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The Cardiothoracic Transplantation Laboratory at Stanford Medical School was founded in the early 1960's by transplantation pioneer Dr. Norman E. Shumway to develop and refine the orthotopic cardiac transplant model. Innovative thinking, skillful application of surgical technique, as well as dedication and perseverance towards achieving difficult goals, have been a trademark of this laboratory since its inception. From the first long-term surviving cardiac transplant performed by Dr. Shumway's Stanford team in 1968 to the development of new immunosuppressive agents in the 1970's, the first successful heart-lung transplant in 1981, and the ongoing development of cutting-edge technology including gene therapy and stem-cell models, the Stanford Cardiothoracic Transplantation Laboratory has remained one of the world's pre-eminent labs in the increasingly complex and dynamic field of cardiothoracic organ transplantation and transplant immunology. The transplant laboratory has offered first-rate surgical and academic training to hundreds of young residents, medical students, and scientists over the past four decades, including many internationally recognized leaders in the field. After Dr. Shumway and Dr. Richard Lower, assisted by veterinarian Raymond Stofer, developed the working canine cardiac transplant model that led to the first clinical transplant at Stanford in 1968, Dr. Edward Stinson joined the research team and subsequently became a technically gifted and medically brilliant transplant surgeon who helped guide the fledgling transplant program at Stanford through its early years. In the early 1970's, Drs. Philip Oyer, Philip Caves, and Randall Griepp rotated through the lab before completing surgical training and becoming prominent transplant surgeons in their own right. Dr. Caves' invention of the cardiac bioptome in the laboratory brought a vitally important technique, still regarded as the "gold standard" for evaluating rejection, into the clinical world. |
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