Program Information

Speakers

Felipe Albuquerque (Phoenix, USA)
Rustam Al-Shahi Salman (Edinburgh, UK)
Serge Bracard (Nancy, France)
Saruhan Cekirge (Ankara, Turkey)
Steve Chang (Stanford, USA)
Marie Faughnan (Toronto, Canada)
Ioannis Fouyas (Edinburgh, UK)
Haytham Hussein (Khartoum, Sudan)
Helen Kim (San Francisco, USA)
Douglas Kondziolka (New York, USA)
Michael Lawton (San Francisco, USA)
Dean Li (Salt Lake City, USA)
Michael Marks (Stanford, USA)
Michael McDermott (San Francisco, USA)
Phil Meyers (New York, USA)
J P Mohr (New York, USA)
Jacques Moret (Paris, France)
Michael Morgan (Sydney, Australia)
Darren Orbach (Boston, USA)
Jean Raymond (Montreal, Canada)
Howard A. Riina (New York, USA)
Georges Rodesch (Paris, France)
Laligham Sehkhar (Seattle, USA)
Gary Steinberg (Stanford, USA)
Hua Su (San Francisco, USA)
Joseph Sullivan (San Francisco, USA)
Ulrich Sure (Essen, Germany)
Miikka Vikkula (Brussels, Belgium)
Reinhard Wurm (Berlin, Germany)
Hong-Qi Zhang (Beijing, China)
Yuanli Zhao (Beijing, China)

Scientific Committee

Felipe Albuquerque
Rustam Al-Shahi Salman
Sepideh Amin-Hanjani
Serge Bracard
Jan Burkhardt
Saruhan Cekirge
Steven D. Chang
Omar Choudhri
Ling Feng
Ioannis Fouyas
Peter Gooderham
Raphael Guzman
Michael Kelly
Douglas Kondziolka
Michael Lawton
Michael Marks
J P Mohr
Jacques Moret
Michael Morgan
Georges Rodesch
Gary Steinberg
Philipp Taussky

Organizing Committee

Omar Choudhri
Ann Crevelt
Faith Harding
Michael Lawton
Marco Lee
Gary Steinberg
Cindy Samos
Elizabeth Hoyte

Special Guest Speakers:

Dr Pascal Lee is Chairman of the Mars Institute, Senior Planetary Scientist at the SETI Institute, and Director of the NASA Haughton-Mars Project at NASA Ames Research Center in Moffett Field, California. He has worked extensively in the Arctic and Antarctica viewed as planetary “analogs” and is internationally recognized for his efforts to advance the human exploration of Mars. He was scientist-pilot in the first field test of NASA’s new Space Exploration Vehicle, a concept spacecraft currently under development for future human exploration of the Moon, Near-Earth Asteroids, and Mars. He also recently led the Northwest Passage Drive Expedition, a record-setting Mars simulation rover trek on sea-ice along the fabled Northwest Passage in the Arctic.


Katherine and Ben Perreth mother-son inspirational duo, present at medical and educational conferences. Their talk, “20 Years Living With A Veritable Mess: Spetzler-Martin Grade 4 Hemorrhage, Craniotomy & Proton Beams” will give a unique perspective from a parent and patient’s point of view.  Katherine is also an award-winning author and her book,  Making Lemonade With Ben: The Audacity to Cope, includes 3 essays by Ben and will be available at the book table - just look for the flying lemons. Ben juggles one-handed everywhere he goes in order to accomplish his life goal: "Make humanity smile."

Program

Monday, 24 October PM

9.00 am - onward Registration

1.45 pm   Opening Ceremony

2.00-4.00 pm   Session I Basic Sciences/Pathogenesis

Moderator: Michael Lawton

2.00-2.20  Exploiting machine learning and artificial intelligence to the study of vascular anomalies and other genetic diseases. Dean Li (Salt Lake City, USA)

2.20-2.40  Etiological insights from genetics of AVM.  Miikka Vikkula (Brussels, Belgium)

2.40-3.00   Identifying therapeutic targets using brain AVM animal models. Hua Su (San Francisco, USA)

3.00-3.20  Genome wide association studies in sporadic brain AVM.  Helen Kim (San Francisco, USA)

3.20-3.30  Thalidomide and Lenalidomide treatment stabilizes the vascular wall and reduces microhemorrhage in mouse brain AVM. Wan Zhu (San Francisco, USA)

3.30-3.40  Hedgehog signaling in human brain AVMs. Roberto Pola (Boston, USA)

3.40-3.50  Alk1 Deficiency in Bone Marrow-Derived Endothelial Cells Leads to AVMs. Quiang Li (San Francisco, USA)

3.50-4.00  Nitric oxide synthase inhibition attenuates the formation of Notch-mediated brain AVM. Rong Wang (San Francisco, USA)

4.00-4.30 pm  Break/Exhibit

4.30-6.00pm  Session II Clinical practice-World view

Moderator: Robert Dodd

4.30-4.50  Contrasts on AVM management in China with the world. Yuanli Zhao (Beijing, China)

4.50-5.10   A global view of the outcome for people with untreated brain AVMs. Rustam Al-Shahi Salman (Edinburgh, UK)

5.10-5.20   Treatment of AVM in Sudan Haytham Husein (Khartoum, Sudan)

5.20-5.55   Consult the experts: Multi-disciplinary panel discussion of COMMON cases. Serge Bracard, Saruhan Cekirge, J P Mohr, Laligham Sehkhar, Michael Marks, Gary Steinberg

5.55-6.00   Day 1 Closing Remarks

6.00-8.00 pm   Welcome Reception (Taste of Napa)

8.00-9.00 pm   Fireside talk: Passage to Mars- Pascal Lee


Tuesday, 25 October AM

7.30-8.30 am  Breakfast

8.30-10.15 am  Session III Pediatric Brain AVM

Moderator: Raphael Guzman

8.30-8.50   Unruptured brain AVM in the pediatric population. Darren Orbach (Boston, USA)

8.50-9.10   Management of seizures associated with AVM in the pediatric population. Joseph Sullivan (San Francisco, USA)

9.10-9.30  AVM associated syndromes. Marie Faughnan (Toronto, Canada)

9.30-9.40  AVMs at a rare anatomic and developmental interface.  Omar Choudhri (San Francisco, USA)

9.40-9.50  Multimodality Management of Spetzler-Martin Grade 3 Brain Arteriovenous Malformations with Subgroup Analysis. Isaac J. Abecassis (Seattle, USA)

9.50-10.15  20 Years Living With A Veritable Mess: Spetzler-Martin Grade 4 Hemorrhage, Craniotomy & Proton Beams (parent & patient perspective). Katherine and Ben Perreth (Madison, USA)

10.15-10.45 am  Break/Exhibit

10.45-12.30 pm  Session IV Brain AVM Surgery

Moderator: David Langer

10.45-11.05  How and why my practice changed after ARUBA- a neurosurgeon’s perspective. Ioannis Fouyas (Edinburgh, UK)

11.05-11.25  Surgical treatment of AVM after radiosurgery. Gary Steinberg (Stanford, USA)

11.25-11.45  Role of embolization before surgery. Michael Morgan (Sydney, Australia)

11.45-12.05  Surgical treatment of brain AVM.   Michael Lawton (San Francisco, USA)

12.05-12.15  Surgical management of low-grade unruptured brain arteriovenous malformations in non-neurologically impaired patients. Eduardo Martinez-del-Campo (Phoenix, USA)

12.15-12.30   How I would do it differently? Laligham Sehkhar USA (Seattle, USA)

12.30-1.30 pm  Lunch/Exhibit


Tuesday, 25 October PM

1.30-3.30 pm   Session V Brain AVM Endovascular

Moderator: Philip Taussky

1.30-1.50  Indications of embolization prior to AVM surgery. Phil Meyers. (Columbia, USA).

1.50-2.10  How do associated aneurysms change AVM management? Ulrich Sure (Essen, Germany)

2.10-2.30   Is there a role of pre-radiosurgical embolization of AVMs? Michael Marks (Stanford, USA)

2.30-2.45  How I would do it differently? Serge Bracard (Nancy, France)

2.45-3.30   Debate. Motion: The first line approach with the goal of curative treatment of grade 1-2 AVM should now be endovascular.   Saruhan Cekirge, Jacque Moret, Felipe Albuquerque, Ulrich Sure,  Philip Myers, Michael Lawton

3.30-4.00 pm  Break/Exhibit

4.00-6.00 pm  Session VI Brain AVM Radiosurgery

Moderator: Steven Chang

4.00-4.20  Hypofractionated or staged compartment radiosurgery treatment in large AVMs? Reinhard Wurm (Berlin, Germany)        

4.20-4.40  Volume staged radiosurgery for large AVMs. Michael McDermott (San Francisco, USA)

4.40-4.50  Arterial-Spin Labeling for the Non-Invasive Follow-Up of Cerebral AVMs Following Stereotactic Radiosurgery Treatment. Neil Thakur (Stanford, USA)

4.50-5.00  Higher Flow Is Present In Unruptured Arteriovenous Malformations With Silent Microhemorrhage. Xiaolin Chen (San Francisco, USA)

5.00-5.15   How I would do it differently. Douglas Kondziolka (New York, USA)

5.15-6.00  Debate. Motion: Radiosurgery rather than surgery is the treatment of choice in grade 1-2 AVMs.   Douglas Kondziolka, Reinhard Wurm, Michael McDermott. Darren Orbach, Howard Riina, Steven D. Chang

7.00 pm Banquet dinner (ticketed event)


Wednesday, 26 October AM

7.30-8.30 am  Breakfast

8.30-10.15 am  Session VII Spinal AVM

Moderator: Michael Marks

8.30-8.50 Natural history of spinal AVM.  Georges Rodesch (Paris, France)

8.50-9.10  Endovascular treatment of spinal AVM. Felipe Albuquerque (Phoenix, USA)

9.10-9.30  Surgical treatment of spinal AVM. Zhang Hongqi (Beijing, China)

9.30-9.50   Radiosurgical treatment of spinal AVM.  Steven D. Chang (Stanford, USA)

9.50-10.00  CyberKnife radiosurgery for spinal cord AVMs. Eric S. Sussman (Stanford, USA)

10.00-10.10  The Study on the Treatment of Brain AVMs (TOBAS): Feasibility of a randomized controlled care trial and Registry. Elsa Magro (Brest, France)

10.10-10.25  How I would do it differently. Howard A. Riina (New York, USA)

10.25-10.30am Announcements

10.30-11.00am Break/Exhibit

11.00-1.00pm  Session VIII Future Directions

Moderator: Gary Steinberg

11.00-11.20 Future Directions for the Management of Brain AVMs. Michael Lawton (San Francisco, USA)

11.20-11.40  Transvenous or transarterial approach to AVMs? Jacques Moret (Paris, France)

11.40-12.00  Trials intergrated to care: The Treatment of Brain AVM study (TOBAS) Jean Raymond (Montreal, Canada)

12.00-12.45   Debate. Motion: More randomized trials involving people with brain AVMs are needed. J P Mohr, Rustam Al-Shahi Salman, Laligham Sehkhar, Jean Raymond, Michael Morgan, Ioannis Fouyas

12.35-12.55pm  Open Forum: Have your say

12.55-1.00 pm  Closing ceremony and remarks

1.00 pm Lunch (Box Lunch to go)