Topic List : Cardiovascular Health
Possible drug target for cardiomyopathy
Stanford researchers have uncovered how a genetic mutation contributes to a heart disease known as familial dilated cardiomyopathy. Existing drugs correct the defect in heart cells grown in a petri dish, suggesting a new therapeutic target.
Stanford-led team awarded $10 million
Stanford scientists will direct a multidisciplinary, multi-institutional team focused on understanding in detail how tiny mutations in a protein, myosin, can cause the classic features of cardiomyopathy.
Gene networks and heart failure
A Stanford-led research team has mapped out a network of gene activity before and after heart failure to better understand how heart health declines.
E-cigarette flavorings harm blood vessel cells
E-cigarette flavorings damage human blood vessel cells grown in the lab even in the absence of nicotine, Stanford researchers and their colleagues found. Cinnamon and menthol flavors were particularly harmful.
Drug reduces kidney failure in diabetics
Canagliflozin, a drug approved to lower glucose levels in diabetic patients, can slow the progression of kidney disease, according to a study co-authored by a Stanford Medicine researcher.
Identifying familial hypercholesterolemia
Stanford scientists and their collaborators have devised an algorithm to predict the risk of a disease that, untreated, can lead to heart attack or stroke.
Mystery novel and dream spur key insight
On Dec. 14, 2014, after many months of not getting expected results, biochemist Jim Spudich got into bed, read a chunk of a novel, fell asleep and had a dream that would change the thinking in his field about what causes a common and often lethal heart defect.
Apple Heart Study demonstrates ability of wearable technology to detect atrial fibrillation
Stanford researchers presented preliminary findings from a virtual study that enrolled more than 400,000 participants.
Discovery could limit toxic effect of chemo
Stanford researchers have found a way to predict who will suffer heart problems from a common breast-cancer drug, as well as identified an FDA-approved medication that could mitigate those side effects.
Heart defects boost heart disease risk
Even a relatively simple heart defect makes a patient much more likely to develop cardiovascular disease as an adult, Stanford researchers say.