Topic List : Genetics
Exome sequencing program launched
The Clinical Genomics Program, which began as a pilot program a few years ago, offers whole-exome sequencing and analysis to patients with undiagnosed genetic diseases.
CRISPR helps reveal drug targets for ALS
Through genome editing, scientists at Stanford have pinpointed genes that reveal mechanistic details of ALS and may even protect against the degeneration of neurons.
Analysis reveals surprising DNA secrets
DNA twitches during transcription to bring distant regions in contact and enhance gene expression, according to Stanford researchers who devised a new way to label individual, nonrepetitive DNA sequences.
Weight flux alters molecular profile
Stanford scientists have found links between changes in a person’s weight and shifts in their microbiome, immune system and cardiovascular system.
Fixing hearts of infants with genetic defects
Infants with the genetic disorders trisomy 13 or 18 are more likely to survive if they undergo heart surgery, a study from researchers at Stanford and the University of Arkansas has found.
Genotype, gene expression linked in tissues
Understanding how a person’s DNA sequence affects gene expression in various tissues reveals the molecular mechanisms of disease. Stanford scientists involved in the National Institutes Health’s GTEx project have published some of their insights.
How parakeet feathers get their colors
Tracing the genetic process through which parakeets produce either yellow or blue feathers has given Stanford scientists insights that could help them uncover other biochemical pathways.
Speeding up research into rare disease
A Stanford “lending library” of biological samples and genomic information could accelerate diagnostic and therapeutic research for NGLY1 deficiency and related conditions.
Marsupial moms express placental genes in milk
Marsupials have short pregnancies. Their placentas mimic those of mice during early fetal development, while other key placental genes are expressed and secreted into milk for the offspring, Stanford researchers say.
Gamers to build on/off switch for CRISPR
Players will try to design a molecule that can turn CRISPR gene-editing on and off. Success could open the door to new research and therapies.