Chamberland S, Yang HH, Pan M, Evans SW, Chavarha M, Yang Y, Salesse C, Wu H, Wu JC, Clandinin TR, Toth K, Lin MZ, St-Pierre F. Fast two-photon imaging of subcellular voltage dynamics in neuronal tissue with genetically encoded indicators. eLife, in review. 

Zhou XX, Fan LZ, Li P, Shen K, Lin MZ. 2017. Optical control of cell signaling by single-chain photoswitchable kinases. Science 355 (6327): 836-842. PDF

Bajar BT†, Lam AJ†, Badiee RK, Oh YH, Chu J, Zhou XX, Kim N, Kim BB, Chung M, Yablonovitch A, Cruz BF, Kulalert K, Tao JJ, Meyer T, Su XD, Lin MZ. 2016. Fluorescent indicators for simultaneous reporting of all four cell cycle phases. Nature Methods Published online 31 October 2016 (†equal contribution). PDF

Laviv T†, Kim BB†, Chu J, Lam AJ, Lin MZ††, Yasuda Ryohei††. 2016. Simultaneous dual-color fluorescence lifetime imaging with novel red-shifted fluorescent proteins. Nature Methods Published online 31 October 2016 (†equal contribution, ††co-correspondence). PDF Video

Lin MZ, Schnitzer MJ. 2016. Genetically encoded indicators of neuronal activity. Nature Neuroscience 19: 1142-1153. Link

Ng HL, Lin MZ. 2016. Structure-guided wavelength tuning in far-red fluorescenct proteins. Curr Opin Structural Biol 39: 124-133. PDF

Chu J, Oh Y, Sens A, Ataie N, Dana H, Macklin JJ, Laviv T, Welf ES, Dean KM, Zhang F, Kim BB, Tang CT, Hu M, Baird MA, Davidson MV, Kay MA, Fiolka R, Yasuda R, Kim DS, Ng HL, Lin MZ. 2016. A bright cyan-excitable orange fluorescent protein facilitates dual-emission microscopy and enhances bioluminescence imaging in vivo. Nature Biotech. 34: 760-767. PDF

Yang HH†, St-Pierre F†, Sun X, Ding X, Lin MZ, Clandinin TR. 2016. Subcellular imaging of voltage and calcium signals reveals neural processing in vivo. Cell 166: 1-13 (†equal contribution). 

Bajar BT, Wang ES, Lam AJ, Kim BB, Jacobs CL, Howe ES, Davidson MW, Lin MZ, Chu J. 2016. Improving brightness and photostability of green and red fluorescencet proteins for live cell imaging and FRET reporting. Scientific Reports 6: 20889. Link

Chung HK, Jocobs CL, Huo Y, Yang J, Krumm SA, Plemper RK, Tsien RY, Lin MZ. 2015. Tunable and reversible drug control of protein production via a self-excising degron. Nature Chem Biol 11: 713-720. Link

Zhou XX, Pan M, Lin MZ. 2015. Investigating neuronal function with optically controllable proteins. Front Mol Neurosci 8: 37. Link

St-Pierre F, Charvarha M. 2015. Designs and sensing mechanims of genetically encoded fluorescent voltage indicators. Curr Opin Chem Biol 27: 31-38. Link

Fan LZ, Lin MZ. 2015. Optical control of biological processes by light-switchable proteins. Wiley Interdiscip Rev Dev Biol 4: 545-554. Link

St-Pierre F, Marshall JD, Yang Y, Gong Y, Schnitzer MJ, Lin MZ. 2014 .High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensors. Nature Neuroscience 17: 884-889 (Most read Nature Neuroscience article in May 2014). Link

Chu J, Haynes RD, Corbel SY, Li P, Gonzalez-Gonzalez E, Burg JS, Ataie NJ, Lam AJ, Cranfill PJ, Baird MA, Davidson MW, Ng HL, Garcia KC, Contag CH, Shen K, Blau HM, Lin MZ. 2014. Non-invasive intravital imaging of cellular differentiation with a bright red-excitable fluorescent protein. Nature Methods 11: 572-578. Link

Kim B, Lin MZ. 2013. Optical control of biological processes via protein engineering. Biochem Soc Trans 41:1183-1188. Link

Zhou XX, Lin MZ. 2013. Photoswitchable fluorescent proteins: ten years of colorful chemistry and exciting applications. Curr Opin Chem Biol 17: 682-690. Link

Zhou XX, Chung HK, Lam AJ, Lin MZ. 2012. Optical control of protein activity by fluorescent protein domains. Science 9: 810-814. Pubmed Free full text Free PDF

Butko MT, Yang J, Geng Y, Kim HJ, Jeon NL, Shu X, Mackey MR, Ellisman MH, Tsien RY, Lin MZ. 2012. Live fluorescent TimeSTAMP tags reveal stimulus-induced local expression of new postsynaptic proteins. Nature Neuroscience 15: 1742-1751. Link

Lam, AJ, St-Pierre F, Gong Y, Marshall J, Cranfill PJ, Baird MA, McKeown MR, Wiedenmann J, Davidson MW, Schnitzer M, Tsien RY, Lin MZ. 2012. Improving FRET dynamic range with bright green and red fluorescent proteins. Nature Methods 9: 1005-1012. Link

Lin MZ, Tsien RY. 2010. TimeSTAMP tagging of newly synthesized proteins. Current Protocols in Protein Science Chapter 26: Unit 26.5.

De Jaco A, Lin MZ, Dubi N, Miller M, Comoletti D, Ellisman M, Timmers M, Tsien RY, Taylor P 2010.. Disease-associated mutations in the a/b-hydrolase fold affect processing and trafficking of Neuroligin-3. Journal of Biological Chemistry 285: 28674. Link

Lin MZ, McKeown MR, Aguilera T, Shaner NC, Campbell RE, Adams SR, Tsien RY. Fluorescent proteins with excitation in the optical window for intravital imaging in mammals. Chemistry and Biology 16: 1169-1179. Link

Shu X, Royant A, Lin MZ, Aguilera T, Levram-Ellisman V, Steinbach PA, Tsien RY. 2009. Mammalian expression of infrared fluorescent proteins engineered from a bacterial phytochrome. Science 324: 804-807. PDF

Lin JY, Lin MZ, Steinbach P, Tsien RY. 2009. Characterization of engineered channelrhodopsin variants with improved properties and kinetics. Biophysical Journal 96: 1803-1814. PDF

Lin MZ, Wang L. 2008. Selective labeling of proteins with chemical probes in living cells. Physiology 23: 131-141. PDF

Lin MZ, Glenn JS, Tsien RY. 2008. A drug-controllable tag for specific labeling of newly synthesized proteins in cells and whole animals. PNAS 105: 7744-7749. (Cover article, featured in “A time stamp for proteins” Nature Methods 5: 662-663. PDF

Shaner NC, Lin MZ, McKeown MR, Steinbach PA, Hazelwood KL, Davidson MW, Tsien RY. 2008. Identification of bright monomeric orange and red fluorescent proteins with superior photostability. Nature Methods 5: 545-551. PDF

Sahin M*, Greer PL*, Lin MZ*, Poucher H, O’Connell S, Schmidt S, Wright TM, Shamah SM, Eberhart J, Cowan CW, Hu L, Goldberg JL, Debant A, Corfas G, Krull CE, Greenberg ME. 2005. Eph-dependent tyrosine phosphorylation of ephexin1 modulates growth cone collapse. Neuron 46: 191-204. *Equal authorship. PDF [stored on site] (Featured in “New Exchanges in Eph-Dependent Growth Cone Dynamics” Neuron 46: 141. PDF [stored on site])

Cowan CW, Shao YR, Sahin M, Shamah SM, Lin MZ, Greer PL, Gao S, Griffith EC, Brugge JS, Greenberg ME. 2005. Vav family GEFs link activated Ephs to endocytosis and axon guidance. Neuron 46: 205-217. PDF [stored on site]

Lin MZ, Teitell M, Schiller G. 2005. The evolution of antibodies into versatile tumor targeting agents. Clinical Cancer Research 11: 129-138. PDF [stored on site]

Datta SR, Ranger AM, Lin MZ, Sturgill JF, Ma YC, Cowan CW, Dikkes P, Korsmeyer SJ, Greenberg ME. 2002. Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis. Developmental Cell 3: 631-643. PDF [stored on site]

Watson FL, Heerssen HM, Bhattacharyya A, Klesse L, Lin MZ, Segal RA. 2001. Neurotrophins use the Erk5 pathway to mediate a retrograde survival response. Nature Neuroscience 4: 981-988. PDF [stored on site]

Shamah SM*, Lin MZ*, Goldberg JL, Estrach S, Sahin M, Hu L, Bazalakova M, Neve RL, Corfas G, Debant A, Greenberg ME. 2001. EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin. Cell 105:233-244. *Equal authorship. PDF [stored on site] (Featured in “Signaling Downstream of Eph Receptors and Ephrin Ligands” Cell 105: 701. PDF [stored on site])

Sun Y, Nadal-Vicens M, Misono S, Lin MZ, Zubiaga A, Hua X, Fan G, Greenberg ME. 2001. Neurogenin promotes neurogenesis and inhibits glial differentiation by independent mechanisms. Cell 104: 365-376. PDF [stored on site]

Dalva MB, Takasu MA, Lin MZ, Shamah SM, Hu L, Gale NW, Greenberg ME. 2000. EphB receptors interact with NMDA receptors and regulate excitatory synapse formation. Cell 103:945-56 PDF [stored on site]

Lin MZ, Greenberg ME. 2000. Orchestral maneuvers in the axon: Trio and the control of axon guidance. Cell 101:239-42. PDF [stored on site]