Bioengineering/Radiology 222A Fall 2011
Multi-modality Molecular Imaging in Living Subjects
Course Syllabus
CLASSES: Mondays & Fridays 9-10:50 AM, LKSC-LK306
Week | Monday | Instructor | Friday | Instructor |
1 | 9/26 | Primer on Cellular and Molecular Biology for Imaging C. Contag Lecture notes
Molecular Imaging: Principles and Practice Chapters 1, 38 Molecular Imaging with Reporter Genes Chapters 3, 10 Joseph Sambrook, David Russell. Molecular Cloning: A Laboratory Manual. Vol 1. 3rd Ed. CSHL Press. |
9/30 | Primer on Biochemistry for Molecular Imaging J. Rao Lecture notes
Molecular Imaging: Principles and Practice Chapter 19 Razgulin A, Maa N and Rao JH. Strategies for in vivo imaging of enzyme activity: an overview and recent advances. Chem Soc Rev 2011;40:41864216. |
2 | 10/3 | Radionuclides Physics C. Levin Lecture notes
Emission Tomography: The Fundamentals of PET and SPECT. Eds. Wernick and Aarsvold. Elsevier Academic Press, 2004. Chapter 4 |
10/7 | Tomographic Image Reconstruction C. Levin Lecture notes
Emission Tomography: The Fundamentals of PET and SPECT. Eds. Wernick and Aarsvold. Elsevier Academic Press, 2004. Chapters 20, 21 Alessio A. PET Image Reconstruction. Nuclear Medicine, 2nd Ed. |
3 | 10/10 | Positron Emission Tomography (PET) C. Levin Lecture notes
Molecular Imaging: Principles and Practice Chapter 7 Molecular Imaging with Reporter Genes Chapter 7 Emission Tomography: The Fundamentals of PET and SPECT. Eds. Wernick and Aarsvold. Elsevier Academic Press, 2004. Chapter 10 |
10/14 | Single Photon Emission Computed Tomography (SPECT) C. Levin Lecture notes
Molecular Imaging: Principles and Practice Chapter 7 Molecular Imaging with Reporter Genes Chapter 7 Emission Tomography: The Fundamentals of PET and SPECT. Eds. Wernick and Aarsvold. Elsevier Academic Press, 2004. Chapters 7, 8 |
4 | 10/17 | Multi-modality Molecular Imaging Systems (PET/CT and PET/MRI) C. Levin Lecture notes
Molecular Imaging: Principles and Practice Chapter 7 Emission Tomography: The Fundamentals of PET and SPECT. Eds. Wernick and Aarsvold. Elsevier Academic Press, 2004. Chapter 11 |
10/21 | Tissue optics E. Graves Lecture notes
Rice BW, et al. In vivo imaging of light-emitting probes. J Biomedical Optics 2001;6(4):432-40. Ntziachristos V, et al. Looking and listening to light: the evolution of whole-body photonic imaging. Nat Biotech 2005;23(3):313-320. Troy T, et al. Quantitative Comparison of the Sensitivity of Detection of Fluorescent and Bioluminescent Reporters in Animal Models. Mol Imaging 2004;3(1):9-23. Weissleder R, et al. Shedding light onto live molecular targets. Nat Med 2003;9(1):123-8. |
5 | 10/24 | Fluorescence Imaging E. Graves Lecture notes
Patterson MS, et al. Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties. Applied Opt 1989;28(12):2331-36. Graves EE, et al. A submillimeter resolution fluorescence molecular imaging system for small animal imaging. Med Physics 2003;30(5):901-11. Ntziachristos V, et al. Experimental three-dimensional fluorescence reconstruction of diffuse media by use of a normalized Born approximation. Opt Lett 2001;26(12):893-5. |
10/28 | Bioluminescence Imaging E. Graves |
6 | 10/31 | Ultrasound Imaging K. Butts Pauly |
11/4 | Nuclear Magnetic Resonance (NMR) Physics M. Moseley Lecture notes
Molecular Imaging: Principles and Practice Chapter 3, 26, 51, 53-54, 69 |
7 | 11/7 | Magnetic Resonance Imaging (MRI) M. Moseley Lecture notes
Molecular Imaging: Principles and Practice Chapter 3, 26, 51, 53-54, 69 |
11/11 | MRI Pulse Sequences and Image Reconstruction M. Moseley Lecture notes
Molecular Imaging: Principles and Practice Chapter 3, 26, 51, 53-54, 69 |
8 | 11/14 | Ultrasonic Molecular Imaging: Principles and Applications J. Willmann Lecture notes
Deshpande N, et al. Molecular Ultrasound Assessment of Tumor Angiogenesis. Angiogenesis. 2010;13(2):175188. Willmann J, et al. Targeted Contrast-Enhanced Ultrasound Imaging of Tumor Angiogenesis with Contrast Microbubbles Conjugated to Integrin-Binding Knottin Peptides. JNM 2010;51(3):433-440. |
11/18 | Cardiovascular Molecular Imaging with MRI M. McConnell |
Thanksgiving recess (11/21-11/25). No class. | ||||
9 | 11/28 | Molecular Image Guided Radiation Therapy L. Xing |
12/2 | Technology for cellular and molecular MRI B. Rutt |
10 | 12/5 | Imaging Pain S. Biswal |
12/9 | Molecular Imaging of Cancer using PET Z. Cheng |
FINAL RESEARCH PROPOSALS Due: December 9, 2011 at 2pm |
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11 | TBD | Tours of Small Animal Imaging Facility, Molecular Imaging Clinic, and Radiation Oncology Clinic C. Levin, L. Xing |