Topic List : Stem Cells
Protein clumps affect neural stem cells
Young, resting neural stem cells have large protein clumps often associated with neurodegeneration. As stem cells age, the aggregates inhibit their ability to make new neurons, Stanford researchers say.
Antibody treatment for ‘bubble boy’ disease
In a clinical trial, participants were given an antibody to CD117, a cell surface marker, in an effort to wipe out their defective blood stem cells without high-risk chemotherapy or radiation.
IPS cells slow tumor growth in mice
Priming the immune system with induced pluripotent stem cells prevented or slowed the development of cancer in mice, Stanford researchers found.
Faculty get funding from stem cell agency
Three Stanford faculty members were awarded $6 million to support research into a blistering skin disease, transplanted stem cells and novel ways to grow blood stem cells.
Stem cells for fat have circadian clock
New discoveries about the circadian-clock machinery in the precursors to fat cells may explain why shift workers are prone to metabolic diseases, such as diabetes, a Stanford study finds.
RNA labeling reveals stem cell secrets
The Stanford research suggests that any conclusions about stem cell function based on studies of stem cells in lab dishes may now need to be reconsidered in light of the fact that the cells’ biology changes during isolation.
Researchers discover lung stem cell in mice
Stanford scientists have found a cell that creates the two different compartments in the mouse lung. They hope their discovery could lead to better therapies for people with lung disease.
Animals don’t fully mimic human immune response
“Humanized” mice are used to study human immune responses, but they are inadequate for stem cell studies, say Stanford researchers. Optimized models are needed for clinical decision-making.
Molecule aids muscle regeneration in mice
Stanford researchers have found that a metabolite stimulates mouse muscle stem cells to proliferate after injury, and anti-inflammatory drugs, frequently taken after exercise, block its production and inhibit muscle repair.
Protein helps speed wound healing
Pretreatment with a stem-cell-activating protein significantly enhances healing in mice, Stanford researchers say. The approach could eventually help people going into surgery or combat heal better from injuries they sustain.