Brain circuit drives sleep-wake cycle
Inhibiting the firing of nerve cells in a brain area long known to guide goal-directed behavior makes mice build nests and fall asleep, a new study shows. Stimulating the circuit roused the mice and kept them awake.
Study on treatment decisions seeks participants
The study is designed to collect neurophysiological and psychological information from women faced with a breast cancer diagnosis and many treatment decisions.
Retinoic acid deficiency linked to tumors
Levels of retinoic acid, a vitamin A metabolite, are low in mice and humans with colorectal cancer, according to new research. People with high levels of an enzyme that degrades retinoic acid have a poor prognosis.
How doctors answer e-cigarette questions
Researchers analyzed an online medical forum to better understand what patients want to know about e-cigarettes and how doctors respond to those questions.
Extra chemo ineffectual against rare bone cancer
Osteosarcoma patients with tumors that haven’t responded well to the standard chemotherapy regimen have unimproved outcomes and more side effects when given two additional drugs, a large international trial has found.
Mothers’ quandary on female circumcision
More Egyptian women are seeking the opinions of physicians on whether their daughters should undergo female genital cutting, which is illegal in the country, but they say doctors don’t advise against the procedure.
Approach for preventing obesity, eating disorders
New guidelines from the American Academy of Pediatrics tell pediatricians and parents to avoid focusing on teenagers’ weight and shape to prevent both obesity and eating disorders.
iPS cell-derived heart cells predict drug toxicity
Heart muscle cells made from induced pluripotent stem cells share gene expression patterns with native donor tissue, researchers discovered. These cells can be used to indicate people who should avoid certain medications that could damage their hearts.
Safer opioid analgesic designed
Morphine and similar drugs are the world’s most widely used painkillers. But they’re also dangerous and addictive. A new compound may be able to safely provide the same analgesia as morphine.
Computers trained in pathology
Automating the analysis of slides of lung cancer tissue samples increases the accuracy of tumor classification and patient prognoses, according to a new study.
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