Steady-State Diffusion Imaging

Diffusion-weighted steady-state free precession (DW-SSFP) has long been recognized to offer potential benefits over conventional spin-echo methods. This family of pulse sequences is highly efficient and compatible with three-dimensional acquisitions, which could enable high-resolution, low-distortion images. However, the same properties that lead to its efficiency make steady-state imaging highly susceptible to motion and create a complicated signal with dependence on T1, T2 and flip angle. Recent developments in gradient hardware, motion-mitigation techniques and signal analysis offer potential solutions to these problems, reviving interest in DW-SSFP.

Diffusion Tractography of Post-mortem Human Brains: A Comparison of Spin Echo and Steady-State Free Precession Techniques

Miller KL, McNab JA, Jbabdi S, Douaud G

NeuroImage, 2012, 59(3):2284-2297.

 

Steady-state Diffusion-weighted imaging: Theory, Acquisition and Analysis

McNab JA, Miller KL

NMR in Biomedicine, 2010, 23(7):781-93.

 

3D Steady-State Diffusion-Weighted Imaging with Trajectory Using Radially Batched Internal Navigator Echoes (TURBINE)

McNab JA, Gallichan D, Miller KL

Magnetic Resonance in Medicine, 2010, 63(1):235-42.

 

High Resolution Diffusion Weighted Imaging in Fixed Human Brain Using Diffusion Weighted Steady State Free Precession

McNab JA, Jbabdi S, Deoni SCL, Douaud G, Behrens TEJ, Miller KL

NeuroImage, 2009, 46(3):775-785.

 

Sensitivity of Diffusion-weighted Steady-state Free Precession to Diffusion Anisotropy

McNab JA, Miller KL

Magnetic Resonance in Medicine, 2008, 60(2):405-413.