Executive Committee


Sanjiv Sam Gambhir, MD, PhD

Chair, Department of Radiology

Virginia & D.K. Ludwig Professor for the Clinical Investigation in Cancer Research

Current Interests

My laboratory is developing imaging assays to monitor fundamental cellular/molecular events in living subjects including patients. Technologies such as micro positron emission tomography (microPET), bioluminescence optical imaging, fluorescence optical imaging, micro computerized axial tomography (microCAT), ultrasound, photoacoustics, Raman imaging are all being actively investigated in small animal models. Our goals are to marry fundamental advances in molecular/cell biology with those in biomedical imaging to advance the field of molecular imaging. We have a particular interest in cancer biology and gene therapy. Research in early cancer detection and pharmacological therapy assessment is also being performed. Assays to interrogate cells for mRNA levels, cell surface antigens, intracellular proteins and protein-protein interactions are under active development. We are also extending many of these approaches for human clinical applications using optical and PET-CT technologies.

Gary H. Glover, PhD

Professor, Department of Radiology

Co-Director, Radiological Sciences Laboratory

Director, Lucas Service Center

Current Interests

My research interests encompass the physics and mathematics of imaging with Magnetic Resonance. Presently my research is directed in part towards exploration of rapid MRI scanning methods using spiral and other non-Cartesian k-space trajectories for dynamic imaging of function. Using spiral techniques, we have developed MRI pulse sequences and processing methods for mapping cortical brain function by imaging the metabolic response to various stimuli, with applications in the basic neurosciences as well as for clinical applications. These methods develop differential image contrast from hemodynamically driven increases in oxygen content in the vascular bed of activated cortex, using pulse sequences sensitive to the paramagnetic behavior of deoxyhemoglobin or to the blood flow changes. Other applications include imaging of contrast uptake in the breast.


Office 650.723.7577

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Garry Gold, MD

Professor, Department of Radiology

Current Interests

My primary focus is application of new MR imaging technology to musculoskeletal problems. Current projects include: Rapid MRI for Osteoarthritis, Weight-bearing cartilage imaging with MRI, and MRI-based models of muscle. We are studing the application of new MR imaging techniques such as rapid imaging, real-time imaging, and short echo time imaging to learn more about biomechanics and pathology of bones and joints.


Kim Butts Pauly, PhD

Professor, Department of Radiology

Co-Director, Radiological Sciences Laboratory

Current Interests

We are investigating the use of focused ultrasound for neuromodulation of the brain for direct stimulation and inhibition of the brain for preclinical mapping of brain function, reduction of epileptic seizures, and for general study of the brain. We are using focused ultrasound to open the blood brain barrier in order to enhance drug delivery to cancers of the brain. We are also using focused ultrasound to thermally ablate tissue for movement disorders such as essential tremor, as well as for cancers in the body. In addition to the basic science study of neuromodulation and cancer treatment, we are also engineering key MRI methods that enable monitoring these interventions, include MR thermometry, MR-acoustic radiation force imaging, and phase aberration correction using a combined approach of simulation and ultrashort echo time MRI imaging of bone.