Bioengineering/Radiology 222
Course Syllabus

CLASSES: 9:00 - 10:50 AM Beckman Center B-200B

09/27 Introduction to Molecular Imaging [ Part 1 | Part 2 ] Dr. Gambhir
Dr. Levin
09/29 Optics (physics): Tissue Optics
[ Download PDF - 3 MB ]pdf icon

Biomedical Photonics Handbook
[ Download PDF - 7 MB ]pdf icon Tromberg B, et al. Non-Invasive In Vivo Characterization of Breast Tumors Using Photon Migration Spectroscopy. Neoplasia 2000; 2(1-2):26-40.
[ Download PDF - 2.1 MB ]pdf icon		 Dr. Contag
10/04 Optics (physics): 3D Fluorescence Imaging
[ Download PDF - 10.9 MB ]pdf icon		 Dr. Graves
10/06 MR Basic Principles
[ Download PDF - 1.8 MB ]pdf icon		 Dr. McConnell
10/11 SPECT/PET Physics
[ Download PDF - 21.6 MB ]pdf icon Physics in Nuclear Medicine. Cherry, Sorenson, Phelps, 3rd Edition. Saunders, 2003.

Principles of Computerized Tomographic Imaging. Kak, Slaney, IEEE Press, 1988.

 Dr. Levin
10/13 Chemistry of Fluorescence
[ Download PDF - 9.2 MB ]pdf icon		 Dr. Rao
10/18 Optics Application: Intervital Optical Neuroimaging
[ Download PDF - 19.4 MB ]pdf icon		 Dr. Schnitzer
10/20 Optics Application: Optical Reporter Genes Tsien RY. The Green Fluorescent Protein. Annu. Rev. Biochem. 1998; 67:509-44.
[ Download PDF - 545 KB ]pdf icon

Contag C, Bachmann MH. Advances in In Vivo Bioluminescence Imaging of Gene Expression. Annu. Rev. Biomed. Eng. 2002; 4:235-60.
[ Download PDF - 353 KB ]pdf icon

 Dr. Contag
10/25 Digital Autoradiography Dr. Gambhir
10/27 Cardiovascular MRI/Targeted MRI Contrast Agents
[ Download PDF - 6.1 MB ]pdf icon		 Dr. McConnell
11/01 Vascular Imaging/Angiogenesis/Targeted Vascular Imaging
[ Download PDF - 2.3 MB ]pdf icon		 Dr. Guccione
11/03 Radiochemistry
[ Download PDF - 10.8 MB ]pdf icon		 Dr. Chen
11/08 Tumor Angiogenesis Imaging
[ Download PDF - 30.6 MB ]pdf icon		 Dr. Chen
11/10 Neuroimaging by MR
[ Download PDF - 15.6 MB ]pdf icon		 Dr. Moseley
11/15 MR for Molecular Imaging
[ Download PDF - 7.1 MB ]pdf icon		 Dr. Moseley
11/17 Imaging of Apoptosis
[ Download PDF - 5.8 MB ]pdf icon
  1. Belhocine TZ, Tait JF, Vanderheyden JL, Li C, Blankenberg FG. Nuclear medicine in the era of genomics and proteomics: lessons from annexin V. J Proteome Res. 2004 May-Jun;3(3):345-9.
    [ Download PDF - 156 KB ]pdf icon
  2. Blankenberg FG. Recent advances in the imaging of programmed cell death. Curr Pharm Des. 2004;10(13):1457-67. Review.
    [ Download PDF - 296 KB ] pdf icon
  3. Blankenberg F, Mari C, Strauss HW. Imaging cell death in vivo. Q J Nucl Med. 2003 Dec;47(4):337-48. Review.
    [ Download PDF - 272 KB ] pdf icon
  4. Lahorte CM, Vanderheyden JL, Steinmetz N, Van de Wiele C, Dierckx RA, Slegers G. Apoptosis-detecting radioligands: current state of the art and future perspectives. Eur J Nucl Med Mol Imaging. 2004 Jun;31(6):887-919.
    [ Download PDF - 428 KB ] pdf icon
  5. Kolodgie FD, Petrov A, Virmani R, Narula N, Verjans JW, Weber DK, Hartung D, Steinmetz N, Vanderheyden JL, Vannan MA, Gold HK, Reutelingsperger CP, Hofstra L, Narula J. Targeting of apoptotic macrophages and experimental atheroma with radiolabeled annexin V: a technique with potential for noninvasive imaging of vulnerable plaque. Circulation. 2003 Dec 23;108(25):3134-9.
    [ Download PDF - 384 KB ] pdf icon
  6. Blankenberg FG, Strauss HW. Nuclear medicine applications in molecular imaging. J Magn Reson Imaging. 2002 Oct;16(4):352-61. Review.
    [ Download PDF - 288 KB ] pdf icon
 Dr. Blankenberg
11/22 Multi-modality Assays for Small Animal Imaging [ Download PDF's - Part A 29.7 MB, Part B 28.2 MB ]pdf icon Massoud T, Gambhir SS. Molecular imaging in living subjects: seeing fundamental biological processes in a new light. Genes & Development 2003 17:545-580. pdf icon Dr. Gambhir
11/24 Human Molecular Imaging Applications
[ Download PDF - 26.5 MB ]pdf icon Gambhir SS. Molecular Imaging of Cancer With Positron Emission Tomography. Nature Cancer 2002 2:683-693. pdf icon		 Dr. Gambhir
11/29 Applications of Molecular Imaging in Radiation Therapy (1) Dr. Xing
1201 Applications of Molecular Imaging in Radiation Therapy (2) Dr. Graves
Final Exam