The Stanford Neuro-Oncology Program Adult Clinical Trials

Newly Diagnosed Glioma

A Follow-Up Study to Add Whole Brain Radiotherapy (WBRT) to Standard Temozolomide Chemo-Radiotherapy in Newly Diagnosed Glioblastoma (GBM) Treated with 4 Weeks of Continuous Infusion Plerixafor
PI: Lawrence Recht
Co-PI: Reena Thomas
Clinicaltrials.gov#: NCT03746080

Recurrent High Grade Glioma

ONC201 in Adults With Recurrent H3 K27M-mutant Glioma
PI: Reena Thomas
ClinicalTrials.gov#: NCT03295396

TTAC-0001 Phase II Trial With Recurrent Glioblastoma Progressed on Bevacizumab
PI: Seema Nagpal
ClinicalTrials.gov#: NCT03856099

CNS Diagnostic Imaging

Phase I/II, Open-Label Study Evaluating the Efficacy and Pharmacokinetics of Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Neoplasms during Neurosurgical Procedure
PI: Gordon Li
Clinicaltrials.gov#: NCT03510208

A Phase I Study of [18F]DASA-23 as a PET Tracer for Evaluating Pyruvate Kinase M2 (PKM2) Expression in Healthy Volunteers and in Patients with Intracranial Tumors
PI: Sanjiv Gambhir
Clinicaltrials.gov#: NCT03539731

A Pilot Study to Assess Lactate and Bicarbonate Detection Within Malignant Brain Tumors Using [1-13C]-Pyruvate DNP Magnetic Resonance Spectroscopy (MRS)
PI: Lawrence Recht
Clinicaltrials.gov#: NCT03565367