Five projects receive Transdisciplinary Initiatives Program awards
The TIP program supports innovative, heterogeneous groups of scholars working to transform one another’s perspective on a child- or maternal-health problem.
The TIP program supports innovative, heterogeneous groups of scholars working to inform one another’s perspective on a child- or maternal-health problem. Teams comprise scientists from preclinical, clinical and basic science fields in the School of Medicine, as well as one or more faculty members from the School of Humanities and Sciences, School of Engineering, School of Business, School of Education, School of Law and School of Earth, Energy and Environmental Sciences.
Following are the titles of the projects and their transdisciplinary teams:
- “IPSC-derived cardiomyocytes to determine mechanisms by which beta-cardiac myosin mutations cause pediatric hypertrophic cardiomyopathy.” PI: Daniel Bernstein, MD, pediatrics. Co-PIs: Beth Pruitt, PhD, mechanical engineering; James Spudich, PhD, biochemistry; Alexander Dunn, PhD, chemical engineering.
- “Measuring children’s physical activity and sleep in the real world: Processing and analysis of high-dimensional accelerometry data using statistical learning techniques.” PI: Manisha Desai, PhD, medicine. Co-PIs: Thomas Robinson, MD, pediatrics; Clete Kushida, MD, PhD, psychiatry and behavioral sciences; Scott Delp, PhD, bioengineering, mechanical engineering; Ram Rajagopal, PhD, civil and environmental engineering; Dennis Wall, PhD, pediatrics.
- “Cerebellar circuitry in development, learning and clinical conditions.” PI: Heidi Feldman, MD, PhD, pediatrics. Co-PIs: Brian Wandell, PhD, psychology; Bruce McCandliss, PhD, education; Kristen Yeom, MD, radiology.
- “The NSD2 methyltransferase in pediatric ALL.” PI: Or Gozani, MD, PhD, biology. Co-PIs: Julien Sage, PhD, pediatrics, genetics; Justin Dubois, PhD, chemistry; Norman Lacayo, MD, pediatrics.
- “The role of ALDH2 genetic variation and aldehyde metabolism in hematopoietic stem cell biology and the pathogenesis of bone marrow failure.” PI: Kenneth Weinberg, MD, pediatrics. Co-PIs: Daria Mochly-Rosen, PhD, chemical and systems biology; Eric Kool, PhD, chemistry; Matthew Porteus, MD, PhD, pediatrics.
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