Brain tumor growth stopped
High-grade gliomas, a group of aggressive brain tumors, cease growing in mice if a signaling molecule called neuroligin-3 is absent or its activity is blocked with drugs, a Stanford team has shown.
Gamers to build on/off switch for CRISPR
Players will try to design a molecule that can turn CRISPR gene-editing on and off. Success could open the door to new research and therapies.
Animals don’t fully mimic human immune response
“Humanized” mice are used to study human immune responses, but they are inadequate for stem cell studies, say Stanford researchers. Optimized models are needed for clinical decision-making.
Center for Definitive and Curative Medicine created
The new Stanford Center for Definitive and Curative Medicine will work to turn discoveries into stem cell and gene therapies to aid the millions of people who have genetic diseases.
News staff wins top awards
Writers and editors in the medical school’s news office were recognized for the quality of the magazine and the news releases they produced in 2016.
Ribosomes unexpectedly variable, powerful
Ribosomes, which make proteins, are startlingly variable in their composition and associations. This variability confers on them the ability to regulate genes, confounding previous ideas, Stanford researchers say.
Molecule aids muscle regeneration in mice
Stanford researchers have found that a metabolite stimulates mouse muscle stem cells to proliferate after injury, and anti-inflammatory drugs, frequently taken after exercise, block its production and inhibit muscle repair.
Data sifting finds hidden gene partnerships
Targeting backup biological pathways often used by cancers can lead to more efficient drug development and less-toxic therapies. Stanford researchers have developed a new way to identify these pathways.
Cancer therapy may work in unexpected way
An antibody to the cell receptor PD-1 may launch a two-pronged assault on cancer by initiating attacks by both T cells and macrophages, a Stanford study has found.
Medical students present research projects
Juggling medical school and scientific research, Stanford students came together in a poster board competition to show the depth and breadth of their projects, from global health to stem cells.