Members of the Life Science Alliance

 

At the core of the Alliance are our Members  - faculty from EMBL and the Stanford University School of Medicine. Their combined expertise spans a broad spectrum of life science research from structural biology and bioinformatics, to chemistry, imaging and genomics. They are committed to the exchange of information to solve complex biomedical challenges together

Check out our active projects, and the research interests of our members below.

Monther Abu-Remaileh

Projects:

The molecular bases of lysosome dysfunction in neurodegenerative diseases

Alex Bateman

Projects:

Pedro Beltrao

Research Interests:

Function and evolution of post-translational networks, evolution of chemical-genetic and genetic-interaction networks.

Carolyn Bertozzi

Projects:

Peer Bork

Research Interests:

Microbiomics and computational biology.

Howard Chang

Projects:

Mike Cherry

Projects:

Wah Chiu

Research Interests:

The development of cryo-EM methodology to determine 3D cellular structures. We also work on the EMDataResource which is an open access database for 3D EM for developing software, data standards and validation methods.

Isidro Cortes Ciriano

Research Interests:

Cancer genomics, single-cell genomics, early detection, spatial genomics, and artificial intelligence for genomics and drug discovery.

Ron Davis

Projects:

Utkan Demirci

Projects:

Jan Ellenberg

Projects:

Advancing imaging technology

Dean Felsher

Research Interests:

How oncogenes initiate and sustain tumoigenesis including: how oncogene activation causes tumor regression, and how tumors escape dependence on oncogenes.

Judith Frydman

Research Interests:

Understanding protein folding including: function and mechanism of chaperones, chaperone networks, ribosome biogenesis, co-translational folding, protein folding homeostasis, misfolding and aggregation disease.

Margaret Fuller

Research Interests:

Regulation of self-renewal, proliferation and differentiation in adult stem cell lineages: including regulation of cell type specific transcription programs, cell-cell communication, and the role of differential mRNA processing and translational control in progression from one cell state to the next.

Eileen Furlong

Research Interests:

Genome regulation and topology during embryonic development including: chromatin topology, chromatin remodelling during cell fate decisions, variation and plasticity in regulatory networks, developmental enhancers, and single cell genomics.

Matthias Hentze

Research Interests:

Using biochemical and systems-level approaches to investigate the connections between gene expression and cell metabolism, and their roles in human disease.

Edith Heard

Projects:

Keith Hodgson

Projects:

Susan Holmes

Projects:

KC Huang

Projects:

Wolfgang Huber

Projects:

Martin Jechlinger

Research Interests:

Mechanisms of oncogene dependence and tumor relapse including studying: when and how cells escape targeted therapies, the molecular properties distinguishing surviving-residual and native cells, and manipulation of the survival mechanism for dormant cells. 

Arnaud Krebs

Research Interests:

Decoding gene regulation using single molecule genomics.  Enabling global measurement of regulatory events in single cells and single DNA molecules, and developing methodologies to perform large-scale genetic manipulations to dissect the function of regulatory DNA in vivo.

Jan Korbel

Project:

Somatic mosaicisms with Alex Urban

Brian Kobilka

Research Interests:

Characterizing the structure and mechanism of G-Protein Coupled Receptors (GPCRs)

Anshul Kundaje

Projects:

Jin Billy Li

Research Interests:

RNA editing. We are interested in ADAR-mediated RNA editing, for both its biological function in dsRNA-mediated innate immunity and its utility as a tool for transcriptome engineering.

Julia Mahamid

Research Interests:

We employ state-of-the-art cellular cryo-electron tomography to study phase-separated assemblies in cell biology and to advance our understanding of the molecular organization of the cytoplasm.

José Márquez

Research Interests:

We develop methods and software for high-throughput, automated crystallography and use them to study the structure of sensing and signalling molecules.

Rob Meijers

Projects:

Tobias Meyer

Projects:

Advancing imaging technology

Stephen Montgomery

Projects:

Robert Prevedel

Research Interests:

Advanced optical techniques for deep tissue microscopy. In particular, we work in the fields of multi-photon microscopy, active wave-front shaping, photo-acoustics as well as computational imaging. Looking for collaboration in cell & developmental biology and neuroscience, where our novel imaging approaches can give new insights.

Marlene Rabinovitch

Projects:

Multiomics for pulmonary hypertension

Gavin Sherlock

Research Interests:

Using high throughput experimental and computational approaches to study adaptive evolution and genetic interaction in yeast

Yiorgo Skiniotis

Projects:

Mike Snyder

Projects:

Genetic regulation of chromatin

Oliver Stegle

Projects:

Lars Steinmetz

Projects:

Aaron Straight

Research Interests:

Understanding the mechanisms that ensure high fidelity genome maintenance and segregation in eukaryotes including: chromosome biology, cell division and chromatin structure.

Nassos Typas

Projects:

Alex Urban

Projects:

Somatic mosaicisms

Matthias Wilmanns

Projects:

Judith Zaugg

Projects:

Multiomics for pulmonary hypertension

Genetic regulation of chromatin