Topic List : Genetics
Puzzle of mutated gene in Parkinson’s
Why a defective gene is tied so strongly to Parkinson’s disease has baffled researchers. Now, a study led by Stanford scientists appears to have pieced together a major part of the puzzle.
DNA folding key to cell differentiation
In trying to decipher the “DNA origami” responsible for the generation of transplantable human skin, Stanford researchers have uncovered a master regulatory hierarchy controlling tissue differentiation.
Grant funds cell mapping of colon
Stanford scientists will map the cells of the human colon as part of a larger effort funded by the National Institutes of Health to create an atlas of all the cells in human tissues.
Genetics of rapid antler growth
Stanford scientists and their collaborators have identified two key genes responsible for the rapid growth of deer antlers. They hope their insights will open the door to new approaches for treating bone diseases and fractures.
Clue charting cancer gene regulation
Understanding when and where proteins bind to DNA may be the ticket to identifying cancer at the cellular level, according to researchers at Stanford.
Rearranging genome with CRISPR
Using a new variation of gene-editing technology CRISPR, Stanford scientists were able to change the spatial organization of DNA in cell nuclei and show how physical relocation altered cell function.
Undiagnosed patients get answers
A network of doctors that aims to diagnose mystery diseases has named 31 newly identified conditions and diagnosed more than 100 previously unsolved cases, according to a new study.
Mutations point to possible drug targets
Genetic data from nearly 300,000 patients has helped scientists find new potential drug targets for heart disease and diabetes, while shedding more light on the genetics of cholesterol, according to a new study.
Human ‘exposome’ revealed
Stanford scientists have measured the human “exposome,” or the particulates, chemicals and microbes that individually swaddle us all, in unprecedented detail.
‘Cascade’ testing identifies relatives at risk
An online effort coupled with lower costs significantly increased the proportion of cancer patients’ relatives who chose to undergo genetic testing for cancer-associated mutations in Stanford study.