Researchers engineered stem cell-derived heart tissues to study how tachycardia affects the heart and to uncover the inner workings of our body’s engine.

Circulating tumor DNA predicts recurrence and splits disease into two subgroups in Stanford Medicine-led study of Hodgkin lymphoma. New drug targets or changes in treatments may reduce toxicity.

Testing drugs “in a dish” using heart and blood vessel cells can speed drug development and reduce health care disparities, cardiologist says.

Children’s noses pack a punch that could help explain COVID-19’s typically mild course in young kids. Researchers hope to parlay that ‘nasal magic’ into increased protections for adults.

Data from wearables show that deviations from normal sleep and activity in pregnancy are connected to a risk for premature delivery, a Stanford Medicine-led study found.

Determining the order of authors on a scientific paper can be tricky. Unless you're a pair of video gaming graduate students. Recently Stanford researcher Garry Nolan, PhD, tweeted about an unconventional way two researchers in his laboratory who had each contributed equally to a study decided who should be listed first on the print version of the paper.

As the government moves to Plan B - what actually happens when you catch the new variant?

A Q&A with one of the foremost scientists studying UAPs, and what he hopes to learn by systematically studying bizarre and difficult-to-explain incidents. Dr. Garry Nolan is a Professor of Pathology at Stanford University. His research ranges from cancer to systems immunology. Dr. Garry Nolan has also spent the last ten years working with a number of individual analyzing materials from alleged Unidentified Aerial Phenomenon.

The preliminary findings could partially explain why people living with obesity are at higher risk of severe covid-19. “This could well be contributing to severe disease,” senior author, Catherine Blish, an immunologist at the Stanford University School of Medicine, told the New York Times. “We’re seeing the same inflammatory cytokines that I see in the blood of the really sick patients being produced in response to infection of those tissues.”

Injections of blood from young adult mice that are getting lots of exercise benefited the brains of sedentary mice the same age, according to a study by the Stanford School of Medicine in California. 'The discovery could open the door to treatments that, by taming brain inflammation in people who don't get much exercise, lower their risk of neurodegenerative disease or slow its progression,' said Professor Tony Wyss-Coray, of the Stanford School of Medicine in California, which carried out the research.

CAR-T cell therapy works for many types of blood cancers, but more than half of patients relapse. A Stanford study provides a clue as to why. The researchers showed a correlation between the density of the target molecules on the cell surface and the likelihood that a patient will respond well to CAR-T cell therapy. They also devised a way to assess the function of engineered CAR-T cells before they are used in patients. Crystal Mackall, MD, the Ernest and Amelia Gallo Family Professor and a professor of pediatrics and of medicine and David Miklos, MD, PhD, professor of medicine and chief of bone marrow transplantation and cellular therapy are co-senior authors of the study, which was published online July 26 in Nature Medicine.

Certain additives can strengthen vaccines to protect the body from a broad range of viruses, researchers at the Stanford School of Medicine found in a study published in late June in Cell. Lead author Florian Wimmers found that a chemical can boost immune defenses to various viruses when added to vaccines.

A study looks beyond T and B cell responses to show how the Pfizer COVID-19 vaccine elicits a strong innate immune response. The Scientist spoke with lead author Bali Pulendran, an immunologist at Stanford University, about what he and his colleagues found regarding the Pfizer vaccine’s effects on the immune system.

A new way to deliver mRNA as a COVID-19 vaccine may avoid side effects and increase customization to prevent infection. Now immunologist and oncologist Ronald Levy, MD, and chemists Paul Wender, PhD, and Robert Waymouth, PhD, are exploring another way to get viral mRNA into cells using a novel technique I wrote about in 2018. They published their results recently in ACS Central Science.

In COVID-19 patients whose symptoms were mild, Stanford researchers found that they were more likely than sicker patients to have signs of prior infection by similar, less virulent coronaviruses. Senior author, Mark Davis, PhD, a professor of microbiology and immunology; director of Stanford’s Institute for Immunity, Transplantation and Infection; and a Howard Hughes Medical Institute investigator and first author, postdoctoral fellow Vamsee Mallajosyula, PhD, first confirmed that some portions of SARS-CoV-2’s sequence are effectively identical to analogous portions of one or more of the four widespread common-cold-causing coronavirus strains.

Scientists and companies are trying to harness the mRNA technology to develop vaccines against cancer and other diseases. Bali Pulendran, Violetta L. Horton Professor And Professor Of Microbiology And Immunology and of Pathology, comments on the future on vaccines.

A detailed molecular analysis of tissue from the brains of individuals who died of COVID-19 reveals extensive signs of inflammation and neurodegeneration, but no sign of the virus that causes the disease. Tony Wyss-Coray, PhD, professor of neurology and neurological sciences at Stanford, shares senior authorship with Andreas Keller, PhD, chair of clinical bioinformatics at Saarland University.

Air levels of pollen and mold spores in the San Francisco Bay Area are elevated for about two more months per year than in past decades, and higher temperatures are to blame, a Stanford Medicine study has found, led by senior author, Kari Nadeau, MD, PhD, professor of medicine and of pediatrics at Stanford School of Medicine.

The 2021 Faculty Women’s Forum Awards honor individuals for their outstanding work supporting women at Stanford through role modeling, allyship, leadership and sponsorship. Stanford Immunology faculty Dr. Joy Wu, an associate professor of medicine (endocrinology, gerontology and metabolism) in the School of Medicine is honored in the Allyship Award category.

Stanford researchers found that data from smartwatches can flag early signs of some health conditions and predict the results of simple blood tests. Scientists from the lab of Michael Snyder, PhD, professor and chair of genetics, tracked data from smartwatches, blood tests and other tests conducted in a doctor’s office in a small group of study participants.

Protein levels in people’s blood can predict their age, a Stanford study has found. The study also found that aging isn’t a smoothly continuous process.

CAR-T cells are remarkably effective against blood cancers, but their effect can be transient as the cells become exhausted. Stanford researchers found a way to keep the cells effective in mice with human tumors.

Hongjie Dai, Julie Parsonnet and Joseph Wu are among the 90 regular members and 10 international members elected this year to the academy, which aims to provide independent, scientifically informed analysis and recommendations on health issues.

“Never could I have imagined the work I am doing now – not even ten years ago.” - Devavani Chatterjea, PhD, MPH

Researchers at Stanford and UCSF slowed the spread of a type of nonsmall cell lung cancer in mice by neutralizing a single protein that would otherwise set off a chain reaction, causing runaway tumor growth.

David Schneider, whose research focuses on resilience to infection and developing mathematical models to predict recovery and well-being, succeeds Peter Sarnow in post.

In the trial, a new drug proved safe and effective for hard-to-treat rheumatoid arthritis patients. A national organization of senior researchers named the trial one of the top 10 for 2016.

A common signaling pathway unites diverse fibrotic diseases in humans, Stanford researchers have found. An antibody called anti-CD47, which is being tested as an anti-cancer agent, reverses fibrosis in mice.

To develop a potential antiviral treatment, Stanford researchers adopted an unusual approach: Rather than trying to disable viral enzymes, they targeted proteins the infected individual makes — and the virus needs.

The researchers will be given funding by the Chan Zuckerberg Biohub to develop tools and technologies that support the organization’s goal of curing, preventing or managing every disease.