Topic List : Genetics
Immune cells speed aging brains’ demise
Stanford researchers have found intrusive immune cells in a place in the brains of humans and older mice where new nerve cells are born. The intruders appear to impair nerve cell generation.
Gene networks and heart failure
A Stanford-led research team has mapped out a network of gene activity before and after heart failure to better understand how heart health declines.
Increasing diversity in genome studies
Data scientist Genevieve Wojcik speaks about the lack of diversity in genomewide association studies, why it’s a problem and how increasing diversity in these studies can elevate the entire population.
Using RNA for rare-disease diagnosis
Geneticist Stephen Montgomery explains why the transcriptome, the collection of RNA molecules in a cell, is a crucial piece of deciphering the source of rare diseases.
Revealing health through big data
Years-long tracking of individuals’ biology helped define what it meant for them to be healthy and showed how changes from the norm could signal disease, a Stanford-led study reports.
Helping with NASA twins study
Stanford scientists and their collaborators found markers of immune-related stress and other molecular changes in the body of NASA astronaut Scott Kelly.
Possible ‘bubble boy’ disease therapy
In preclinical trials, Stanford scientists and their collaborators harnessed the gene-editing system CRISPR-Cas9 to replace the mutated gene underpinning the devastating immune disease.
Ovarian cancer mutations undertested
A large study of women with breast and ovarian cancer has revealed significant gaps between national guidelines for genetic testing and actual testing practices, according to researchers from Stanford and five other institutions.
Metabolic profiles of kids
Researchers from throughout Stanford Medicine are planning to study thousands of metabolites in babies, children and pregnant women to understand the origins of disease.
Puzzle of mutated gene in Parkinson’s
Why a defective gene is tied so strongly to Parkinson’s disease has baffled researchers. Now, a study led by Stanford scientists appears to have pieced together a major part of the puzzle.