Bioengineering/Radiology 222 Course Syllabus

Classes: Monday & Friday, 9:00 - 10:50 AM Beckman Center B-230

09/26 Introduction to Molecular Imaging [ Part 1 | Part 2 ] Dr. Levin
09/30 Optics (physics): 3D fluorescence imaging [ Download PDF - 12.5MBB ]pdf icon Dr. Graves
10/03 Optics (physics): Tissue optics [ Download PDF - 47.7MB ]pdf icon

Biomedical Photonics Handbook [ Download PDF - 7MB ]pdf icon
  • Tromberg B, et al. Non-Invasive In Vivo Characterization of Breast Tumors Using Photon Migration Spectroscopy. Neoplasia 2000; 2(1-2):26-40.
    [ Download PDF - 2.1MB ]
Dr. Contag
10/07 Chemistry of Fluorescence [ Download PDF - 9.2MB ]pdf icon Dr. Rao
10/10 Optics Application: Intervital Optical Neuroimaging [ Download PDF - 19.4MB ]pdf icon Dr. Schnitzer
10/14 Optics Application: Optical Reporter Genes [ Download PDF - 26.5MB ]pdf icon
  • Tsien RY. The Green Fluorescent Protein. Annu. Rev. Biochem. 1998; 67:509-44.
    [ Download PDF - 545KB ]pdf icon
  • Contag C, Bachmann MH. Advances in In Vivo Bioluminescence Imaging of Gene Expression. Annu. Rev. Biomed. Eng. 2002; 4:235-60.
    [ Download PDF - 353KB ]pdf icon
Dr. Contag
10/17 SPECT Physics [ Download PDF - 12.7MB ]pdf icon Principles of Computerized Tomographic Imaging. Kak, Slaney, IEEE Press, 1988.

Physics in Nuclear Medicine. Cherry, Sorenson, Phelps, 3rd Edition. Saunders, 2003.

Dr. Levin
10/21 PET Physics [ Download PDF - 9.9MB ]pdf icon Principles of Computerized Tomographic Imaging. Kak, Slaney, IEEE Press, 1988.

Physics in Nuclear Medicine. Cherry, Sorenson, Phelps, 3rd Edition. Saunders, 2003.

Dr. Levin
10/24 Radiochemistry [ Download PDF - 4.2MB ]pdf icon Dr. Chen
10/28 PET Imaging of Integrin Expression [ Download PDF - 10MB ]pdf icon Dr. Chen
10/31 Imaging of Apoptosis [ Download PDF - 7.2MB ]
  1. Belhocine TZ, Tait JF, Vanderheyden JL, Li C, Blankenberg FG. Nuclear medicine in the era of genomics and proteomics: lessons from annexin V. J Proteome Res. 2004 May-Jun;3(3):345-9.
    [ Download PDF - 156KB ]pdf icon
  2. Blankenberg FG. Recent advances in the imaging of programmed cell death. Curr Pharm Des. 2004;10(13):1457-67. Review.
    [ Download PDF - 296KB ] pdf icon
  3. Blankenberg F, Mari C, Strauss HW. Imaging cell death in vivo. Q J Nucl Med. 2003 Dec;47(4):337-48. Review.
    [ Download PDF - 272KB ]pdf icon
  4. Lahorte CM, Vanderheyden JL, Steinmetz N, Van de Wiele C, Dierckx RA, Slegers G. Apoptosis-detecting radioligands: current state of the art and future perspectives. Eur J Nucl Med Mol Imaging. 2004 Jun;31(6):887-919.
    [ Download PDF - 428KB ]pdf icon
  5. Kolodgie FD, Petrov A, Virmani R, Narula N, Verjans JW, Weber DK, Hartung D, Steinmetz N, Vanderheyden JL, Vannan MA, Gold HK, Reutelingsperger CP, Hofstra L, Narula J. Targeting of apoptotic macrophages and experimental atheroma with radiolabeled annexin V: a technique with potential for noninvasive imaging of vulnerable plaque. Circulation. 2003 Dec 23;108(25):3134-9.
    [ Download PDF - 384KB ]pdf icon
  6. Blankenberg FG, Strauss HW. Nuclear medicine applications in molecular imaging. J Magn Reson Imaging. 2002 Oct;16(4):352-61. Review.
    [ Download PDF - 288KB ]pdf icon
Dr. Blakenberg
11/04 MR Basic Principles [ Download PDF - 1.8MB ]pdf icon Dr. McConnell
11/07 Cardiovascular MRI/Targeted MRI Contrast Agents [ Download PDF - 6.1MB ]pdf icon Dr. McConnell
November 9, 2005 - Midterm Exam
3:30-5:00 PM
Place: Lucas Magnetic Imaging Center, Room P083
The exam will be open book and cover the first 11 lectures.
11/11 Neuroimaging by MR [ Download PDF - 15.6MB ]pdf icon Dr. Moseley
11/14 MR for Molecular Imaging [ Download PDF - 7.1MB ]pdf icon Dr. Moseley
11/18 Vascular development and Vascular Imaging [ Download PDF - 7.6 MB ]pdf icon Dr. Guccione
11/28 Multi-modality Assays for Small Animal Imaging [ Part A 3.4MB, Part B 6.2MB ]pdf icon
  • Massoud T, Gambhir SS. Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes & Development 2003 17:545-580. [ Download PDF - 29.7MB ]
Dr. Wu
12/02 Applications of Molecular Imaging in Radiation Therapy (1) [ Download PDF - 10.6MB ]pdf icon Dr. Graves
12/05 Applications of Molecular Imaging in Radiation Therapy (2) [ Download PDF - 1.2MB ]pdf icon Dr. Xing
12/09 Applications of Molecular Imaging in Humans [ Download PDF - 26.5MB ]pdf icon Dr. Gambhir
TBD Tour of Small Animal Imaging Facility Dr. Doyle
December 16, 2005 - Final Exam