Bioengineering/Radiology 222A Fall 2013
Multi-modality Molecular Imaging in Living Subjects
Course Syllabus
CLASSES: Mondays & Fridays 9-10:50 AM LK 308
Week | Monday | Instructor | Friday | Instructor |
1 | 9/23 | Introduction to Molecular Imaging C. Contag |
9/27 | Radionuclide Physics C. LevinLecture notes
Emission Tomography: The Fundamentals of PET and SPECT. Eds. Wernick and Aarsvold. Elsevier Academic Press, 2004. Chapter 4 |
2 | 9/30 | Tomographic Image Reconstruction C. LevinLecture notes
Emission Tomography: The Fundamentals of PET and SPECT. Eds. Wernick and Aarsvold. Elsevier Academic Press, 2004. Chapters 20, 21 Alessio A. PET Image Reconstruction. Nuclear Medicine, 2nd Ed. |
10/4 | Positron Emission Tomography (PET) C. LevinLecture notes
Molecular Imaging: Principles and Practice Chapter 7 Molecular Imaging with Reporter Genes Chapter 7 Emission Tomography: The Fundamentals of PET and SPECT. Eds. Wernick and Aarsvold. Elsevier Academic Press, 2004. Chapter 10 |
3 | 10/7 CCSR 4107 |
Single Photon Emission Computed Tomography (SPECT) C. LevinLecture notes
Molecular Imaging: Principles and Practice Chapter 7 Molecular Imaging with Reporter Genes Chapter 7 Emission Tomography: The Fundamentals of PET and SPECT. Eds. Wernick and Aarsvold. Elsevier Academic Press, 2004. Chapters 7, 8 |
10/11 | Multi-modality Molecular Imaging Systems (PET/CT and PET/MRI) C. LevinLecture notes (75MB)
Molecular Imaging: Principles and Practice Chapter 7 Emission Tomography: The Fundamentals of PET and SPECT. Eds. Wernick and Aarsvold. Elsevier Academic Press, 2004. Chapter 11 |
4 | 10/14 | Tissue optics E. GravesLecture notes
Rice BW, et al. In vivo imaging of light-emitting probes. J Biomedical Optics 2001;6(4):432-40. Ntziachristos V, et al. Looking and listening to light: the evolution of whole-body photonic imaging. Nat Biotech 2005;23(3):313-320. Troy T, et al. Quantitative Comparison of the Sensitivity of Detection of Fluorescent and Bioluminescent Reporters in Animal Models. Mol Imaging 2004;3(1):9-23. Weissleder R, et al. Shedding light onto live molecular targets. Nat Med 2003;9(1):123-8. |
10/18 | Fluorescence Imaging E. GravesLecture notes
Graves EE, et al. A submillimeter resolution fluorescence molecular imaging system for small animal imaging. Med Physics 2003;30(5):901-11. Ntziachristos V, et al. Experimental three-dimensional fluorescence reconstruction of diffuse media by use of a normalized Born approximation. Opt Lett 2001;26(12):893-5. Patterson MS, et al. Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties. Applied Opt 1989;28(12):2331-36. |
5 | 10/21 LK130 |
Bioluminescence Imaging E. Graves |
10/25 | Raman Scatter Imaging C. Zavaleta |
6 | 10/28 | MID-TERM EXAM |
11/1 | Ultrasound Imaging K. Butts Pauly |
7 | 11/4 CCSR 4107 |
Nuclear Magnetic Resonance (NMR) Physics M. MoseleyLecture notes
Molecular Imaging: Principles and Practice Chapter 3, 26, 51, 53-54, 69 |
11/8 | Magnetic Resonance Imaging (MRI) M. MoseleyLecture notes
Molecular Imaging: Principles and Practice Chapter 3, 26, 51, 53-54, 69 |
8 | 11/11 | Photoacoustic Tomography A. de la Zerda |
11/15 LK208 |
Technology for Cellular and Molecular MRI B. Rutt |
9 | 11/18 | Early disease detection and monitoring with ultrasound molecular imaging J. WillmannLecture notes
Deshpande N. Molecular ultrasound imaging: current status and future directions. Clin Radiol. 2010;65(7):567-81. Pysz MA. Targeted contrast-enhanced ultrasound: an emerging technology in abdominal and pelvic imaging. Gastroent. 2011;140(3):785-90. Kiessling F. Ultrasound microbubbles for molecular diagnosis, therapy, and theranostics. JNM. 2012;53(3):345-8. |
11/22 | Molecular Imaging of Cardiac Stem Cell Therapy P. Nguyen |
Thanksgiving recess (11/25-11/29). No class. | ||||
10 | 12/2 | Molecular Imaging of Cancer Z. ChengLecture notes
Frangioni JV. New technologies for human cancer imagingc. J Clin Oncol. 2008;26(24):4012-21. Gambhir SS. Molecular imaging of cancer with positron emission tomography. Nat Rev Cancer. 2002;2(9):683-93. Vallabhajosula S. A broad overview of positron emission tomography radiopharmaceuticals and clinical applications: what is new?. Semin Nucl Med. 2011;41(4):246-64. |
12/6 LK208 |
Molecular Imaging of the Brain M. James |
FINAL EXAM Wednesday, December 11, 2013 at 8:30-11:30am CCSR 4205 |
||||
11 | TBD | Tours of Small Animal Imaging Facility and Molecular Imaging Clinic C. Levin |