Topic List : Stem Cells
Elusive liver stem cell identified in mice by researchers
Researchers have found a previously unknown population of cells in mice that function as liver stem cells. The finding could aid drug testing and increase understanding of liver biology and disease.
Gene discoveries may lead to regeneration of cells needed for hearing
The researchers identified patterns of gene expression that may determine whether the ear’s inner pillar cells can give rise to new hair cells, which are key to hearing.
Ulcer-causing bacteria induces stomach stem cell growth in mice, researchers find
The findings could explain why H. pylori is a risk factor for gastric cancer, the researchers said.
Scientists find way to monitor progress of stem cells after transplantation into brain
The ability to detect successful engraftment, integration and function of human cells implanted into the brain of a living animal could potentially speed stem-cell therapies’ path to clinical use.
Cell type responsible for scarring, skin-cancer growth identified
A single cell type in the skin of mice is a major contributor to scarring after wound healing or radiation damage, and facilitates the growth of melanoma. Blocking the cell’s activity in humans may be possible with currently approved drugs.
5 Questions: Maria Grazia Roncarolo on advances in gene therapy
After leading successful clinical trials of gene therapy in Milan, Roncarolo hopes to build on that success at Stanford through collaboration with colleagues in the fields of genetics and stem cell science.
Researchers identify 'bridge' state necessary for cellular reprogramming
A new study shows that mature cells enter a unique transition state when being reprogrammed to iPS cells. Deconstructing the reprogramming process will help researchers better understand pluripotency.
New way to sort cells without limitations of traditional methods
The method is analogous to analyzing a smoothie to find what fruits went into making it, the researchers say.
Porteus receives $1M stem cell grant for ‘bubble boy disease’
The grant will allow the researcher to pursue a stem-cell-based gene therapy approach to correcting a form of severe combined immunodeficiency in humans.
Maria Grazia Roncarolo on fast-tracking stem cell and gene therapy to the clinic
Leading stem-cell expert and Stanford professor of pediatrics Maria Grazia Roncarolo, MD, will be leading a session on stem cell and gene therapy at Stanford’s inaugural Child X conference this spring.