Topic List : Genetics
Helping women identify their risk for cancer
Researchers assigned levels of risk to 25 mutations associated with breast and ovarian cancer in a large, Stanford-led study. The results may be helpful in guiding treatment and screening recommendations.
New technology provides rare diagnosis
Stanford scientists have used a next-generation technology called long-read sequencing to diagnose a patient’s rare genetic condition that current technology failed to diagnose.
Disease genes not clustered
In a provocative new perspective piece, Stanford researchers say that disease genes are spread uniformly across the genome, not clustered in specific molecular pathways, as has been thought.
Ribosomes unexpectedly variable, powerful
Ribosomes, which make proteins, are startlingly variable in their composition and associations. This variability confers on them the ability to regulate genes, confounding previous ideas, Stanford researchers say.
Pilot grants for population health projects
The Stanford Center for Population Health Sciences has awarded 11 pilot grants to investigators with studies that seek to improve population and community health.
Too many unnecessary double mastectomies?
Women with breast cancer do not receive timely genetic testing or have adequate access to effective genetic counseling, which may compromise treatment decisions, according to research from Stanford and the University of Michigan.
Possible therapeutic approach for ALS
A set of experiments at Stanford reveals that suppressing a protein called ataxin 2 dramatically extends survival and improves motor function in a mouse model of ALS.
Master cell regulator blocks all but one outcome
A regulatory protein actively blocks the expression of non-neuronal genes in nerve cells, according to new Stanford research. The finding suggests there are many master regulators to help cell types maintain their identities.
Fat accumulation can lengthen life
Roundworms storing monounsaturated fats in their guts live longer, according to Stanford researchers. Their study links epigenetic regulation with fat metabolism, and may have implications for many species.
Many breast cancer patients ‘undertested’
Physicians often fail to recommend genetic testing to breast cancer patients at high risk for cancer-associated mutations. Improving access to genetic counseling about the testing process and results is a key priority.