Topic List : Genetics
Researchers find sleep gene linked to heart failure
Researchers have identified a previously unknown association between heart function and the narcolepsy-linked orexin receptor pathway, a finding that could provide a promising direction for treatment research.
Ancient viral molecules essential for human development
Genetic residue from ancient viral infections has been repurposed to play a vital role in acquiring pluripotency, the developmental state that allows a fertilized human egg to become all the cells in the body.
Stanford researchers identify potential security hole in genomic data-sharing network
Hackers with access to a person’s genome might find out if that genome is in an international network of disease databases.
Combination drug therapy shrinks pancreatic tumors in mice
When used together, two drugs that affect the structure and function of DNA blocked the growth of pancreatic tumor cells in mice. Researchers hope the drugs can soon be tested in humans with pancreatic cancer.
Researchers home in on biological cause of ALS
A mutation linked to amyotrophic lateral sclerosis interferes with the transport of proteins in and out of a cell’s nucleus. Targeting this pathway with drugs or therapies may one day help patients with neurodegenerative disease.
Unique genes in Khoe-San people may lower risk of some pregnancy hazards
An unusual mutation in an immune system gene switches a receptor from one target molecule to another. It’s the first known example of such a change, say Stanford researchers, and likely leads to safer pregnancies.
Researchers find mutations that contribute to rare blood cancer
Mutations in immune cells prevented their natural death in roughly half of the cell samples from patients with the incurable cancer, and suggest drug targets for the disease.
Researchers awarded $14 million for two precision health projects
Teri Klein and Russ Altman have received NIH funding to expand two ongoing projects that publish information about the connection between patients’ genetics and their responses to prescription drugs.
Women’s immune system genes operate differently from men’s
A new technology reveals that immune system genes switch on and off differently in women and men, and the source of that variation is not primarily in the DNA.
Kennewick Man closely related to Native Americans
The 8,500-year-old skeleton found in Washington, in 1996, has been the subject of a dispute. Now, genetic analyses of the ancient DNA suggest he is an ancestor of present-day Native Americans.