list : Genetics

  • How beneficial fats increase lifespan

    Fat from olive oil and nuts boosts the numbers of two key cellular structures and protects membranes from damage, lengthening the lives of laboratory worms, Stanford Medicine-led study finds.

  • How statins improve vascular health

    Statins designed to lower cholesterol have long been noted to work in mysterious ways to improve other aspects of cardiovascular health. A Stanford Medicine-led study uncovers how they do it.

  • DNA circles drive cancer development

    Tiny circles of DNA harbor cancer-associated oncogenes and immunomodulatory genes promoting cancer development. They arise during transformation from pre-cancer to cancer, say Stanford Medicine-led team.

  • Myc-caused sugar changes protect cancers

    A novel Stanford School of Medicine partnership uncovers a direct link between a cancer-associated gene, Myc, and sugar patterns on cancer cell surfaces that tell immune cells to stand down.

  • African-American Alzheimer’s risk factor

    A genetic risk factor found virtually exclusively among people of at least partial African ancestry substantially boosts the risk of incurring Alzheimer’s disease — but only sometimes.

  • Telomere length crucial in muscular dystrophy

    Telomeres shorten in heart muscle cells from people with Duchenne muscular dystrophy. A Stanford Medicine study finds blocking this process improves the health of these cells grown in a dish.

  • Blood drop yields lots of data

    Using a new technique called multi-omic microsampling, Stanford Medicine researchers can measure thousands of protein, fat and metabolic molecules from a single drop of blood.

  • $18 million for transplant and gene-editing research

    The California Institute for Regenerative Medicine has funded Stanford Medicine projects to improve kidney transplantation and advance treatment for a rare genetic disease in children.

  • Gel treatment heals blistering wounds

    Researchers find that a gel tested in patients with a life-threatening blistering skin disease helps wounds heal. The gel — the first topical gene therapy — awaits FDA approval.

  • Possible new way to kill cancer cells

    After finding long, repetitive sequences in the genomes of seven kinds of cancer, researchers at Stanford Medicine and their colleagues developed a molecule that curbed their production.