in 4 patients with C-terminal variants in cell division control protein 42 homolog (CDC42) successfully treated with IL-1β inhibition. J Allergy Clin Immunol. 2019 Jul 2. pii: S0091-6749(19)30830-9. doi: 10.1016/j.jaci.2019.06.017. [Epub ahead of print]
Forrest OA, Chopyk DM, Gernez Y, Brown MR, Conrad CK, Moss RB, Tangpricha V, Peng L, Tirouvanziam R. Resistin is elevated in cystic fibrosis sputum and correlates negatively with lung function. J Cyst Fibros. 2019 Jan;18(1):64-70. doi: 10.1016/j.jcf.2018.05.018. Epub 2018 Jun 21.PMID: 29937317
Farmer JR, Foldvari Z, Ujhazi B, De Ravin SS, Chen K, Bleesing JJH, Schuetz C, Al-Herz W, Abraham RS, Joshi AY, Costa-Carvalho BT, Buchbinder D, Booth C, Reiff A, Ferguson PJ, Aghamohammadi A, Abolhassani H, Puck JM, Adeli M, Cancrini C, Palma P, Bertaina A, Locatelli F, Di Matteo G, Geha RS, Kanariou MG, Lycopoulou L, Tzanoudaki M, Sleasman JW, Parikh S, Pinero G, Fischer BM, Dbaibo G, Unal E, Patiroglu T, Karakukcu M, Al-Saad KK, Dilley MA, Pai SY, Dutmer CM, Gelfand EW, Geier CB, Eibl MM, Wolf HM, Henderson LA, Hazen MM, Bonfim C, Wolska-Kuśnierz B, Butte MJ, Hernandez JD, Nicholas SK, Stepensky P, Chandrakasan S, Miano M, Westermann-Clark E, Goda V, Kriván G, Holland SM, Fadugba O, Henrickson SE, Ozen A, Karakoc-Aydiner E, Baris S, Kiykim A, Bredius R, Hoeger B, Boztug K, Pashchenko O, Neven B, Moshous D, Villartay JP, Bousfiha AA, Hill HR, Notarangelo LD, Walter JE. Outcomes and Treatment Strategies for Autoimmunity and Hyperinflammation in Patients with RAG Deficiency. J Allergy Clin Immunol Pract. 2019 Jul-Aug;7(6):1970-1985.e4. doi: 10.1016/j.jaip.2019.02.038. Epub 2019 Mar 12.PMID: 30877075
Ghaemi MS, DiGiulio DB, Contrepois K, Callahan B, Ngo TTM, Lee-McMullen B, Lehallier B, Robaczewska A, Mcilwain D, Rosenberg-Hasson Y, Wong RJ, Quaintance C, Culos A, Stanley N, Tanada A, Tsai A, Gaudilliere D, Ganio E, Han X, Ando K, McNeil L, Tingle M, Wise P, Maric I, Sirota M, Wyss-Coray T, Winn VD, Druzin ML, Gibbs R, Darmstadt GL, Lewis DB, Partovi Nia V, Agard B, Tibshirani R, Nolan G, Snyder MP, Relman DA, Quake SR, Shaw GM, Stevenson DK, Angst MS, Gaudilliere B, Aghaeepour N. Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy. Bioinformatics. 2019 Jan 1;35(1):95-103. doi: 10.1093/bioinformatics/bty537. PMID: 30561547
Handumrongkul C, Ye AL, Chmura SA, Soroceanu L, Mack M, Ice RJ, Thistle R, Myers M, Ursu SJ, Liu Y, Kashani-Sabet M, Heath TD, Liggitt D, Lewis DB, Debs R. Durable multitransgene expression in vivo using systemic, nonviral DNA delivery. Sci Adv. 2019 Nov 27;5(11):eaax0217. doi: 10.1126/sciadv.aax0217. eCollection 2019 Nov. PMID: 31807699
Lippner EA, Lewis DB, Robinson WH, Katsumoto TR. Paraneoplastic and Therapy-Related Immune Complications in Thymic Malignancies. Curr Treat Options Oncol.20:62, 2019. doi: 10.1007/s11864-019-0661-2.
Huffaker M*, Liu AY*, Enns G, Vijay S, Amor AJ, Adkinson NF. Case series of sebelipase alfa hypersensitivity reactions and successful sebelipase alfa rapid desensitization. JIMD (J of Inherited Metabolic Diseases) Reports. 2019 Aug 1. 49(1):30-36. PMID: 31497479. Co-First Author
Multani A, Subramanian A, Liu AY. Successful eradication of chronic symptomatic Candida krusei urinary tract infection with increased dose micafungin in a liver and kidney transplant recipient: Case report and review of the literature. Transplant Infectious Disease. 2019 Aug; 21(4): e13118. PMID: 31111613.
Lo R, Alexander S, Moss J, Siddiqi A, Liu A. Eculizumab hypersensitivity and desensitization in a toddler with atypical hemolytic uremic syndrome. Journal of Allergy and Clinical Immunology: In Practice. 2019 Sept-Oct. 7(7):2409-2410. PMID: 30946976.
Multani A, Rustagi A, Epstein DJ, Gomez CA, Budvytiene I, Banaei N, Brown JM, Liu AY. Diagnostic Microbiology and Infectious Disease. 2019 Sep. 92(1):77-79. PMID: 31005402.
Rheumatology
Chan A, Frankovich J. Infections, Antibiotics, and Mental Health Deteriorations. J Child Adolesc Psychopharmacol. 2019 Oct;29(8):647-648. doi: 10.1089/cap.2019.0100. Epub 2019 Jul 29. PMID:31355667
Silverman M, Frankovich J, Nguyen E, Leibold C, Yoon J, Mark Freeman G, Karpel H, Thienemann M. Psychotic symptoms in youth with Pediatric Acute-onset Neuropsychiatric Syndrome (PANS) may reflect syndrome severity and heterogeneity. J of Psychiatric Research. 2019 March Vol 110 93-102. DOI: 10.1016/j.jpsychires.2018.11.013
Knight A, Vickery M, Faust L, Muscal E, Davis A, Harris J, Hersh AO, Rodriguez M, Onel K, Rubinstein T, Washington N, Weitzman ER, Conlon H, Woo JMP, Gerstbacher D, von Scheven E; Gaps in Mental Health Care for Youth With Rheumatologic Conditions: A Mixed Methods Study of Perspectives From Behavioral Health Providers. Childhood Arthritis and Rheumatology Research Alliance Investigators. Arthritis Care Res (Hoboken). 2019 May;71(5):591-601. doi: 10.1002/acr.23683. Epub 2019 Apr 8. PMID: 29953741
DiAngi YT, Stevens LA, Halpern-Felsher B, Pageler NM, Lee TC. Electronic health record (EHR) training program identifies a new tool to quantify the EHR time burden and improves providers' perceived control over their workload in the EHR. JAMIA Open. 2019;2(2):222‐230. Published 2019 Mar 21. doi:10.1093/jamiaopen/ooz003
Smitherman EA.Huang B, Laxer R, April Bingham C, Yildirim-Toruner C, Gottlieb B, Weiss J E, Lee T, Vora S, Burnham J, Harris J, Olson J, Gilbert M, Batthish M, Shishov M, Fleck D, Morgan E. FRI0550 JIA Disease Activity Outcomes Across A Multi-Center Cohort: Analysis of The Pediatric Rheumatology Care and Outcomes Improvement Network (PR-COIN) Registry. Annals of the Rheumatic Diseases 2019;78:970-971.
Ma M, Hui-Yuen JS, Cerise JE, Iqbal S, Eberhard BA. Validation of the 2017 Weighted criteria compared to the 1997 ACR and the 2012 SLICC in Pediatric Systemic Lupus Erythematosus [published online ahead of print, 2019 Sep 3]. Arthritis Care Res (Hoboken). 2019;10.1002/acr.24057. doi:10.1002/acr.24057
Impact Factor: 4.056
Shanafelt T, Trockel M, Ripp J, Murphy ML, Sandborg C, Bohman B. Building a Program on Well-Being: Key Design Considerations to Meet the Unique Needs of Each Organization Acad Med. 2019 Feb;94(2):156-161. doi: 10.1097/ACM.0000000000002415.PMID: 30134268
Leibold C, Thienemann M, Farhadian B, Willett T, Frankovich J. Psychometric Properties of the Pediatric Acute-Onset Neuropsychiatric Syndrome Global Impairment Score in Children and Adolescents with Pediatric Acute-Onset Neuropsychiatric Syndrome. Journal of Child and Adolescent Psychopharmacology. 2019 Feb;29(1):41-49. doi: 10.1089/cap.2018.0029
2017/2018 Publications
Allergy / Immunology
Gernez Y, Baker MG, Maglione PJ. Humoral immunodeficiencies: conferred risk of infections and benefits of immunoglobulin replacement therapy. Transfusion. 2018 Dec;58 Suppl 3:3056-3064. doi: 10.1111/trf.15020. Review. PMID:30536429
Gernez Y, Sicherer SH, Wang J. Variability in diagnosis and management of acquired cold-induced urticaria.
J Allergy Clin Immunol Pract. 2018 Jul - Aug;6(4):1396-1399. doi: 10.1016/j.jaip.2017.12.030. Epub 2018 Mar 9. No abstract available. PMID:29530343
Gernez Y, Freeman AF, Holland SM, Garabedian E, Patel NC, Puck JM, Sullivan KE, Akhter J, Secord E, Chen K, Buckley R, Haddad E, Ochs HD, Fuleihan R, Routes J, Muskat M, Lugar P, Mancini J, Cunningham-Rundles C.
Autosomal Dominant Hyper-IgE Syndrome in the USIDNET Registry. J Allergy Clin Immunol Pract. 2018 May - Jun;6(3):996-1001. doi: 10.1016/j.jaip.2017.06.041. Epub 2017 Sep 19. PMID:28939137
Rosa JS, Hernandez JD, Sherr JA, Smith BM, Brown KD, Farhadian B, Mahony T, McGhee SA, Lewis DB, Thienemann M, Frankovich JD. Allergic Diseases and Immune-Mediated Food Disorders in Pediatric Acute-Onset Neuropsychiatric Syndrome. Pediatr Allergy Immunol Pulmonol. 2018 Sep 1;31(3):158-165. doi: 10.1089/ped.2018.0888. Epub 2018 Sep 17. PMID: 30283713
Choi DH, Chmura SA, Ramachandran V, Dionis-Petersen KY, Kobayashi Y, Nishi T, Luikart H, Dimbil S, Kobashigawa J, Khush K, Lewis DB, Fearon WF. The ratio of circulating regulatory cluster of differentiation 4 T cells to endothelial progenitor cells predicts clinically significant acute rejection after heart transplantation. J Heart Lung Transplant. 2018 Apr;37(4):496-502. doi: 10.1016/j.healun.2017.10.012. Epub 2017 Oct 22. PMID: 29198869
Weitkamp J.-H., Lewis, D.B., Levy O. Chapter 36, Immunology of the fetus and newborn. In: Avery’s Diseases of the Newborn, 10th edition, edited by C.A. Gleason and S.E. Juul, Elsevier, 2018.
Rosa JS, Vuong VB, Haskin O, Liu AY. A novel outpatient desensitization protocol for recombinant human erythropoietin allergy in a pediatric patient. Allergy, Asthma, and Clinical Immunology. 2018 Mar. 14:8. PMID: 29545827. (2.664)
Benamu E, Yu AT, Xie L, Fernandez-Pol S, Liu AY, Ho DY. Scedosporium apiospermum infection of the urinary system with a review of treatment options and cases in the literature. Transplant Infectious Diseases. 2018 Feb. 20(1). PMID 29111602. (2.112) Contributed to case report development and editing.
McGhee SA. Biologics in pediatric lung disease. Curr Opin Pediatr. 2018 Jun;30(3):366-371. doi: 10.1097/MOP.0000000000000614. Review. PubMed PMID: 29538045. Impact Factor 2.333
Postolova A, Bradley JT, Parris D, Sherr J, McGhee SA, Hernandez JD. Anaphylaxis to invasive chlorhexidine administration despite tolerance of topical chlorhexidine use. J Allergy Clin Immunol Pract. 2018 May - Jun;6(3):1067-1069.e1. doi: 10.1016/j.jaip.2017.11.001. Epub 2017 Dec 7. PubMed PMID: 29226805.
Huffaker MF, McGhee SA. Four cases of delayed onset systemic reaction to shellfish. J Allergy Clin Immunol Pract. 2018 Mar - Apr;6(2):656-657. doi: 10.1016/j.jaip.2017.06.004. Epub 2017 Jul 19. PubMed PMID: 28734856.
Rheumatology
Klecka, M., Thybo, C., Macaubas, C., Solov'yov, I., Simard, J., Balboni, I., Fox, E., Voss, A., Mellins, E. D., Astakhova, K. Autoantibody Profiling in Lupus Patients using Synthetic Nucleic Acids.Scientific Reports. 2018 April; 8 (5554). doi:https://doi.org/10.1038/s41598-018-23910-5 PubMed PMID:29615791
Favier LA, Taylor J, Loiselle Rich K, Jones KB, Vora SS, Harris JG, Gottlieb BS, Robbins L, Lai JT, Lee T, Kohlheim, Gill J, Bouslaugh L, Young A, Griffin N, Morgan EM, Modi AC. Barriers to Adherence in Juvenile Idiopathic Arthritis: A Multicenter Collaborative Experience and Preliminary Results.Journal of Rheumatology. 2018 May;45(5):690-696. doi: 10.3899/jrheum.171087. Epub 2018 Feb 1. PubMed PMID:29419467
Bingham CA, Pratt J, Yildirim-Toruner C, Laxer R, Gottlieb B, Weiss J, Lee T, Vora SS, Burnham J, Harris J, Olson JC, Passo M, Batthish M, Shishov M, Ferraro K, Levy DM, O'Brien C, Whitney-Mahoney K, Griffin N, Paul A, Morgan E. Pediatric Rheumatology Care and Outcomes Improvement Network Demonstrates Improvement on Quality Measures for Children with Juvenile Idiopathic Arthritis [abstract]. Arthritis Rheumatol. 2017; 69 (suppl 4). https://acrabstracts.org/abstract/pediatric-rheumatology-care-and-outcomes-improvement-network-demonstrates-improvement-on-quality-measures-for-children-with-juvenile-idiopathic-arthritis-2/. Accessed September 7, 2018.
Frankovich J, Leibold CM, Farmer C, Sainani K, Kamalani G, Farhadian B, Willett T, Park JM, Sidell D, Ahmed S, Thienemann M. The Burden of Caring for a Child or Adolescent With Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS): An Observational Longitudinal Study. J Clin Psychiatry. 2018 Dec 11;80(1). pii: 17m12091. doi: 10.4088/JCP.17m12091.
O'Gorman, W.E., Kong, D.S., Balboni, I.M., Rudra, P., Bolen, C.R., Ghosh, D., Davis, M.M., Nolan, G.P., & Hsieh, E.W. (2017). Mass cytometry identifies a distinct monocyte cytokine signature shared by clinically heterogeneous pediatric SLE patients. Journal of autoimmunity. July 2017; 81: 74-89. doi:https://doi.org/10.1016/j.jaut.2017.03.010 PubMed PMID: 28389038
Lai J, Nelson L, Balboni I, Lee T, Hsu J. Resilience and Transition Readiness in Pediatric SLE Patients [abstract]. Arthritis Rheumatol. 2017; 69 (suppl 10). https://acrabstracts.org/abstract/resilience-and-transition-readiness-in-pediatric-sle-patients/.