Ongoing Research:
in the laboratory of richard bland, M.D.
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IN
SITU HYBRIDIZATION FOR TROPOELASTIN mRNA IN PULMONARY ARTERIES
OF LAMBS. Increased tropoelastin in preterm lamb with chronic lung
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ACUTE AND CHRONIC LUNG DISEASE AFTER PREMATURE BIRTH - Mechanisms that Regulate Lung Structure and Function During Development, Injury and Repair
Goals:
• Better understanding of what regulates
respiratory tract and pulmonary vascular development
• Better understanding of the pathogenesis of lung injury and subsequent
repair
• Development of safe and effective therapeutic interventions in animals
before they are applied in human infants
Our group's research focuses on the pathogenesis and treatment of acute and chronic neonatal lung injury and on the mechanisms that regulate lung fluid balance, alveolar and pulmonary vascular development after premature birth. The science is integrative biology, with coordinated and complementary studies of:
• The physiology of the pulmonary
circulation and respiratory tract
• The histopathology of the lung during neonatal development, injury and
repair
• The biochemical, cellular, and molecular events that are important in
regulating these processes
