Topic List : Stem Cells
Molecule aids muscle regeneration in mice
Stanford researchers have found that a metabolite stimulates mouse muscle stem cells to proliferate after injury, and anti-inflammatory drugs, frequently taken after exercise, block its production and inhibit muscle repair.
Protein helps speed wound healing
Pretreatment with a stem-cell-activating protein significantly enhances healing in mice, Stanford researchers say. The approach could eventually help people going into surgery or combat heal better from injuries they sustain.
Patients blinded by treatment touted as ‘trial’
After three patients were blinded following a treatment marketed as a stem cell clinical trial, Stanford ophthalmologist Jeffrey Goldberg calls for increased patient education and regulation.
Scientists awarded stem cell grants
The grants to Stanford researchers target stem cell-based therapies for autoimmune disorders, liver disease and cystic fibrosis.
Rat-grown pancreases help save diabetic mice
Growing organs from one species in the body of another may one day relieve transplant shortages. Now researchers show that islets from rat-grown mouse pancreases can reverse disease when transplanted into diabetic mice.
Fewer bone stem cells in diabetes impedes healing
Stanford researchers found that activating bone stem cells helps repair fractures in diabetic mice. Applying a protein to the fracture site increased the expression of key signaling proteins and enhanced healing in the animals.
Samuel Strober awarded $6.6 million
The California Institute for Regenerative Medicine awarded Samuel Strober, MD, $6.6 million to study a “deceptively simple” way to help kidney transplant recipients tolerate their new organ.
Stem cells police themselves to reduce scarring
Stem cells produce a decoy protein to attenuate growth signals. Artificially regulating this pathway might help keep muscles supple in muscular dystrophy or during normal aging, researchers hope.
Canine cancer immunotherapy
The work extends research by Stanford scientists who found that blocking CD47 might be useful in treating human cancer.
Paving the way for gene therapy
Using the CRISPR gene-editing technique in stem cells, Stanford researchers repaired the gene that causes sickle cell disease, and the mended stem cells were successfully transplanted into mice.