2013
Giacomini CP, Sun S, Varma S, Shain AH, Giacomini MM, Balagtas J, Sweeney RT, Lai E, Del Vecchio CA, Forster AD, Clarke N, Montgomery KD, Zhu S, Wong AJ, van de Rijn M, West RB, Pollack JR. Breakpoint analysis of transcriptional and genomic profiles uncovers novel gene fusions spanning multiple human cancer types. PLoS Genet. 2013 Apr;9(4):e1003464. doi: 10.1371/journal.pgen.1003464. Epub 2013 Apr 25. PubMed PDF
Lin Z, Khong B, Kwok S, Cao H, West RB, Le QT, Kong CS Human papillomavirus 16 detected in nasopharyngeal carcinomas in Caucasian Americans but not in endemic Southern Chinese patients. Head & Neck. 2013 Apr 25. doi: 10.1002/hed.23362. [Epub ahead of print] PubMed PDF
Sweeney, R.T., Zhang, B., Zhu, S.X., Varma, S., Smith, K.S., Montgomery, S.B., van de Rijn, M., Zehnder, J., West, R.B. Desktop transcriptome sequencing from archival tissue to identify clinically relevant translocations. Am J Surg Pathol. 2013 Apr 16. PubMed PDF
Newburger DE, Kashef-Haghighi D, Weng Z, Salari R, Sweeney RT, Brunner AL, Zhu SX, Guo X, Varma S, Troxell ML, West RB, Batzoglou S, Sidow A. Genome Evolution during Progression to Breast Cancer. Genome Res. 2013 Apr 8. [Epub ahead of print] PubMed PDF
Straessler KM, Jones KB, Hu H, Jin H, van de Rijn M, Capecchi MR. Modeling clear cell sarcomagenesis in the mouse: cell of origin differentiation state impacts tumor characteristics. Cancer Cell. 2013 Feb 11;23(2):215-27. doi: 10.1016/j.ccr.2012.12.019. PubMed PDF
Edris B, Willingham SB, Weiskopf K, Volkmer AK, Volkmer JP, Mühlenberg T, Montgomery KD, Contreras-Trujillo H, Czechowicz A, Fletcher JA, West RB, Weissman IL, van de Rijn M. Anti-KIT monoclonal antibody inhibits imatinib-resistant gastrointestinal stromal tumor growth. Proc Natl Acad Sci U S A. 2013 feb. 4. PubMed PDF
2012
Salari K, Spulak ME, Cuff J, Forster AD, Giacomini CP, Huang S, Ko ME, Lin AY, van de Rijn M, Pollack JR. CDX2 is an amplified lineage-survival oncogene in colorectal cancer. Proc Natl Acad Sci U S A. 2012 Nov 13;109(46):E3196-205. doi: 10.1073/pnas.1206004109. Epub 2012 Oct 29. PubMed PDF
Chisholm KM, Wan Y, Li R, Montgomery KD, Chang HY, West RB. Detection of long non-coding RNA in archival tissue: correlation with polycomb protein expression in primary and metastatic breast carcinoma. PLoS One. 2012;7(10):e47998. doi:10.1371 / Epub 2012 Oct 25. PubMed PDF
Troxell ML, Brunner AL, Neff T, Warrick A, Beadling C, Montgomery K, Zhu S, Corless CL, West RB, Phosphatidylinositol-3-kinase pathway mutations are common in breast columnar cell lesions. Mod Pathol. 2012 Jul;25(7):930-7. doi: 10.1038/modpathol.2012.55. Epub 2012 Mar 30 PubMed PDF
Lee CH, Ali RH, Rouzbahman M, Marino-Enriquez A, Zhu M, Guo X, Brunner AL, Chiang S, Leung S, Nelnyk N, Huntsman DG, Blake Gilks C, Nielsen TO, Cin PD, van de Rijn M, Oliva E, Fletcher JA, Nucci MR. Cyclin D1 as a Diagnostic Immunomarker for Endometrial Stromal Sarcoma With YWHAE-FAM22 Rearrangement. Am J Surg Pathol. 2012 Oct;36(10):1562-1570. PubMed PDF
Alayne L Brunner, Andrew H Beck, Badreddin Edris, Robert T Sweeney, Shirley X Zhu, Rui Li, Kelli Montgomery, Sushama Varma, Thea Gilks, Xiangqian Guo, Joseph W Foley, Daniela M Witten, Craig P Giacomini, Ryan A Flynn, Jonathan R Pollack, Robert Tibshirani, Howard Y Chang, Matt van de Rijn and Robert B West. Transcriptional profiling of lncRNAs and novel transcribed regions across a diverse panel of archived human cancers Genome Biol. 2012 Aug 28;13(8):R75. PubMed PDF
Badreddin Edris, Jonathan A. Fletcher, Robert B. West, Matt van de Rijn, and Andrew H. Beck. Comparative Gene Expression Profiling of Benign and Malignant Lesions Reveals Candidate Therapeutic Compounds for Leiomyosarcoma Sarcoma. 2012;2012:805614. Epub 2012 Aug 5. PubMed PDF
Badreddin Edris, Kipp Weiskopf, Irving L. Weissman and Matt van de Rijn. Flipping the script on macrophages in leiomyosarcoma. Oncoimmunology,Volume 1, Issue 8 November 2012. PDF
Kaplan JS, Schnitt SJ, Collins LC, Wang Y, Garber JE, Montgomery K, West RB, Krag K, Fetten K, Lincoln A, Tung NM. Pathologic Features and Immunophenotype of Estrogen Receptor-positive Breast Cancers in BRCA1 Mutation Carriers. Am J Surg Pathol. 2012 May 17. PubMed PDF
Karamchandani JR, Nielsen TO, van de Rijn M, West RB. Sox10 and S100 in the Diagnosis of Soft-tissue Neoplasms. Appl Immunohistochem Mol Morphol. 2012 Apr 10. PubMed PDF
Lee CH, Mariño-Enriquez A, Ou W, Zhu M, Ali RH, Chiang S, Amant F, Gilks CB, van de Rijn M, Oliva E, Debiec-Rychter M, Dal Cin P, Fletcher JA, Nucci MR. The Clinicopathologic Features of YWHAE-FAM22 Endometrial Stromal Sarcomas: A Histologically High-grade and Clinically Aggressive Tumor. Am J Surg Pathol. 2012 May;36(5):641-53. PubMed PDF
Willingham SB, Volkmer JP, Gentles AJ, Sahoo D, Dalerba P, Mitra SS, Wang J, Contreras-Trujillo H, Martin R, Cohen JD, Lovelace P, Scheeren FA, Chao MP, Weiskopf K, Tang C, Volkmer AK, Naik TJ, Storm TA, Mosley AR, Edris B, Schmid SM, Sun CK, Chua MS, Murillo O, Rajendran P, Cha AC, Chin RK, Kim D, Adorno M, Raveh T, Tseng D, Jaiswal S, Enger PO, Steinberg GK, Li G, So SK, Majeti R, Harsh GR, van de Rijn M, Teng NN, Sunwoo JB, Alizadeh AA, Clarke MF, Weissman IL. The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. Proc Natl Acad Sci U S A. 2012 Mar 26. doi:10.1073 PubMed PDF
Edris B, Weiskopf K, Volkmer AK, Volkmer JP, Willingham SB, Contreras-Trujillo H, Liu J, Majeti R, West RB, Fletcher JA, Beck AH, Weissman IL, van de Rijn M. Antibody therapy targeting the CD47 protein is effective in a model of aggressive metastatic leiomyosarcoma. Proc Natl Acad Sci U S A. 2012 Mar 26. [Epub ahead of print] PubMed PDF
Volkmer JP, Sahoo D, Chin RK, Ho PL, Tang C, Kurtova AV, Willingham SB, Pazhanisamy SK, Contreras-Trujillo H, Storm TA, Lotan Y, Beck AH, Chung BI, Alizadeh AA, Godoy G, Lerner SP, van de Rijn M, Shortliffe LD, Weissman IL, Chan KS. Three differentiation states risk-stratify bladder cancer into distinct subtypes. Proc Natl Acad Sci U S A. 2012 Feb 7;109(6):2078-83. PubMed PDF
Lee CH, Ou WB, Mariño-Enriquez A, Zhu M, Mayeda M, Wang Y, Guo X, Brunner AL, Amant F, French CA, West RB, McAlpine JN, Gilks CB, Yaffe MB, Prentice LM, McPherson A, Jones SJ, Marra MA, Shah SP, van de Rijn M, Huntsman DG, Dal Cin P, Debiec-Rychter M, Nucci MR, Fletcher JA. 14-3-3 fusion oncogenes in high-grade endometrial stromal sarcoma. Proc Natl Acad Sci U S A. 2012 Jan 5. PubMed PDF
Badreddin Edris, Iñigo Espinosa, Thomas Mühlenberg, Amanda Mikels, Cheng-Han Lee, Sonja E. Steigen, Shirley Zhu, Kelli D. Montgomery, Alexander J.F. Lazar, Dina Lev, Jonathan A. Fletcher, Andrew H. Beck, Robert B. West, Roel Nusse, Matt van de Rijn, ROR2 is a Novel Prognostic Biomarker and a Potential Therapeutic Target in Leiomyosarcoma and Gastrointestinal Stromal Tumour. J Pathol. 2012 Jan 4. doi: 10.1002/path.3986 PubMed PDF
2011
Beck AH, Sangoi AR, Leung S, Marinelli RJ, Nielsen TO, van de Vijver MJ, West RB, van de Rijn M, Koller D., Systematic analysis of breast cancer morphology uncovers stromal features associated with survival. Sci Transl Med. 2011 Nov 9;3(108):108ra113. PubMed PDF
Kwei KA, Shain AH, Bair R, Montgomery K, Karikari CA, van de Rijn M, Hidalgo M, Maitra A, Bashyam MD, Pollack JR., SMURF1 Amplification Promotes Invasiveness in Pancreatic Cancer. PLoS One. 2011;6(8):e23924. Epub 2011 Aug 22. PubMed PDF
Espinosa I, Edris B, Lee CH, Wei Cheng H, Gilks CB, Wang Y, Montgomery KD, Varma S, Li R, Marinelli RJ, West RB, Nielsen T, Beck AH, van de Rijn M. CSF1 Expression in Nongynecological Leiomyosarcoma Is Associated with Increased Tumor Angiogenesis. Am J Pathol. 2011 Aug 18 PubMed PDF
Colombo C, Creighton CJ, Ghadimi MP, Bolshakov S, Warneke CL, Zhang Y, Lusby K, Zhu S, Lazar AJ, West RB, de Rijn MV, Lev D. Increased midkine expression correlates with desmoid tumour recurrence: a potential biomarker and therapeutic target. J Pathol. 2011 Jun 10. doi: 10.1002/path.295. PubMed PDF
Malhotra S, Lapointe J, Salari K, Higgins JP, Ferrari M, Montgomery K, van de Rijn M, Brooks JD, Pollack JR. A tri-marker proliferation index predicts biochemical recurrence after surgery for prostate cancer. PLoS One. 2011;6(5):e20293. Epub 2011 May 23 PubMed PDF
Sangoi AR, Fujiwara M, West RB, Montgomery KD, Bonventre JV, Higgins JP, Rouse RV, Gokden N, McKenney JK., Immunohistochemical distinction of primary adrenal cortical lesions from metastatic clear cell renal cell carcinoma: a study of 248 cases, Am J Surg Pathol. 2011 May;35(5):678-86, PubMed PDF
Mills AM, Beck AH, Montgomery KD, Zhu SX, Espinosa I, Lee CH, Subramanian S, Fletcher CD, van de Rijn M, West RB. Expression of subtype-specific group 1 leiomyosarcoma markers in a wide variety of sarcomas by gene expression analysis and immunohistochemistry.
Am J Surg Pathol. 2011 Apr;35(4):583-9.
PubMed PDF
Lin AY, Chua MS, Choi YL, Yeh W, Kim YH, Azzi R, Adams GA, Sainani K, van de Rijn M, So SK, Pollack JR. Comparative Profiling of Primary Colorectal Carcinomas and Liver Metastases Identifies LEF1 as a Prognostic Biomarker. PLoS One. 2011 Feb 24;6(2):e16636. PubMed PDF
Wu JM, Beck AH, Pate LL, Witten D, Zhu S, Montgomery KD, Allison KH, van de Rijn M, West RB. Endogenous versus tumor-specific host response to breast carcinoma: a study of stromal response in synchronous breast primaries and biopsy site changes. Clin Cancer Res. 2011 Feb 1;17(3):437-46. Epub 2010 Nov 22.. PubMed PDF
West RB, Kong C, Clarke N, Gilks T, Lipsick JS, Cao H, Kwok S, Montgomery KD, Varma S, Le QT. MYB expression and translocation in adenoid cystic carcinomas and other salivary gland tumors with clinicopathologic correlation. Am J Surg Pathol. 2011 Jan;35(1):92-9. PubMed PDF
2010
West RB. Expression profiling in soft tissue sarcomas with emphasis on synovial sarcoma, gastrointestinal stromal tumor, and leiomyosarcoma. Adv Anat Pathol. 2010 Sep;17(5):366-73. PubMed PDF
Pradhan M, Risberg BA, Tropé CG, van de Rijn M, Gilks CB, Lee CH. Gross genomic alterations and gene expression profiles of high- grade serous carcinoma of the ovary with and without BRCA1 inactivation. BMC Cancer. 2010 Sep 15;10:493. PubMed PDF
Sharma M, Beck AH, Webster JA, Espinosa I, Montgomery K, Varma S, van de Rijn M, Jensen KC, West RB, Analysis of stromal signatures in the tumor microenvironment of ductal carcinoma in situ. Breast Cancer Res Treat. 2010 Sep;123(2):397-404. Epub 2009 Dec 1. PubMed PDF
Boiko AD, Razorenova OV, van de Rijn M, Swetter SM, Johnson DL, Ly DP, Butler PD, Yang GP, Joshua B, Kaplan MJ, Longaker MT, Weissman IL. Human melanoma-initiating cells express neural crest nerve growth factor receptor CD271. Nature. 2010 Jul 1;466(7302):40-1. PubMed
Lopes LF, West RB, Bacchi LM, van de Rijn M, Bacchi CE. DOG1 for the diagnosis of gastrointestinal stromal tumor (GIST): Comparison between 2 different antibodies. Appl Immunohistochem Mol Morphol. 2010 Jul;18(4):333-7. PubMed PDF
Webster JA, Beck AH, Sharma M, Espinosa I, Weigelt B, Schreuder M, Montgomery KD, Jensen KC, van de Rijn M, West R. Variations in stromal signatures in breast and colorectal cancer metastases. J Pathol. 2010 May 21. [Epub ahead of print] PubMed PDF
Nielsen TO, West RB. Translating gene expression into clinical care: sarcomas as a paradigm.J Clin Oncol. 2010 Apr 1;28(10):1796-805. Epub 2010 Mar 1. PubMed PDF
Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, Wang Y, Brzoska P, Kong B, Li R, West RB, van de Vijver MJ, Sukumar S, Chang HY., Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature. 2010 Apr 15;464(7291):1071-6. PubMed PDF
Andrew H. Beck., Ziming Weng., Daniela M. Witten, Shirley Zhu, Joseph W. Foley, Phil
Lacroute, Cheryl L. Smith, Robert Tibshirani, Matt van de Rijn, Arend Sidow, Robert B.West, 3'-End Sequencing for Expression Quantification (3SEQ) from Archival Tumor Samples. PLoS One. 2010 Jan 19;5(1):e8768. PubMed PDF
Beck AH, Lee CH, Witten DM, Gleason BC, Edris B, Espinosa I, Zhu S, Li R, Montgomery KD, Marinelli RJ, Tibshirani R, Hastie T, Jablons DM, Rubin BP, Fletcher CD, West RB, van de Rijn M. Discovery of molecular subtypes in leiomyosarcoma through integrative molecular profiling. Oncogene. 2010 Feb 11;29(6):845-54. Epub 2009 Nov 9. PubMed PDF
Subramanian S, Thayanithy V, West RB, Lee CH, Beck AH, Zhu S, Downs-Kelly E, Montgomery K, Goldblum JR, Hogendoorn PC, Corless CL, Oliveira AM, Dry SM, Nielsen TO, Rubin BP, Fletcher JA, Fletcher CD, van de Rijn M. Genome-wide transcriptome analyses reveal p53 inactivation mediated loss of miR-34a expression in malignant peripheral nerve sheath tumours. J Pathol. 2010 Jan;220(1):58-70. PubMed PDF
2009
Lee CH, Subramanian S, Beck AH, Espinosa I, Senz J, Zhu SX, Huntsman D, van de Rijn M, Gilks CB. MicroRNA profiling of BRCA1/2 mutation-carrying and non-mutation-carrying high-grade serous carcinomas of ovary. PLoS One. 2009 Oct 2;4(10):e7314 PubMed PDF
Lee CH, Turbin DA, Sung YC, Espinosa I, Montgomery K, van de Rijn M, Gilks CB. A panel of antibodies to determine site of origin and malignancy in smooth muscle tumors. Mod Pathol. 2009 Dec;22(12):1519-31. Epub 2009 Sep 4. PubMed PDF
Chan KS, Espinosa I, Chao M, Wong D, Ailles L, Diehn M, Gill H, Presti J Jr, Chang HY, van de Rijn M, Shortliffe L, Weissman IL. Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc Natl Acad Sci U S A. 2009 Aug 18;106(33):14016-21. Epub 2009 Aug 4. PubMed PDF
Pires de Camargo V, van de Rijn M, de Alava E, Madoz-Gúrpide J, Pilotti S, von Mehren M, Pedeutour F, Maki RG, Rutkowski P, Thomas DM. Other targetable sarcomas. Semin Oncol. 2009 Aug;36(4):358-71. PubMed PDF
Espinosa I, Beck AH, Lee CH, Zhu S, Montgomery KD, Marinelli RJ, Ganjoo KN, Nielsen TO, Gilks CB, West RB, van de Rijn M. Coordinate expression of colony-stimulating factor-1 and colony-stimulating factor-1-related proteins is associated with poor prognosis in gynecological and nongynecological leiomyosarcoma. Am J Pathol. 2009 Jun;174(6):2347-56. Epub 2009 May 14. PubMed PDF
Jensen KC, Nielsen TO, Gilks CB, West RB. HER2 Intermediate Breast Cancers. Am J Surg Pathol. 2009 Nov;33(11):1739; author reply 1739-40. PubMed PDF
Turashvili G, Leung S, Turbin D, Montgomery K, Gilks B, West R, Carrier M, Huntsman D, Aparicio S. Inter-observer reproducibility of HER2 immunohistochemical assessment and concordance with fluorescent in situ hybridization (FISH): pathologist assessment compared to quantitative image analysis. BMC Cancer. 2009 May 29;9:165. PubMed PDF
Pai RK, West RB. MOC-31 exhibits superior reactivity compared with Ber-EP4 in invasive lobular and ductal carcinoma of the breast: a tissue microarray study. Appl Immunohistochem Mol Morphol. 2009 May;17(3):202-6. PubMed PDF
Beck AH, West RB, van de Rijn M. Gene expression profiling for the investigation of soft tissue sarcoma pathogenesis and the identification of diagnostic, prognostic, and predictive biomarkers. Virchows Arch. 2010 Feb;456(2):141-51. Epub 2009 May 2. PubMed PDF
Gomez-Pinilla PJ, Gibbons SJ, Bardsley MR, Lorincz A, Pozo MJ, Pasricha PJ, Van de Rijn M, West RB, Sarr MG, Kendrick ML, Cima RR, Dozois EJ, Larson DW, Ordog T, Farrugia G.
Ano1 is a selective marker of interstitial cells of Cajal in the human and mouse gastrointestinal tract. Am J Physiol Gastrointest Liver Physiol. 2009 Apr 16. PubMed PDF
Cheng H, Dodge J, Mehl E, Liu S, Poulin N, van de Rijn M, Nielsen TO. Validation of immature adipogenic status and identification of prognostic biomarkers in myxoid liposarcoma using tissue microarrays. Hum Pathol. 2009 Apr 13. PubMed PDF
Ying L, Lau A, Alvira CM, West R, Cann GM, Zhou B, Kinnear C, Jan E, Sarnow P, Van de Rijn M, Rabinovitch M. LC3-mediated fibronectin mRNA translation induces fibrosarcoma growth by increasing connective tissue growth factor. J Cell Sci. 2009 May 1;122(Pt 9):1441-51. Epub 2009 Apr 14. PubMed PDF
Hu Z, Fan C, Livasy C, He X, Oh DS, Ewend MG, Carey LA, Subramanian S, West R, Ikpatt F, Olopade OI, van de Rijn M, Perou CM. A compact VEGF signature associated with distant metastases and poor outcomes. BMC Med. 2009 Mar 16;7:9. PubMed PDF
Beck AH, Espinosa I, Edris B, Li R, Montgomery K, Zhu S, Varma S, Marinelli RJ, van de Rijn M, West RB. The macrophage colony-stimulating factor 1 response signature in breast carcinoma. Clin Cancer Res. 2009 Feb 1;15(3):778-87 PubMed PDF
2008
Clarke B, Tinker AV, Lee CH, Subramanian S, van de Rijn M, Turbin D, Kalloger S, Han G, Ceballos K, Cadungog MG, Huntsman DG, Coukos G, Gilks CB., Intraepithelial T cells and prognosis in ovarian carcinoma: novel associations with stage, tumor type, and BRCA1 loss. Mod Pathol. 2008 Dec 5. PubMed PDF
Beadling C, Jacobson-Dunlop E, Hodi FS, Le C, Warrick A, Patterson J, Town A, Harlow A, Cruz F 3rd, Azar S, Rubin BP, Muller S, West R, Heinrich MC, Corless CL. KIT gene mutations and copy number in melanoma subtypes. Clin Cancer Res. 2008 Nov 1;14(21):6821-8. PubMed PDF
Huang HY, West RB, Tzeng CC, van de Rijn M, Wang JW, Chou SC, Huang WW, Eng HL, Lin CN, Yu SC, Wu JM, Lu CC, Li CF., Immunohistochemical and Biogenetic Features of Diffuse-Type Tenosynovial Giant Cell Tumors: The Potential Roles of Cyclin A, P53, and Deletion of 15q in Sarcomatous Transformation. Clin Cancer Res. 2008 Oct 1;14(19):6023-6032. PubMed PDF
Jensen KC, Schaeffer DF, Cheang M, Montgomery K, West RB, Gilks CB, Ross D, Turashvili G, Schnitt S, van de Rijn M., Characterization of a novel anti-fatty acid synthase (FASN) antiserum in breast tissue. Mod Pathol. 2008 Sep 26. PubMed PDF
Heerema-McKenney A, Wijnaendts LC, Pulliam JF, Lopez-Terrada D, McKenney JK, Zhu S, Montgomery K, Mitchell J, Marinelli RJ, Hart AA, van de Rijn M, Linn SC. Diffuse Myogenin Expression by Immunohistochemistry is an Independent Marker of Poor Survival in Pediatric Rhabdomyosarcoma: A Tissue Microarray Study of 71 Primary Tumors Including Correlation With Molecular Phenotype. Am J Surg Pathol. 2008 Aug 14. PubMed PDF
Kwei KA, Bashyam MD, Kao J, Ratheesh R, Reddy EC, Kim YH, Montgomery K, Giacomini CP, Choi YL, Chatterjee S, Karikari CA, Salari K, Wang P, Hernandez-Boussard T, Swarnalata G, van de Rijn M, Maitra A, Pollack JR. Genomic profiling identifies GATA6 as a candidate oncogene amplified in pancreatobiliary cancer. PLoS Genet. 2008 May 23;4(5):e1000081. PubMed PDF
Lubieniecka JM, de Bruijn DR, Su L, van Dijk AH, Subramanian S, van de Rijn M, Poulin N, van Kessel AG, Nielsen TO. Histone deacetylase inhibitors reverse SS18-SSX-mediated polycomb silencing of the tumor suppressor early growth response 1 in synovial sarcoma. Cancer Res. 2008 Jun 1;68(11):4303-10. PubMed PDF
Jokinen CH, Dadras SS, Goldblum JR, van de Rijn M, West RB, Rubin BP. Diagnostic implications of podoplanin expression in peripheral nerve sheath neoplasms. Am J Clin Pathol. 2008 Jun;129(6):886-93 PubMed PDF
Beck AH, Espinosa I, Gilks CB, van de Rijn M, West RB. The fibromatosis signature defines a robust stromal response in breast carcinoma. Lab Invest. 2008 Jun;88(6):591-601. PubMed PDF
Rinn JL, Wang JK, Liu H, Montgomery K, van de Rijn M, Chang HY. A systems biology approach to anatomic diversity of skin. J Invest Dermatol. 2008 Apr;128(4):776-82. PubMed PDF
S. Subramanian , W. Lui , C. Lee , I. Espinosa , T.O. Nielsen , M. Heinrich , C. Corless , A. Fire , M. van de Rijn. MicroRNA expression signature of human sarcomas. Oncogene, 2008 Mar 27;27(14):2015-26. Epub 2007 Oct 8 . PubMed PDF
Lapointe J, Malhotra S, Higgins JP, Bair E, Thompson M, Salari K, Giacomini CP, Ferrari M, Montgomery K, Tibshirani R, van de Rijn M, Brooks JD, Pollack JR. hCAP-D3 expression marks a prostate cancer subtype with favorable clinical behavior and androgen signaling signature.
Am J Surg Pathol. 2008 Feb;32(2):205-9. PubMed PDF
Cheang MC, van de Rijn M, Nielsen TO. Gene Expression Profiling of Breast Cancer.
Annu Rev Pathol. 2008 Feb 28;3:67-97. PubMed PDF
Cheng-Han Lee, Inigo Espinosa, SuzanVrijaldenhoven, Subbaya Subramanian, Kelli D Montgomery, Shirley Zhu, Robert J Marinelli, Johannes L Peterse , Neal Poulin, Torsten O. Nielsen, Rob B. West, C. Blake Gilks, Matt van de Rijn. Prognostic significance of macrophage infiltration in leiomyosarcomas. Clinic cancer research, 2008 Mar 1;14(5):1423-30 PubMed Web Supplement PDF
I. Espinosa, , C. Lee, M. Kim, B. Rouse, S. Subramanian, K. Montgomery, S. Varna, C.L. Corless, M.C. Heinrich, K.S. Smith, Z. Wang, B. Rubin, T. Nielsen, R. Seitz, D. Ross, R.B. West, M.L. Cleary, M. van de Rijn. A novel monoclonal antibody against DOG1 is a sensitive and specific marker for gastrointestinal stromal tumors. Am J Surg Pathol. 2008 Feb;32(2):210-218 PubMed Web Supplement PDF
C. Lee, I. Espinosa, K. Jensen, S. Subramanian, S. Zhu, S. Varma, K. Montgomery, T.O. Nielsen, M. van de Rijn, R.B. West. Gene expression profiling identifies p63 as a diagnostic marker for giant cell tumor of the bone. Mod Pathol. 2008 Jan 11, PubMed PDF
2007
Marinelli RJ, Montgomery K, Liu CL, Shah NH, Prapong W, Nitzberg M, Zachariah ZK, Sherlock GJ, Natkunam Y, West RB, van de Rijn M, Brown PO, Ball CA. The Stanford Tissue Microarray Database. Nucleic Acids Res. 2007 Nov 22. PubMed PDF
A. Alkushi, B.A. Clarke, M. Akbari, P. Lim, D. Miller, A. Magliocco, A. Coldman, M. van de Rijn, D. Huntsman, R. Parker, C.B. Gilks. Identification of prognostically relevant and reproducible subsets of endometrial adenocarcinoma based on clustering analysis of immunostaining data. Modern Pathology, 2007 Nov;20(11):1156-65. PubMed PDF
Chi JT, Rodriguez EH, Wang Z, Nuyten DS, Mukherjee S, van de Rijn M, van de Vijver MJ, Hastie T, Brown PO. Gene expression programs of human smooth muscle cells: tissue-specific differentiation and prognostic significance in breast cancers. PLoS Genet. 2007 Sep 7;3(9):1770-84. PubMed PDF
A. Alkushi, B.A. Clarke, M. Akbari, P. Lim, D. Miller, A. Magliocco, A. Coldman, M. van de Rijn, D. Huntsman, R. Parker, C.B. Gilks. Identification of prognostically relevant and reproducible subsets of endometrial adenocarcinoma based on clustering analysis of immunostaining data. Modern Pathology, 2007 Nov;20(11):1156-65. Epub 2007 Aug 24 PubMed PDF
D.A. Turbin, S. Leung M.C. Cheang, H.A. Kennecke, K.D. Montgomery, S. McKinney, D.O. Treaba, N. Boyd, L.C. Goldstein, S. Badve, A.M. Gown, M. van de Rijn, T.O. Nielsen, C.B. Gilks, D.G. Huntsman. Automated quantitative analysis of estrogen receptor expression in breast carcinoma does not differ from expert pathologist scoring: a tissue microarray study of 3,484 cases. Breast Cancer Research and Treatment, DOI 10.1007/s10549-007-9736-z PubMed PDF
Cheang MC, van de Rijn M, Nielsen TO. Gene Expression Profiling of Breast Cancer. Annu Rev Pathol. 2007 Aug 15 PubMed
West RB, van de Rijn M., Experimental approaches to the study of cancer-stroma interactions: recent findings suggest a pivotal role for stroma in carcinogenesis. Lab Invest. 2007 Aug 13; PubMed PDF
Cupp JS, Miller MA, Montgomery KD, Nielsen TO, O'Connell JX, Huntsman D, van de Rijn M, Gilks CB, West RB. Translocation and expression of CSF1 in pigmented villonodular synovitis, tenosynovial giant cell tumor, rheumatoid arthritis and other reactive synovitides.
Am J Surg Pathol. 2007 Jun;31(6):970-6. PubMed
Jensen KC, Higgins JP, Montgomery K, Kaygusuz G, van de Rijn M, Natkunam Y.,
The utility of PAX5 immunohistochemistry in the diagnosis of undifferentiated malignant neoplasms.
Mod Pathol. 2007 May 25; PubMed PDF
Higgins JP, Kaygusuz G, Wang L, Montgomery K, Mason V, Zhu SX, Marinelli RJ, Presti JC, van de Rijn M, Brooks JD.,
Placental S100 (S100P) and GATA3: markers for transitional epithelium and urothelial carcinoma discovered by complementary DNA microarray.
Am J Surg Pathol. 2007 May;31(5):673-80. PubMed Web Supplement
Lehman NL, Tibshirani R, Hsu JY, Natkunam Y, Harris BT, West RB, Masek MA, Montgomery K, van de Rijn M, Jackson PK.,
Oncogenic regulators and substrates of the anaphase promoting complex/cyclosome are frequently overexpressed in malignant tumors.
Am J Pathol. 2007 May;170(5):1793-805. PubMed PDF
Terry J, Saito T, Subramanian S, Ruttan C, Antonescu CR, Goldblum JR, Downs-Kelly E, Corless CL, Rubin BP, van de Rijn M, Ladanyi M, Nielsen TO. TLE1 as a Diagnostic Immunohistochemical Marker for Synovial Sarcoma Emerging From Gene Expression Profiling Studies. Am J Surg Pathol 2007; 31: 2: 240-246. PubMed PDF
Lapointe J, Kim YH, Miller MA, Li C, Kaygusuz G, van de Rijn M, Huntsman DG, Brooks JD, Pollack JR. A variant TMPRSS2 isoform and ERG fusion product in prostate cancer with implications for molecular diagnosis. Mod Pathol 2007. PubMed PDF
Lowe AW, Olsen M, Hao Y, Lee SP, Taek Lee K, Chen X, van de Rijn M, Brown PO. Gene expression patterns in pancreatic tumors, cells and tissues. PLoS ONE 2007; 2: e323. PubMed PDF
2006
van de Rijn M, Fletcher JA. Genetics of soft tissue tumors. Annu Rev Pathol. 2006;1:435-66. PubMed
Sneddon JB, Zhen HH, Montgomery K, van de Rijn M, Tward AD, West R, Gladstone H, Chang HY, Morganroth GS, Oro AE, Brown PO.,
Bone morphogenetic protein antagonist gremlin 1 is widely expressed by cancer-associated stromal cells and can promote tumor cell proliferation.
Proc Natl Acad Sci U S A. 2006 Oct 3;103(40):14842-7. Epub 2006 Sep 26. PubMed PDF
Seykora JT, Kutcher C, van de Rijn M, Dzubow L, Junkins-Hopkins J, Ioffreda M.,
Ossifying fibromyxoid tumor of soft parts presenting as a scalp cyst.
J Cutan Pathol. 2006 Aug;33(8):569-72. PubMed PDF
West RB, Rubin BP, Miller MA, Subramanian S, Kaygusuz G, Montgomery K, Zhu S, Marinelli RJ, De Luca A, Downs-Kelly E, Goldblum JR, Corless CL, Brown PO, Gilks CB, Nielsen TO, Huntsman D, van de Rijn M. , A landscape effect in tenosynovial giant-cell tumorfrom activation of CSF1 expression by a translocationin a minority of tumor cells. Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):690-5. PubMed PDF Web Supplement
West RB, van de Rijn M., The role of microarray technologies in the study of soft tissue tumours. Histopathology. 2006 Jan;48(1):22-31. PubMed PDF
2005
Lehman NL, van de Rijn M, Jackson PK. Screening of Tissue Microarrays for Ubiquitin Proteasome System Components in Tumors. Methods Enzymol. 2005;399C:334-355. PubMed PDF
Troxell ML, Schwartz EJ, van de Rijn M, Ross DT, Warnke RA, Higgins JP, Natkunam Y. Follicular dendritic cell immunohistochemical markers in angioimmunoblastic T-cell lymphoma. Appl Immunohistochem Mol Morphol. 2005 Dec;13(4):297-303. PubMed PDF
Liu CL, Montgomery KD, Natkunam Y, West RB, Nielsen TO, Cheang MC, Turbin DA,Marinelli RJ, van de Rijn M, Higgins JP. TMA-Combiner, a simple software tool to permit analysis of replicate cores on tissue microarrays. Mod Pathol. 2005 Sep 16; PubMed PDF Web Supplement
Subbaya Subramanian, Robert B West, Robert J Marinelli, Torsten O Nielsen, Brian P Rubin, John R Goldblum, Rajiv M Patel, Shirley Zhu, Kelli Montgomery, Tony L Ng, Christopher L Corless, Michael C Heinrich and Matt van de Rijn. The gene expression profile of extraskeletal myxoid chondrosarcoma. J Pathol. 2005 May 26. PubMed PDF Web Supplement
R.B. West, D.S.A. Nuyten, S. Subramanian, T.O. Nielsen, C.L. Corless, B.P. Rubin, K.Montgomery, S. Zhu, R. Patel, T. Hernandez-Boussard, J.R. Goldblum, P.O. Brown, M. van de Vijver, M. van de Rijn. Determination of stromal signatures in breast carcinoma. PLOS Biology 2005, 3(6):e187. PubMed Web Supplement PDF
Shyamsundar R, Kim YH, Higgins JP, Montgomery K, Jorden M, Sethuraman A, van de Rijn M, Botstein D, Brown PO, Pollack JR. A DNA microarray survey of gene expression in normal human tissues. Genome Biol. 2005;6(3):R22. Epub 2005 Feb 14. PubMed Web Supplement PDF
F.P. Li, J.A. Fletcher, M. Heinrich, J.E. Garber, S.E. Sallan, S. Higham, C. Curiel-Lewandrowski, A. Duensing, M. van de Rijn, L.E. Schnipper, G.D. Demetri. Familial gastrointestinal stromal tumor syndrome (GISTs): phenotypic and molecular features in a kindred. J Clin Oncol. 2005 Apr 20;23(12):2735-43. PubMed PDF
Montgomery K, Zhao S, van de Rijn M, Natkunam Y. A novel method for making"tissue" microarrays from small numbers of suspension cells. Appl Immunohistochem Mol Morphol. 2005 Mar;13(1):80-4. PubMed PDF
Gilks CB, Vanderhyden BC, Zhu S, van de Rijn M, Longacre TA. Distinction between serous tumors of low malignant potential and serous carcinomas based on global mRNA expression profiling. Gynecol Oncol. 2005 Mar;96(3):684-94.PubMed PDF
Chang HY, Nuyten DS, Sneddon JB, Hastie T, Tibshirani R, Sorlie T, Dai H, He YD, Van't Veer LJ, Bartelink H, van de Rijn M, Brown PO, van de Vijver MJ. Robustness, scalability, and integration of a wound-response gene expression signature in predicting breast cancer survival. Proc Natl Acad Sci U S A. 2005 Feb 8. PubMed PDF Web Supplement
2004
Makretsov NA, Huntsman DG, Nielsen TO, Yorida E, Peacock M, Cheang MC, Dunn SE, Hayes M, van de Rijn M, Bajdik C, Gilks CB. Hierarchical clustering analysis of tissue microarray immunostaining data identifies prognostically significant groups of breast carcinoma. Clin Cancer Res. 2004 Sep 15;10(18 Pt 1):6143-51. PubMed PDF
Nielsen TO, Hsu FD, Jensen K, Cheang M, Karaca G, Hu Z, Hernandez-Boussard T, Livasy C, Cowan D, Dressler L, Akslen LA, Ragaz J, Gown AM, Gilks CB, van de Rijn M, Perou CM. Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res. 2004 Aug 15;10(16):5367-74. PubMed PDF Web Supplement
Subramanian S, West RB, Corless CL, Ou W, Rubin BP, Chu KM, Leung SY, Yuen ST, Zhu S, Hernandez-Boussard T, Montgomery K, Nielsen TO, Patel RM, Goldblum JR, Heinrich MC, Fletcher JA, van de Rijn M. Gastrointestinal stromal tumors (GISTs) with KIT and PDGFRA mutations have distinct gene expression profiles.Oncogene. 2004 Oct 14;23(47):7780-90. PubMed Web Supplement PDF
West RB, Harvell J, Linn SC, Liu CL, Prapong W, Hernandez-Boussard T, Montgomery K, Nielsen TO, Rubin BP, Patel R, Goldblum JR, Brown PO, van de Rijn M. Apo D in soft tissue tumors: a novel marker for dermatofibrosarcoma protuberans.
West RB, Corless CL, Chen X, Rubin BP, Subramanian S, Montgomery K, Zhu S, Ball CA, Nielsen TO, Patel R, Goldblum JR, Brown PO, Heinrich MC, van de Rijn M.The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status. Am J Pathol. 2004 Jul;165(1):107-13.PubMed PDF Web Supplement
Harvell JD, Kohler S, Zhu S, Hernandez-Boussard T, Pollack JR, van de Rijn M. High-resolution array-based comparative genomic hybridization for distinguishing paraffin-embedded Spitz nevi and melanomas. Diagn Mol Pathol. 2004 Mar;13(1):22-5. PubMed PDF Web Supplement
Chen X, Higgins J, Cheung ST, Li R, Mason V, Montgomery K, Fan ST, van de Rijn M, So S. Novel endothelial cell markers in hepatocellular carcinoma.Mod Pathol. 2004 Oct;17(10):1198-210. PubMed PDF
van de Rijn M, Gilks CB. Applications of microarrays to histopathology. Histopathology. 2004 Feb;44(2):97-108. Review. PubMed PDF Web Supplement
Chang HY, Sneddon JB, Alizadeh AA, Sood R, West RB, Montgomery K, Chi JT, van de Rijn M, Botstein D, Brown PO. Gene expression signature of fibroblast serum response predicts human cancer progression: similarities between tumors and wounds.PLoS Biol. 2004 Feb;2(2):E7. Epub 2004 Jan 13. PubMed Web Supplement
Lapointe J, Li C, Higgins JP, van de Rijn M, Bair E, Montgomery K, Ferrari M, Egevad L, Rayford W, Bergerheim U, Ekman P, DeMarzo AM, Tibshirani R, Botstein D, Brown PO, Brooks JD, Pollack JR. Gene expression profiling identifies clinically relevant subtypes of prostate cancer. Proc Natl Acad Sci U S A. 2004 Jan 20;101(3):811-6. Epub 2004 Jan 07. PubMed Web Supplement
Higgins JP, Wang L, Kambham N, Montgomery K, Mason V, Vogelmann SU, Lemley KV, Brown PO, Brooks JD, van de Rijn M. Gene expression in the normal adult human kidney assessed by complementary DNA microarray. Mol Biol Cell. 2004 Feb;15(2):649-56. Epub 2003 Dec 02.
2003Linn SC, West RB, Pollack JR, Zhu S, Hernandez-Boussard T, Nielsen TO, Rubin BP, Patel R, Goldblum JR, Siegmund D, Botstein D, Brown PO, Gilks CB, van de Rijn M. Gene expression patterns and gene copy number changes in dermatofibrosarcoma protuberans. Am J Pathol. 2003 Dec;163(6):2383-95. PubMed Web Supplement PDF
Nielsen TO, Hsu FD, O'Connell JX, Gilks CB, Sorensen PH, Linn S, West RB, Liu CL, Botstein D, Brown PO, van de Rijn M. Tissue microarray validation of epidermal growth factor receptor and SALL2 in synovial sarcoma with comparison to tumors of similar histology. Am J Pathol. 2003 Oct;163(4):1449-56. PubMed
Chi JT, Chang HY, Haraldsen G, Jahnsen FL, Troyanskaya OG, Chang DS, Wang Z, Rockson SG, van de Rijn M, Botstein D, Brown PO. Endothelial cell diversity revealed by global expression profiling. Proc Natl Acad Sci U S A. 2003 Sep 16;100(19):10623-8. Epub 2003 Sep 08. PubMed
Schaner ME, Ross DT, Ciaravino G, Sorlie T, Troyanskaya O, Diehn M, Wang YC, Duran GE, Sikic TL, Caldeira S, Skomedal H, Tu IP, Hernandez-Boussard T, Johnson SW, O'Dwyer PJ, Fero MJ, Kristensen GB, Borresen-Dale AL, Hastie T, Tibshirani R, van de Rijn M, Teng NN, Longacre TA, Botstein D, Brown PO, Sikic BI. Gene expression patterns in ovarian carcinomas. Mol Biol Cell. 2003 Nov;14(11):4376-86. Epub 2003 Sep 05. Pubmed Web Supplement
Linn SC, van de Rijn M, Giaccone G. [Novel approaches; improved diagnostics and therapeutics with DNA microarrays. II. Applications] Ned Tijdschr Geneeskd. 2003 Apr 26;147(17):800-4. Review. Dutch. Linn SC, van de Rijn M, Giaccone G. [Novel approaches; improved diagnosis and therapy with DNA microarrays. I. Technology and data analysis]Ned Tijdschr Geneeskd. 2003 Apr 26;147(17):795-9. Review. Dutch. PubMed
Storz MN, van de Rijn M, Kim YH, Mraz-Gernhard S, Hoppe RT, Kohler S. Gene expression profiles of cutaneous B cell lymphoma. J Invest Dermatol. 2003 May;120(5):865-70. PubMed
Wapnir IL, van de Rijn M, Nowels K, Amenta PS, Walton K, Montgomery K, Greco RS, Dohan O, Carrasco N. Immunohistochemical profile of the sodium/iodide symporter in thyroid, breast, and other carcinomas using high density tissue microarrays and conventional sections. J Clin Endocrinol Metab. 2003 Apr;88(4):1880-8.PubMed
Alkushi A, Irving J, Hsu F, Dupuis B, Liu CL, van de Rijn M, Gilks CB. Immunoprofile of cervical and endometrial adenocarcinomas using a tissue microarray. Virchows Arch. 2003 Mar;442(3):271-7. Epub 2003 Feb 12. PubMed
Higgins JP, Shinghal R, Gill H, Reese JH, Terris M, Cohen RJ, Fero M, Pollack JR, van de Rijn M, Brooks JD. Gene expression patterns in renal cell carcinoma assessed by complementary DNA microarray. Am J Pathol. 2003 Mar;162(3):925-32. PubMed Web Supplement
Fan Z, van de Rijn M, Montgomery K, Rouse RV. Hep par 1 antibody stain for the differential diagnosis of hepatocellular carcinoma: 676 tumors tested using tissue microarrays and conventional tissue sections.Mod Pathol. 2003 Feb;16(2):137-44. PubMed
Higgins JP, Montgomery K, Wang L, Domanay E, Warnke RA, Brooks JD, van de Rijn M. Expression of FKBP12 in benign and malignant vascular endothelium: an immunohistochemical study on conventional sections and tissue microarrays.Am J Surg Pathol. 2003 Jan;27(1):58-64. PubMed
2002Hsu FD, Nielsen TO, Alkushi A, Dupuis B, Huntsman D, Liu CL, van de Rijn M, Gilks CB. Tissue microarrays are an effective quality assurance tool for diagnostic immunohistochemistry. Mod Pathol. 2002 Dec;15(12):1374-80. PubMed
van de Rijn M., Perou CM, Tibshirani R, Haas P, Kallioniemi O, Kononen J, Torhorst J, Sauter G, Zuber M, Kochli OR, Mross F, Dieterich H, Seitz R, Ross D, Botstein D, Brown P. Expression of cytokeratins 17 and 5 identifies a group of breast carcinomas with poor clinical outcome. Am J Pathol. 2002 Dec;161(6):1991-6. Erratum in: Am J Pathol. 2003 Jul;163(1):377. PubMed
Liu CL, Prapong W, Natkunam Y, Alizadeh A, Montgomery K, Gilks CB, van de Rijn M. Software tools for high-throughput analysis and archiving of immunohistochemistry staining data obtained with tissue microarrays. Am J Pathol. 2002 Nov;161(5):1557-65 PubMed Web Supplement
van de Rijn M, Rubin BP. Gene expression studies on soft tissue tumors. Am J Pathol. 2002 Nov;161(5):1531-4. PubMed
Chang HY, Chi JT, Dudoit S, Bondre C, van de Rijn M, Botstein D, Brown PO. Diversity, topographic differentiation, and positional memory in human fibroblasts.Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12877-82. Epub 2002 Sep 24. PubMed Web Supplement
Pollack JR, van de Rijn M, Botstein D. Challenges in developing a molecular characterization of cancer. Semin Oncol. 2002 Jun;29(3):280-5. Review. PubMe
Chen X, Cheung ST, So S, Fan ST, Barry C, Higgins J, Lai KM, Ji J, Dudoit S, Ng IO, Van De Rijn M, Botstein D, Brown PO Gene expression patterns in human liver cancers. Mol Biol Cell. 2002 Jun;13(6):1929-39. PubMed Web Supplement
Nielsen TO, West RB, Linn SC, Alter O, Knowling MA, O'Connell JX, Zhu S, Fero M, Sherlock G, Pollack JR, Brown PO, Botstein D, van de Rijn M. Molecular characterisation of soft tissue tumours: a gene expression study. Lancet. 2002 Apr 13;359(9314):1301-7. PubMed Web Supplement
Garber ME, Troyanskaya OG, Schluens K, Petersen S, Thaesler Z, Pacyna-Gengelbach M, van de Rijn M, Rosen GD, Perou CM, Whyte RI, Altman RB, Brown PO, Botstein D, Petersen I. Diversity of gene expression in adenocarcinoma of the lung.Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13784-9. Epub 2001 Nov 13. Erratum in: Proc Natl Acad Sci U S A 2002 Jan 22;99(2):1098. PubMed Web Supplement
2001
Goldsmith JD, van de Rijn M, Syed N. Orbital hemangiopericytoma and solitary fibrous tumor: a morphologic continuum. Int J Surg Pathol. 2001 Oct;9(4):295-302. PubMed
Alizadeh AA, Ross DT, Perou CM, van de Rijn M. Towards a novel classification of human malignancies based on gene expression patterns.J Pathol. 2001 Sep;195(1):41-52. Review. PubMed
Sorlie T, Perou CM, Tibshirani R, Aas T, Geisler S, Johnsen H, Hastie T, Eisen MB, van de Rijn M, Jeffrey SS, Thorsen T, Quist H, Matese JC, Brown PO, Botstein D, Eystein Lonning P, Borresen-Dale AL. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10869-74. PubMed
Natkunam Y, Warnke RA, Montgomery K, Falini B, van De Rijn M. Analysis of MUM1/IRF4 protein expression using tissue microarrays and immunohistochemistry. Mod Pathol. 2001 Jul;14(7):686-94. PubMed
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2000
Mehlhop PD, van de Rijn M, Brewer JP, Kisselgof AB, Geha RS, Oettgen HC, Martin TR. CD40L, but not CD40, is required for allergen-induced bronchial hyperresponsiveness in mice.Am J Respir Cell Mol Biol. 2000 Nov;23(5):646-51. PubMed
Perou CM, Sorlie T, Eisen MB, van de Rijn M, Jeffrey SS, Rees CA, Pollack JR, Ross DT, Johnsen H, Akslen LA, Fluge O, Pergamenschikov A, Williams C, Zhu SX, Lonning PE, Borresen-Dale AL, Brown PO, Botstein D. Molecular portraits of human breast tumours. Nature. 2000 Aug 17;406(6797):747-52.PubMed Web Supplement
Higgins JP, van de Rijn M, Jones CD, Zehnder JL, Warnke RA. Peripheral T-cell lymphoma complicated by a proliferation of large B cells. Am J Clin Pathol. 2000 Aug;114(2):236-47. PubMed
Ross DT, Scherf U, Eisen MB, Perou CM, Rees C, Spellman P, Iyer V, Jeffrey SS, van de Rijn M, Waltham M, Pergamenschikov A, Lee JC, Lashkari D, Shalon D, Myers TG, Weinstein JN, Botstein D, Brown PO. Systematic variation in gene expression patterns in human cancer cell lines. Nat Genet. 2000 Mar;24(3):227-35. PubMed
Natkunam Y, Rouse RV, Zhu S, Fisher C, van De Rijn M. Immunoblot analysis of CD34 expression in histologically diverse neoplasms. Am J Pathol. 2000 Jan;156(1):21-7. PubMed
1999
Kamel OW, Holly EA, van de Rijn M, Lele C, Sah A. A population based, case control study of non-Hodgkin's lymphoma in patients with rheumatoid arthritis. J Rheumatol. 1999 Aug;26(8):1676-80. PubMed
Perou CM, Jeffrey SS, van de Rijn M, Rees CA, Eisen MB, Ross DT, Pergamenschikov A, Williams CF, Zhu SX, Lee JC, Lashkari D, Shalon D, Brown PO, Botstein D. Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9212-7. PubMed
van de Rijn M, Barr FG, Collins MH, Xiong QB, Fisher C. Absence of SYT-SSX fusion products in soft tissue tumors other than synovial sarcoma. Am J Clin Pathol. 1999 Jul;112(1):43-9. PubMed
Sanders ME, van de Rijn M, Barr FG. Detection of a variant SYT-SSX1 fusion in a case of predominantly epithelioid synovial sarcoma.Mol Diagn. 1999 Mar;4(1):65-70. PubMed
Krasinskas AM, Rosato EF, Partington MT, Whalen CJ, Reynolds C, van de Rijn M, Montone KT. Colonic adenocarcinoma presenting as supraclavicular lymphadenopathy in a 26-yr-old man: a case report. Am J Gastroenterol. 1999 Jan;94(1):282-3. PubMed
van de Rijn M, Barr FG, Xiong QB, Hedges M, Shipley J, Fisher C. Poorly differentiated synovial sarcoma: an analysis of clinical, pathologic, and molecular genetic features.Am J Surg Pathol. 1999 Jan;23(1):106-12. PubMed
1998
McLane MP, Haczku A, van de Rijn M, Weiss C, Ferrante V, MacDonald D, Renauld JC, Nicolaides NC, Holroyd KJ, Levitt RC. Interleukin-9 promotes allergen-induced eosinophilic inflammation and airway hyperresponsiveness in transgenic mice. Am J Respir Cell Mol Biol. 1998 Nov;19(5):713-20. PubMed
Judkins AR, Montone KT, LiVolsi VA, van de Rijn M. Sensitivity and specificity of antibodies on necrotic tumor tissue. Am J Clin Pathol. 1998 Nov;110(5):641-6. PubMed
van de Rijn M, Mehlhop PD, Judkins A, Rothenberg ME, Luster AD, Oettgen HC. A murine model of allergic rhinitis: studies on the role of IgE in pathogenesis and analysis of the eosinophil influx elicited by allergen and eotaxin. J Allergy Clin Immunol. 1998 Jul;102(1):65-74. PubMed
Hunt JL, van de Rijn M, Gupta PK. Immunohistochemical analysis of gel-transferred cells in cytologic preparations following smear division. Diagn Cytopathol. 1998 May;18(5):377-80. PubMed
1997van de Rijn M, Barr FG, Xiong QB, Salhany KE, Fraker DL, Fisher C. Radiation-associated synovial sarcoma. Hum Pathol. 1997 Nov;28(11):1325-8. PubMed
van de Rijn M, Bhargava V, Molina-Kirsch H, Carlos-Bregni R, Warnke RA, Cleary ML, Kamel OW. Extranodal head and neck lymphomas in Guatemala: high frequency of Epstein-Barr virus-associated sinonasal lymphomas. Hum Pathol. 1997 Jul;28(7):834-9. PubMed
Salhany KE, van de Rijn M, Montone KT, Tomaszewski JE. CD5 immunostaining of lymphoid neoplasms in paraffin sections. Am J Clin Pathol. 1997 Apr;107(4):496; author reply 497. PubMed
Mehlhop PD, van de Rijn M, Goldberg AB, Brewer JP, Kurup VP, Martin TR, Oettgen HC. Allergen-induced bronchial hyperreactivity and eosinophilic inflammation occur in the absence of IgE in a mouse model of asthma. Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1344-9. PubMed
van de Rijn M, Kamel OW, Chang PP, Lee A, Warnke RA, Salhany KE. Primary low-grade endometrial B-cell lymphoma. Am J Surg Pathol. 1997 Feb;21(2):187-94. PubMed
1996van de Rijn M, Kamel OW. Clonality of Epstein-Barr virus in lymphoproliferative disorders in patients treated with immunosuppressive therapy for rheumatoid arthritis. J Clin Oncol. 1996 Nov;14(11):3050-1. PubMed
Kamel OW, Weiss LM, van de Rijn M, Colby TV, Kingma DW, Jaffe ES. Hodgkin's disease and lymphoproliferations resembling Hodgkin's disease in patients receiving long-term low-dose methotrexate therapy. Am J Surg Pathol. 1996 Oct;20(10):1279-87. PubMed
Gelb AB, van de Rijn M, Warnke RA, Kamel OW. Pregnancy-associated lymphomas. A clinicopathologic study. Cancer. 1996 Jul 15;78(2):304-10. PubMed
Rothenberg ME, Ownbey R, Mehlhop PD, Loiselle PM, van de Rijn M, Bonventre JV, Oettgen HC, Leder P, Luster AD. Eotaxin triggers eosinophil-selective chemotaxis and calcium flux via a distinct receptor and induces pulmonary eosinophilia in the presence of interleukin 5 in mice. Mol Med. 1996 May;2(3):334-48. PubMed
van de Rijn M, Cleary ML, Variakojis D, Warnke RA, Chang PP, Kamel OW. Epstein-Barr virus clonality in lymphomas occurring in patients with rheumatoid arthritis. Arthritis Rheum. 1996 Apr;39(4):638-42. PubMed
von Luettichau I, Nelson PJ, Pattison JM, van de Rijn M, Huie P, Warnke R, Wiedermann CJ, Stahl RA, Sibley RK, Krensky AM. RANTES chemokine expression in diseased and normal human tissues. Cytokine. 1996 Jan;8(1):89-98. PubMed
1995van de Rijn M, Kamel OW. Cyclosporine and methotrexate for severe rheumatoid arthritis. N Engl J Med. 1995 Dec 7;333(23):1568; author reply 1568-9. PubMed
Kamel OW, Chang PP, Hsu FJ, Dolezal MV, Warnke RA, van de Rijn M. Clonal VDJ recombination of the immunoglobulin heavy chain gene by PCR in classical Hodgkin's disease. Am J Clin Pathol. 1995 Oct;104(4):419-23. PubMed
Arber DA, Kamel OW, van de Rijn M, Davis RE, Medeiros LJ, Jaffe ES, Weiss LM. Frequent presence of the Epstein-Barr virus in inflammatory pseudotumor. Hum Pathol. 1995 Oct;26(10):1093-8. PubMed
Hanasono MM, Kamel OW, Chang PP, Rizeq MN, Billingham ME, van de Rijn M. Detection of Epstein-Barr virus in cardiac biopsies of heart transplant patients with lymphoproliferative disorders. Transplantation. 1995 Sep 15;60(5):471-3. PubMed
Olsder NK, van Elburg RM, van de Rijn M, van Voorst Vader PC, de Monchy JG, Heymans HS. [Standardized multidisciplinary diagnosis of cow's milk protein allergy in children. Work Group Cow's Milk Protein Allergy of the Groningen Academic Hospital] Ned Tijdschr Geneeskd. 1995 Aug 19;139(33):1690-4. Dutch.
Morales-Ducret CR, van de Rijn M, Smoller BR. bcl-2 expression in melanocytic nevi. Insights into the biology of dermal maturation.Arch Dermatol. 1995 Aug;131(8):915-8. PubMed
Morales-Ducret CR, van de Rijn M, LeBrun DP, Smoller BR. bcl-2 expression inprimary malignancies of the skin. Arch Dermatol. 1995 Aug;131(8):909-12. PubMed
Dolezal MV, Kamel OW, van de Rijn M, Cleary ML, Sibley RK, Warnke RA. Virus-associated hemophagocytic syndrome characterized by clonal Epstein-Barr virus genome.Am J Clin Pathol. 1995 Feb;103(2):189-94. PubMed
Kamel OW, van de Rijn M, Hanasono MM, Warnke RA. Immunosuppression-associated lymphoproliferative disorders in rheumatic patients. Leuk Lymphoma. 1995 Feb;16(5-6):363-8. Review. Pubmed
1994Gelb AB, van de Rijn M, Regula DP Jr, Cornbleet JP, Kamel OW, Horoupian DS, Cleary ML, Warnke RA.Epstein-Barr virus-associated natural killer-large granular lymphocyte leukemia.Hum Pathol. 1994 Sep;25(9):953-60. PubMed
Bhargava V, Kell DL, van de Rijn M, Warnke RA. Bcl-2 immunoreactivity in breast carcinoma correlates with hormone receptor positivity.Am J Pathol. 1994 Sep;145(3):535-40. Pubmed
van de Rijn M, Hendrickson MR, Rouse RV. CD34 expression by gastrointestinal tract stromal tumors.Hum Pathol. 1994 Aug;25(8):766-71. PubMed
van de Rijn M, Lombard CM, Rouse RV. Expression of CD34 by solitary fibrous tumors of the pleura, mediastinum, and lung. Am J Surg Pathol. 1994 Aug;18(8):814-20. PubMed
Smoller BR, Van de Rijn M, Lebrun D, Warnke RA. bcl-2 expression reliably distinguishes trichoepitheliomas from basal cell carcinomas.Br J Dermatol. 1994 Jul;131(1):28-31. PubMed
Kamel OW, van de Rijn M, LeBrun DP, Weiss LM, Warnke RA, Dorfman RF. Lymphoid neoplasms in patients with rheumatoid arthritis and dermatomyositis: frequency of Epstein-Barr virus and other features associated with immunosuppression. Hum Pathol. 1994 Jul;25(7):638-43. PubMed
Rizeq MN, van de Rijn M, Hendrickson MR, Rouse RV. A comparative immunohistochemical study of uterine smooth muscle neoplasms with emphasis on the epithelioid variant. Hum Pathol. 1994 Jul;25(7):671-7. PubMed
1993van Spronsen FJ, van de Rijn M, van Dijk T, Smit GP, Reijngoud DJ, Berger R, Heymans HS. Plasma phenylalanine and tyrosine responses to different nutritional conditions (fasting/postprandial) in patients with phenylketonuria: effect of sample timing.Pediatrics. 1993 Oct;92(4):570-3.
Kamel OW, van de Rijn M, Weiss LM, Del Zoppo GJ, Hench PK, Robbins BA, Montgomery PG, Warnke RA, Dorfman RF. Brief report: reversible lymphomas associated with Epstein-Barr virus occurring during methotrexate therapy for rheumatoid arthritis and dermatomyositis. N Engl J Med. 1993 May 6;328(18):1317-21..
1992
Bax-van Meijel O, van de Rijn M, Uiterwaal D, van der Voort C, van Wijk-Wachtmeester M. [Obstetrical nursing and renewal of care] TVZ. 1992 Apr 2;(7):234-8. Dutch.
de Gruijter M, Hoogerbrugge N, van de Rijn M, Koster JF, Sluiter W, Jongkind JF. Patients with combined hypercholesterolemia-hypertriglyceridemia show an increased monocyte-endothelial cell adhesion in vitro: triglyceride level as a major determinant. Metabolism. 1991 Nov;40(11):1119-21.
1990van de Rijn M, Weissman IL, Siegelman M. Biosynthesis pathway of gp90MEL-14, the mouse lymph node-specific homing receptor. J Immunol. 1990 Sep 1;145(5):1477-82.
de Gruijter M, van de Rijn MA, Verkerk A, Jongkind JF. Isolation of human and porcine monocytes and lymphocytes by three parameter flow sorting. Zentralbl Veterinarmed A. 1990 Sep;37(8):585-91.
van de Rijn M, Regula DP Jr, Billingham M. Autopsy findings after coronary rotational atherectomy. Am J Cardiovasc Pathol. 1990;3(4):301-4.
1989van de Rijn M, Heimfeld S, Spangrude GJ, Weissman IL. Mouse hematopoietic stem-cell antigen Sca-1 is a member of the Ly-6 antigen family. Proc Natl Acad Sci U S A. 1989 Jun;86(12):4634-8.
Siegelman MH, van de Rijn M, Weissman IL. Mouse lymph node homing receptor cDNA clone encodes a glycoprotein revealing tandem interaction domains. Science. 1989 Mar 3;243(4895):1165-72.
1988Smit GP, Ververs MT, Belderok B, van de Rijn M, Berger R, Fernandes J. Complex carbohydrates in the dietary management of patients with glycogenosis caused by glucose-6-phosphatase deficiency. Am J Clin Nutr. 1988 Jul;48(1):95-7.
1986Spits H, van Schooten W, Keizer H, van Seventer G, van de Rijn M, Terhorst C, de Vries JE. Alloantigen recognition is preceded by nonspecific adhesion of cytotoxic T cells and target cells. Science. 1986 Apr 18;232(4748):403-5.
Lerch PG, van de Rijn M, Smart JE, Knowles RW, Terhorst C. Isolation and purification of the human thymocyte antigens T6 and M241. Mol Immunol. 1986 Feb;23(2):131-9.
1985Snow PM, van de Rijn M, Terhorst C. Association between the human thymic differentiation antigens T6 and T8.Eur J Immunol. 1985 May;15(5):529-32.
1984van de Rijn M, Bernabeu C, Royer-Pokora B, Weiss J, Seidman JG, de Vries J, Spits H, Terhorst C. Recognition of HLA-A2 by cytotoxic T lymphocytes after DNA transfer into human and murine cells. Science. 1984 Nov 30;226(4678):1083-5.
Bernabeu C, van de Rijn M, Lerch PG, Terhorst CP. Beta 2-microglobulin from serum associates with MHC class I antigens on the surface of cultured cells. Nature. 1984 Apr 12-18;308(5960):642-5.
van de Rijn M, Lerch PG, Bronstein BR, Knowles RW, Bhan AK, Terhorst C. Human cutaneous dendritic cells express two glycoproteins T6 and M241 which are biochemically identical to those found on cortical thymocytes. Hum Immunol. 1984 Apr;9(4):201-10.
1983Bernabeu C, Finlay D, van de Rijn M, Maziarz RT, Biro PA, Spits H, de Vries J, Terhorst CP. Expression of the major histocompatibility antigens HLA-A2 and HLA-B7 by DNA-mediated gene transfer. J Immunol. 1983 Oct;131(4):2032-7.
van de Rijn M, Lerch PG, Knowles RW, Terhorst C. The thymic differentiation markers T6 and M241 are two unusual MHC class I antigens.J Immunol. 1983 Aug;131(2):851-5.
Terhorst C, Borst J, Lerch P, van de Rijn M, Snow P, Spits H, de Vries J. Structural and functional aspects of the T-cell differentiation antigens T3, T6, and T8. Haematol Blood Transfus. 1983;28:440-6.
van de Rijn M, Geurts van Kessel AH, Kroezen V, van Agthoven AJ, Verstijnen K, Terhorst C, Hilgers J. Localization of a gene controlling the expression of the human transferrin receptor to the region q12 leads to qter of chromosome 3. Cytogenet Cell Genet. 1983;36(3):525-31.
Lerch PG, van de Rijn M, Schrier P, Terhorst C. Biochemical comparison of the T6 antigen and HLA-A,B antigens. Hum Immunol. 1983 Jan;6(1):13-30.
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