Our study on abnormalities in activity-induced synaptic protein expression in a Fragile X model is out in PNAS: https://www.pnas.org/content/116/24/12007. We found that new copies of PSD95 fail to be induced by local neurotrophin stimulation in neurons lacking the Fragile X mental retardation protein, but the effect can be rescued with kinase inhibitors. Congrats to Ying, Yang, Lin, and Dongyun, whose dedication, creativity, and teamwork made these discoveries possible.
Our paper describing Rewiring of Aberrant Signaling to Effector Release (RASER), a synthetic pathway for specifically detecting and ablating cancer cells, is out in Science: https://science.sciencemag.org/content/364/6439/eaat6982. Congrats to Kay, Xinzhi, Bryce, Veronica, and Yunwen!
Our paper reporting a bioluminescent indicator for non-invasive calcium imaging in mice is out in Nature Chemical Biology: https://rdcu.be/bue7I. Congrats to Younghee!
Michael Westberg from University of Aarhus has joined the lab as a Novo Nordisk Chem-H postdoctoral fellow. Welcome, Michael!
Guofeng Zhang from Zhongshan School of Medicine of Sun Yat‐sen Unive has joined the lab as a visiting scholar. Welcome, Guofeng!
Yichi Su from UC Berkeley has joined the lab as a postdoc. Welcome, Yichi!
Our paper reporting a method to preserve protein function using antiviral drugs is out in Nature Methods:https://rdcu.be/2j6N. Congrats to Conor!
Dongyun Jiang from Penn State Unviersity has joined the lab as a postdoc. Welcome, Dongyun!
Kay (Hokyung) Chung, Conor Jacobs, and Mariya Chavarha are receiving their PhD diplomas. Congratulations, Mariya and Kay.
Our paper "Excitation wavelength optimization improves photostability of ASAP-family GEVIs", a collaboration with Guoqiang Bi’s lab, has been published in Molecular Cell:https://www.ncbi.nlm.nih.gov/pubmed/29866136/
We welcome Xinzhi Zou (BioE) to the Lin lab as our newest graduate student.
We welcome Connor Ludwig (BioE) to the lab as rotation student and Melat Birbo as undergraduate student.
Congratulations to Kay on her successful thesis defense!
We welcome Mengli to the lab as joint PhD student, Xinzhi Zou (BioE) and Chung-ha Oh Davis (neuroscience) to the lab as rotation students.
Our paper on photoswitchable single-chain Cas9 proteins is published https://www.ncbi.nlm.nih.gov/pubmed/28938067 Congratulations to Xin, Xinzhi and Kay!
Our collaborative work on improving CRY2 for optobiochemical control is published in Nature Communications: https://www.ncbi.nlm.nih.gov/pubmed/28916751 Congratulations to Namdoo and Michael!
Congratulations to Conor on his successful thesis defense!
Kay receives a Hans Neurath Outstanding Promise Travel Award from the 2017 Protein Society Annual Meeting in Montreal, Canada and presents posters at the symposium.
Julianne Kim, Muziyue Wu, Tyler Dao, and Scott Meyer join the lab as summer students. Welcome, Julianne, Muziyue, Tyler, and Soctt!
Ryan graduates from Stanford and accepts the school of medicine admission from UCSF! Congratulations, Ryan!
Vandon Duong joins the lab as a research assistant. Welcome, Vandon!
Xin is giving a talk in the Brain Rejuvenation Project Mini-Symposium
Dongqing, David and Cory join the Lin lab. Welcome, Dongqing, David and Cory!
Xin gives a talk at Winter Q-Bio
Congrats to Xin on the publication of her Science paper "Optical control of cell signaling by single-chain photoswitchable kinases"
Congrats to Xin on her successful thesis defense and for accepting a position in the Wells lab at UCSF
Mariya gives a talk at the 2016 Society for Neuroscience in San Diego, California.
Congrats to Bryce on the publication of his Nature Methods paper "Fluorescent indicators for simultaneous reporting of all four cell cycle phases"
Congrats to Ben on the publication of his Nature Methods paper "Simultaneous dual-color fluorescence lifetime imaging with novel red-shifted fluorophores”
Stephen and Yunhee join the Lin lab. Welcome, Stephen and Yunhee!
Ying has been awarded The NARSAD Young Investigator Grant to study protein synthesis deficits in Fragile X syndrome.
Michael published a review in Nature Neuroscience on "Genetically encoded indicators of neuronal activity."
Michael published a review in Current Opinion in Structural Biology on "Structure-guided wavelength tuning in far-red fluorescenct proteins.”
Our collaboration work with Clandinin lab on ASAP2f is published in Cell! Congrats,Francois! Link
Xinzhi and Hokyung join the Lin lab for the summer. Welcome, Xinzhi and Hokyung!
Jun, Younghee and Ben's paper on cyOFP is now online at Nature Biotechnology! Congrats, everyone! Link
Deze and Stephan join the lab for the spring quarter rotation. Wecome!
Our high school student Julia receives and accepts the addmission from Massachusetts Institute of Technology (MIT)! Congratulations, Julia!
Lin joins our lab as a postdoctoral fellow. Welcome, Lin!
Yang joins the Interdisciplinary Research Center on Biology and Chemistry in Shanghai, China. Congrats on the new position, Yang!
Patrick, Heejo and James join the lab for the winter quarter rotation. Welcome everyone!
Xin gives a talk at the 2015 New Advances in Optical Imaging of Live cells and Organisms at Cold Spring Harbor Laboratory in Suzhou, China.
Baby girl Audrey Lijie Lin was born on Nov 8! Congratulations, Michael and Sherry!
Conor, Ying, Yang present posters at the 2015 Society for Neuroscience (SFN) at Chicago, IL.
Xin presents poster at the 2015 Engineering the Brain Conference at Chicago, IL.
First-year Bioengineering graduate student Hannah Kempton joins lab for a fall-quarter rotation. Welcome, Hannah!
Our former lab member Yunwen re-joins the lab as our lab manager. Wecome back, Yunwen!
LP joins the lab as a postdoctoral fellow. Welcome, LP!
Our paper on SMASh: Small-molecule assisted protein shut-off is published https://www.ncbi.nlm.nih.gov/pubmed/26214256 Congratulations to Kay, Conor and Yunwen!
Lin lab members had a great time at Barcelona for the 29th annual symposium of the Protein Society! Francois gave a talk, and Kay, Xin, Conor, Francois presented posters at the symposium. Xin's poster won a poster award! Congrats, Xin!
Francois receives the job offer from Baylor college of medicine and Rice University! He will become a joint faculty member at Baylor and Rice! Big congrats, Francois!
Michael gives a talk at the CLEO conference in San Jose.
Amy formally graduates from her PhD study! Congratulations, Amy!
Michael gives a talk at OSA Optics in Life Sciences held in Vancouver.
Jun will become a faculty member at Shenzhen Institutes of Advanced Technology in China! Congratulations, Jun!
Michael gives a talk at the Keystone Optogenetics conference in Denver.
Michael gives a talk at SPIE in San Francisco.
Michael gives a talk at the international symposium on multi-dimensional fluorescence live imaging of cellular functions and molecular activities in Kyoto.
Our first graduate student, Amy Lam,passes her PhD thesis defense on December 2! Excellent job, Amy!
Stanford News reports our new grant on developing tools for recording brain activity! Link
Michael gives talks at Labeling and Nanoscopy Conference in Heidelberg and Fluorescent Protein and Biological Sensors Conference at Janelia Farm.
Xin presents a poster at Fluorescent Protein and Biological Sensors Conference at Janelia Farm.
Kay presents a poster at the EMBL chemical biology conference in Heidelberg, Germany.
Michael gives talks at the Canadian Society of Chemistry Annual Meeting in Vancouver and the iCEMS International Symposium on Light Control in Cell Biology in Kyoto.
Michael gives a talk at the MIT McGovern Institute Symposium on Disruptive Innovations in Neuroscience in Cambridge, MA.
Francois and Ying's Nature Neuroscience paper "High-fidelity optical reporting of neuronal electrical activity with an ultrafast fluorescent voltage sensor" is published online. Congrats, Francois and Ying!
Michael gives a talk at the Gordon Research Conference on Photosensory Receptors and Signal Transduction in Barga, Italy.
Jun's Nature Methods paper "Non-invasive intravital imaging of cellular differentiation with a bright red-excitable fluorescent protein" is published online! Congrats, Jun!
Linlin, Jun, and Francois present posters in the 2014 Biophysical Society conference in San Francisco.
Michael gives talks at ION on 2/6 and KIST on 2/11.
Michael is selected as one of 12 recipients of this year's NIH Pioneer Award, a $2.5 million award for high-risk high-impact research. Thanks, NIH!
Maya Nagawa and Shireen Rudina join the lab as new BioE PhD rotation students. Welcome, Maya and Shireen!
Michael presents at the Campus Alberta Neuroscience Symposium on Optogenetics.
Michael gives a talk and Jun got a poster award at the 2013 Cold Spring Harbor (CSH) Asia Conference in Suzhou, China! Congrats, Jun!
Benjamin Kim joins the lab as a new BioE master's student. Welcome, Ben!
Chao Liu joins the lab as a summer rotation student! Welcome, Chao!
Xiaozhe Ding joins the lab as a 2013 summer undergraduate visiting scholar! Welcome, Xiaozhe!
Xin is awarded the Howard Hughes Medical Institute International Student Fellowship! Congrats, Xin!
Aditya Nandy joins the lab as a high school student participating in the Stanford Institutes of Medical Research (SIMR) Program! Welcome, Aditya!
Mariya joins the lab for a summer-quarter rotation. Welcome, Mariya!
Jessica rejoins the lab for the summer! Welcome back, Jessica!
Michael gives talks at Peking University, Tsinghua University, the Beijing Institute of Biophysics, Seoul National University, and and Korean Institute of Advanced Studies.
Amy, Kay and Xin receive the Protein Science Young Investigator Travel Award for the 2013 Annual Meeting!
Jihye Seong joins the lab as a postdoctoral fellow. Welcome, Jihye!
Welcome Ying's baby Anthony Ouyang to the family!! Tony was born on 04/24/2013.
Emily wins the 2013 Amgen Bay Area BioGENEius Challenge! Congrats, Emily!
Amanda Miguel joins the lab for a spring-quarter rotation. Welcome, Amanda!
Welcome Hyokeun's second baby to the family!
Michael is selected to give a talk in the NEW and NOTABLE session at the 2013 Biophysical Society Annual Meeting!
Xin receives a travel award from the 2013 Biophysical Society Annual Meeting!
Michael receives a Rising Star award at the Annual Meeting of the Biomedical Engineering Society's Cellular and Molecular Bioengineering Subgroup. Thanks, BMES!
The lab has received a Damon Runyon-Rachleff Innovation Grant to fund research in creating cancer-detecting switches for biological therapies. Thanks, Damon Runyon Foundation!
Xin, Kay, and Amy's paper ,"Optical control of protein activity by fluorescent protein domains" , has been accepted to Science. Congrats, Xin, Kay, and Amy!
Margaret and Yang's paper, "Fluorescent and photo-oxidizing TimeSTAMP tags track protein fates in light and electron microscopy", done in collaboration with Roger Tsien's lab, has been accepted to Nature Neuroscience. Congrats, Margaret and Yang!
Margaret Butko has joined the lab as a postdoctoral fellow, and Emily Wang has joined as a high school intern. Welcome, Margaret and Emily!
Amy and Francois' paper on "Improving FRET dynamic range with bright green and red fluorescent proteins" has been accepted to Nature Methods. Congrats, Amy and Francois!
Linlin Fan joins the lab as a undergraduate visiting researcher from Peking University.
Jacqueline Tao joins the lab (and William Chen rejoins) as Bioengineering REU students.
Justin Zhang joins the lab as a high school intern. Welcome, Justin!
The Lin Lab has moved into a larger space in CCSR 2100!
Bioengineering undergraduate William Chen joins the lab.
Amy Lam presents a poster on improving FRET dynamic range at the Stanford Bio-X Interdisciplinary Initiatives Symposium.
Lin Lab alum Nikhil Desai has been named an Intel Talent Search Finalist. Congrats, Nikhil!
The Lin and Schnitzer labs have been awarded a Stanford Bio-X NeuroVentures Grant to develop new methods for imaging brain activity. Thanks, Bio-X!
Postdoctoral scholar Dr. Younghee Oh joins the lab.
Michael Lin gives a talk at the Molecular and Cellular Cognition Society meeting in Washington DC on new TimeSTAMP tags for visualizing newly synthesized proteins in neurons.
The Lin Lab welcomes three new members to the lab: Hokyung Chung, visiting student researcher; Dr. Ying Yang, postdoctoral scholar; and Xin Zhou, returning now as a graduate student!
NIH/NINDS has awarded the lab a R01 grant to study the regulation of protein synthesis during synaptic plasticity. Thank you, NINDS!
NIH/NIGMS has awarded the lab a EUREKA R01 grant to develop methods for drug control of protein synthesis. Thank you, NIGMS!
The Lin Lab has been awarded a NSF grant to develop genetically encoded voltage sensors. Thank you, NSF!
The Lin Lab goes on their second annual Hill Hike at Portola Redwoods State Park, followed by dinner at the Alpine Inn. Everybody survives both.
The Lin Lab welcomes Chi Zhang as an undergraduate visiting researcher and Nikhil Desai as a Stanford Institutes of Medicine high school summer student.
Michael Lin has been named a Rita Allen Foundation Scholar. The Rita Allen Foundation awards $500,000 to young scientists in the fields of neuroscience, oncology, and immunology, with the mission of investigating in transformative ideas in their earliest stages to promote breakthrough solutions to significant problems. Thank you, Rita Allen Foundation!
The Lin Lab has been awarded a grant from the DoD to investigate mental retardation mechanisms.
Postdoctoral scholar Dr. Francois St-Pierre joins the lab.
The Alliance for Cancer Gene Therapy has awarded Michael Lin a young investigator award to develop protein-based switches for improving safety and specificity of genetically engineered cancer treatments. Thank you, ACGT!
The Lin Lab has been awarded a Stanford Bio-X Interdisciplinary Initiatives Award to improve voltage sensors, in collaboration with the Schnitzer lab. Thanks, Bio-X!
Michael Lin gave a talk on "Expanding the range of genetically encoded FRET with new green and red fluorescent proteins" at the meeting "Forster Resonance Energy Transfer in Life Sciences" at the Max-Planck Institute in Gottingen, Germany.
Yang Geng receives a Spectrum Child Health Pediatric Research Fund Award to study regulation of protein synthesis in neurons. Congrats, Yang!
Graduate student Conor Jacobs joins the lab.
Michael Lin gives a talk at the "next generation of optogenetic tools" minisymposium at the Society for Neuroscience meeting in San Diego.
Dr. Jun Chu joins the lab as a postdoctoral scholar.
Veronica Rangel-Alarcon leaves the lab to start graduate school in environmental engineering. Good luck, Veronica!
The Lin Lab goes on their first annual Hill Hike at Castle Rock State Park, then crowds into Little Hunan Restaurant for dinner.
Xin Zhou joins the lab as an undergraduate visiting researcher.
Alec Perez joins the lab as a Amgen Student Summer Research Program participant.
The Lin Lab has been awarded a CBIS seed grant to develop far-red fluorescent proteins for animal imaging. Thank you, CBIS!
Graduate student Amy Lam joins the lab.
Dr. Yang Geng joins the lab as a postdoctoral scholar.
The Lin Lab starts up with Dr. Yunwen Huo and Veronica Rangel-Alarcon, research associates.