Journal Club 2019-2020

Both MCTI and CSI students are required to attend the IMMUNOL 305 Immunology Journal Club for their First through Third years. Attendance is optional for Fourth year and above graduate students.

Announcement for Journal Club 2019-2020: Journal Club will now be open to faculty. Please refer to the schedule below. Faculty are encouraged to attend. The paper of the week will continue to be presented by a student, but we ask that the presenting student’s advisor make every effort to attend the journal club to facilitate discussion.  If your student is presenting, they will contact you about scheduling. Papers will be posted on this page each week.

Fall Quarter: Tuesdays at 3:00-4:00 pm, LKSC Room 308
Winter Quarter: Tuesdays at 10:30-11:30am, LKSC Room 308
Spring Quarter: Tuesdays at TBD, LKSC Room 308

Check back weekly for the paper that will be presented at Journal Club.

Sep September 24 Tue 2019

Brenda Velasco, Shizuru Lab
Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis.

Wu C, et al. Inflammasome Activation Triggers Blood Clotting and Host Death through Pyroptosis. Immunity. 2019 Jun 18;50(6):1401-1411.e4. doi: 10.1016/j.immuni.2019.04.003. Epub 2019 May 7. PMID: 31076358.

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Oct October 01 Tue 2019

Frank Buquicchio, Satpathy Lab
TOX Transcriptionally and Epigenetically Programs CD8 T Cell Exhaustion.

Khan O, et al. TOX Transcriptionally and Epigenetically Programs CD8 T Cell Exhaustion. Nature. 2019 Jul;571(7764):211-218. doi: 10.1038/s41586-019-1325-x. Epub 2019 Jun 17. PMID: 31207603.

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Oct October 08 Tue 2019

Bryan Cannon, Bendall Lab
The Alzheimer’s Disease–Associated Protein BACE1 Modulates T Cell Activation and Th17 Function

Hernandez-Mir, Gerard, et al. The Alzheimer’s Disease–Associated Protein BACE1 Modulates T Cell Activation and Th17 Function. J Immunol. 2019 Aug 1;203(3):665-675. doi: 10.4049/jimmunol.1800363. Epub 2019 Jun 17. PMCID: PMC6650361.

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Oct October 15 Tue 2019

YeEun Kim, Bendall and Greenleaf Labs
NF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration 

Yamashita M, Passegué E.  TNF-α Coordinates Hematopoietic Stem Cell Survival and Myeloid Regeneration. Cell Stem Cell. 2019 Sep 5;25(3):357-372.e7. doi: 10.1016/j.stem.2019.05.019. Epub 2019 Jun 20. PMCID: PMC6733032.

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Oct October 22 Tue 2019

Audrey Lee, Pulendran Lab
Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells

Liu Z, et al. Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells. Cell. 2019 Sep 5;178(6):1509-1525.e19. doi: 10.1016/j.cell.2019.08.009. PMID: 31491389.

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Oct October 29 Tue 2019

Josselyn Pena, Krams Lab
Endogenous glucocorticoids control host resistance to viral infection through the tissue-specific regulation of PD-1 expression on NK cells

Quatrini L, et al. Endogenous glucocorticoids control host resistance to viral infection through the tissue-specific regulation of PD-1 expression on NK cells. Nat Immunol. 2018 Sep;19(9):954-962. doi: 10.1038/s41590-018-0185-0. Epub 2018 Aug 20. PMID: 30127438; PMCID: PMC6138242.

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Nov November 05 Tue 2019

Medeea Popescu, Bollyky and Quake Labs
Denisovan, Modern Human and Mouse TNFAIP3 Alleles Tune A20 Phosphorylation and Immunity

Zammit NW, et. al. Denisovan, Modern Human and Mouse TNFAIP3 Alleles Tune A20 Phosphorylation and Immunity. Nat Immunol. 2019 Oct;20(10):1299-1310. doi: 10.1038/s41590-019-0492-0. Epub 2019 Sep 18. PMID: 31534238.

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Nov November 12 Tue 2019

Alex Muselman, Engleman Lab
Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity

Jarjour NN, Schwarzkopf EA, Bradstreet TR, Shchukina I, Lin CC, Huang SC, Lai CW, Cook ME, Taneja R, Stappenbeck TS, Randolph GJ, Artyomov MN, Urban JF Jr, Edelson BT. Bhlhe40 mediates tissue-specific control of macrophage proliferation in homeostasis and type 2 immunity. Nat Immunol. 2019 Jun;20(6):687-700. doi: 10.1038/s41590-019-0382-5. Epub 2019 May 6. PMID: 31061528; PMCID: PMC6531324.

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Nov November 19 Tue 2019

Kameron Rodrigues, Jaiswal and Montgomery Labs
Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles

Petrova VN, Sawatsky B, Han AX, Laksono BM, Walz L, Parker E, Pieper K, Anderson CA, de Vries RD, Lanzavecchia A, Kellam P, von Messling V, de Swart RL, Russell CA. Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles. Sci Immunol. 2019 Nov 1;4(41). pii: eaay6125. doi: 10.1126/sciimmunol.aay6125. PMID: 31672862.

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Dec December 03 Tue 2019

Hunter Martinez, Bollyky Lab
Class-Switch Recombination Occurs Infrequently in Germinal Centers

Roco JA, Mesin L, Binder SC, Nefzger C, Gonzalez-Figueroa P, Canete PF, Ellyard J, Shen Q, Robert PA, Cappello J, Vohra H, Zhang Y, Nowosad CR, Schiepers A, Corcoran LM, Toellner KM, Polo JM, Meyer-Hermann M, Victora GD, Vinuesa CG. Class-Switch Recombination Occurs Infrequently in Germinal Centers. Immunity. 2019 Aug 20;51(2):337-350.e7. doi: 10.1016/j.immuni.2019.07.001. Epub 2019 Jul 30. PMID: 31375460.

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