Small Molecule Design Laboratory

Our laboratory focuses on the design and discovery of synthetic and natural product inspired small molecules which can be used as probes to understand biological phenomena, including protein-protein interactions and modulation of signal transduction pathways. We employ the tools of synthetic & medicinal chemistry, molecular modeling and chemical biology for translational research in drug discovery, development, imaging and radiation. Our current projects include design of new scaffolds/molecules as chemical tools to study various solid tumors; Alzheimer and markers for screening of hypoxic metabolically active cells.