Topic List : Stem Cells
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Molecule aids muscle regeneration in mice
Stanford researchers have found that a metabolite stimulates mouse muscle stem cells to proliferate after injury, and anti-inflammatory drugs, frequently taken after exercise, block its production and inhibit muscle repair.
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Protein helps speed wound healing
Pretreatment with a stem-cell-activating protein significantly enhances healing in mice, Stanford researchers say. The approach could eventually help people going into surgery or combat heal better from injuries they sustain.
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Patients blinded by treatment touted as ‘trial’
After three patients were blinded following a treatment marketed as a stem cell clinical trial, Stanford ophthalmologist Jeffrey Goldberg calls for increased patient education and regulation.
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Scientists awarded stem cell grants
The grants to Stanford researchers target stem cell-based therapies for autoimmune disorders, liver disease and cystic fibrosis.
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Rat-grown pancreases help save diabetic mice
Growing organs from one species in the body of another may one day relieve transplant shortages. Now researchers show that islets from rat-grown mouse pancreases can reverse disease when transplanted into diabetic mice.
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Fewer bone stem cells in diabetes impedes healing
Stanford researchers found that activating bone stem cells helps repair fractures in diabetic mice. Applying a protein to the fracture site increased the expression of key signaling proteins and enhanced healing in the animals.
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Samuel Strober awarded $6.6 million
The California Institute for Regenerative Medicine awarded Samuel Strober, MD, $6.6 million to study a “deceptively simple” way to help kidney transplant recipients tolerate their new organ.
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Stem cells police themselves to reduce scarring
Stem cells produce a decoy protein to attenuate growth signals. Artificially regulating this pathway might help keep muscles supple in muscular dystrophy or during normal aging, researchers hope.
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Canine cancer immunotherapy
The work extends research by Stanford scientists who found that blocking CD47 might be useful in treating human cancer.
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Paving the way for gene therapy
Using the CRISPR gene-editing technique in stem cells, Stanford researchers repaired the gene that causes sickle cell disease, and the mended stem cells were successfully transplanted into mice.
