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Levy, Ronald, MD
(650) 725-6452 |
| Appointments |
| Chief,
Department of Oncology |
| Professor
of Oncology |
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| Honors & Awards |
| Jeffrey A. Gottlieb Memorial Award,
M.D. Anderson Cancer Center,
2003 |
| Evelyn
Hoffman Memorial Award, Lymphoma
Research Foundation of America , 2001 |
| Key to the Cure Award, Cure for Lymphoma Foundation,
2001 |
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view full list |
| Professional Education
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| A.B., Harvard University, 1963 |
| M.D., Stanford University, 1968 |
| Web Links |
| Lab site:
http://med.stanford.edu/labs/ronald_levy/ |
Research Intererests
Our research concentrates on the study of malignant lymphoma and tumors
of the immune system using the tools of immunology and molecular biology
to develop a better understanding of the initiation and progression of
the malignant process. Receptor molecules present on the surface of tumor
cells transmit signals for regulation of cell growth. These receptors
include the immunoglobulin molecule on B cell tumors and the T cell receptor
on T cell tumors. Questions the lab is currently addressing include:
- Can a clue to the pathogenesis of lymphoma be derived from a study
of their antigen receptors?
- Can new treatments for lymphoma be developed by targeting receptors
with monoclonal antibodies?
- Can vaccines be developed which can induce an immune response in
the host against the receptors on their own tumor?
Representative Publications
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Vuist W, Maloney D, Levy R. (1994). Lymphoma
regression induced by monoclonal anti-idiotypic antibodies correlates
with their ability to induce immunoglobulins signal transduction
and is not prevented by tumor expression of high levels of Bcl-2
protein. Blood 83(4):899–906. |
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Maloney D, Liles T, Czerwinski D, Waldichuk C, Rosenberg
J, Grillo-Lopez A, Levy R. (1994). Phase I clinical trial using
escalating single dose infusion of chimeric anti-CD20 monoclonal
antibody (IDEC-C2B8) in patients with recurrent B-cell lymphoma.
Blood 84(8):2457–2466. |
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Hsu F, Benike C, Fagnoni F, Liles TM, Czerwinski
D, Taidi B, Engleman EG, Levy R. (1996). Vaccination of patients
with B cell lymphoma using autologous antigen pulsed dendritic cells.
Nature Medicine 2:52–58. |
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Syrengelas A, Chen T, Levy R. (1996). DNA immunization
induces protective immunity against B cell lymphoma. Nature
Medicine 2: 1038–41. |
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Hsu F, Caspar C, Czerwinski D, Kwak L, Liles T,
Syrengelas A, Taidi-Laskowski B, Levy R. (1997). Tumor-specific
idiotype vaccines in the treatment of patients with B cell lymphoma;
long-term results of a clinical trial. Blood 89:3129-3135.
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Complete list
of publications
Medline Search
Medline search for Levy, Ronald
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