Topic List : Stem Cells
Possible ‘bubble boy’ disease therapy
In preclinical trials, Stanford scientists and their collaborators harnessed the gene-editing system CRISPR-Cas9 to replace the mutated gene underpinning the devastating immune disease.
Gentler pre-transplant treatment with antibody
An antibody to a protein on blood-forming stem cells may allow bone marrow transplants without the need for chemotherapy and radiation, according to a Stanford study.
Transplants without tissue-matching?
Researchers’ experimental approach for preparing mice for blood stem cell transplantation may one day make it possible in humans to safely transplant organs or cells from any donor to any recipient.
What sea invertebrate reveals about us
A lowly sea creature may provide a way to understand our own blood-forming system, improve our immune function and find new immune-associated tools for biological discovery, Stanford researchers say.
Bee-made protein keeps stem cells primed
An active protein component of royal jelly helps honeybees create new queens. Stanford researchers have identified a similar protein in mammals, which keeps cultured embryonic stem cells pluripotent.
Adult stem cells channel early development
New research from Stanford shows that skeletal stem cells in mice assume a more primitive developmental state in response to extensive regeneration needs and environmental cues.
Human skeletal stem cell identified
Identification of the human skeletal stem cell by Stanford scientists could pave the way for regenerative treatments for bone fractures, arthritis and joint injuries.
New protein essential for making stem cells
The discovery by Stanford scientists drills a peephole into the black box of cellular reprogramming and may lead to new ways to generate induced pluripotent stem cells in the laboratory.
Study solves mystery of genetic mutation
Stanford researchers used genetic-editing tools and stem cell technology to uncover whether a genetic mutation linked to a heart rhythm disorder was benign or pathogenic.
Neurons quickly generated from blood
Fresh or frozen human blood samples can be directly transformed into patient-specific neurons to study disorders such as schizophrenia and autism, Stanford researchers find.