D-limonene could offset dry mouth in cancer patients
A Stanford collaboration between clinical and basic science researchers has led to the identification of a compound that could improve the quality of life for head and neck cancer patients.
For ‘Project Lung,’ research gets personal
When James Spudich was diagnosed with lung cancer, researchers had a rare, and unexpected, opportunity to study healthy and diseased human tissue at an unprecedented level of detail.
$11.9 million for anti-leukemia trial
The California Institute for Regenerative Medicine awarded Stanford researcher Crystal Mackall a grant to study immune cells genetically modified to attack two proteins on leukemia and lymphoma cells.
Altered immune cells attack brain tumor
In mice, a fatal brainstem tumor was cleared by injecting it with engineered T cells that recognized the cancer and targeted it for destruction. The Stanford discovery is moving to human trials.
How liver regenerates itself
A subset of liver cells with high levels of telomerase renews the organ during normal cell turnover and after injury, according to Stanford researchers. The cells may also give rise to liver cancer.
Protein clumps affect neural stem cells
Young, resting neural stem cells have large protein clumps often associated with neurodegeneration. As stem cells age, the aggregates inhibit their ability to make new neurons, Stanford researchers say.
Misbehaving cells predict relapse in leukemia
Analyzing individual cancer cells has enabled Stanford researchers to identify the small population of cells that spur relapse in some children with leukemia.
Antibody treatment for ‘bubble boy’ disease
In a clinical trial, participants were given an antibody to CD117, a cell surface marker, in an effort to wipe out their defective blood stem cells without high-risk chemotherapy or radiation.
Seizure-regulating nerve cells identified
Stanford researchers have found that a small set of nerve cells in the brain regulates the debilitating seizures and cognitive deficits characteristic of the most common form of epilepsy in adults. This discovery could lead to new and better treatments.
IPS cells slow tumor growth in mice
Priming the immune system with induced pluripotent stem cells prevented or slowed the development of cancer in mice, Stanford researchers found.