Welcome to the Longo Lab


Our
Research
Team

Is focused on the discovery of cellular signaling mechanisms that serve as a basis for the development of therapeutic approaches for:

  • Alzheimer's Disease
  • Huntington's Disease
  • Parkinson's Disease
  • Charcot Marie Tooth  Disease

In the lab's Neurotrophin Program, we pioneered the development of small molecule ligands targeted to neurotrophin receptors to promote novel signaling mechanisms. Small molecule-induced modulation of these mechanisms demonstrates therapeutic efficacy in models of:

  • Alzheimer's Disease
  • Huntington's Disease
  • Parkinson's Disease
  • Charcot Marie Tooth  Disease
  • Stroke
  • Multiple Sclerosis
  • Spinal Cord injury
  • Rett Syndrome
  • Down's Syndrome

These novel compounds also stimulate stem cells to promote the formation of new neurons. One of our compounds is currently under development for anticipated human trials.

Neurology & Neurological Sciences

The Longo Lab is part of the Department of Neurology & Neurological Sciences

Contact Us

  • Research Assistant and Lab Manager
    Nadia Belichenko
    Stanford University
    (650) 736-0770
    nbeliche@stanford.edu